Page last updated: 2024-10-27

gbr 12935 and Parkinson Disease, Secondary

gbr 12935 has been researched along with Parkinson Disease, Secondary in 2 studies

1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine : An N-alkylpiperazine that consists of piperazine bearing 2-(benzhydryloxy)ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal membranes).

Parkinson Disease, Secondary: Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected condition. Examples include parkinsonism caused by vascular injury, drugs, trauma, toxin exposure, neoplasms, infections and degenerative or hereditary conditions. Clinical features may include bradykinesia, rigidity, parkinsonian gait, and masked facies. In general, tremor is less prominent in secondary parkinsonism than in the primary form. (From Joynt, Clinical Neurology, 1998, Ch38, pp39-42)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Massie, A1
Goursaud, S1
Schallier, A1
Vermoesen, K1
Meshul, CK1
Hermans, E1
Michotte, Y1
Ossowska, K1
Wardas, J1
Smiałowska, M1
Kuter, K1
Lenda, T1
Wierońska, JM1
Zieba, B1
Nowak, P1
Dabrowska, J1
Bortel, A1
Kwieciński, A1
Wolfarth, S1

Other Studies

2 other studies available for gbr 12935 and Parkinson Disease, Secondary

ArticleYear
Time-dependent changes in GLT-1 functioning in striatum of hemi-Parkinson rats.
    Neurochemistry international, 2010, Volume: 57, Issue:5

    Topics: Animals; Aspartic Acid; Blotting, Western; Chromatography, High Pressure Liquid; Corpus Striatum; Do

2010
A slowly developing dysfunction of dopaminergic nigrostriatal neurons induced by long-term paraquat administration in rats: an animal model of preclinical stages of Parkinson's disease?
    The European journal of neuroscience, 2005, Volume: 22, Issue:6

    Topics: Algorithms; Animals; Autoradiography; Caudate Nucleus; Dopamine; Herbicides; Male; Neurons; Neurotra

2005