gbr 12935 has been researched along with Nerve Degeneration in 2 studies
1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine : An N-alkylpiperazine that consists of piperazine bearing 2-(benzhydryloxy)ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal membranes).
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Norlén, M | 1 |
| Allard, P | 1 |
| Chritin, M | 1 |
| Blanchard, V | 1 |
| Raisman-Vozari, R | 1 |
| Feuerstein, C | 1 |
| Agid, Y | 1 |
| Javoy-Agid, F | 1 |
| Savasta, M | 1 |
2 other studies available for gbr 12935 and Nerve Degeneration
| Article | Year |
|---|---|
Reduction in number of dopamine uptake sites but unchanged number of piperazine-acceptor/CYP450IID6 binding sites in the human caudate nucleus in aging.
Topics: Adult; Aged; Aged, 80 and over; Aging; Binding Sites; Caudate Nucleus; Cytochrome P-450 CYP2D6; Fema | 1996 |
DA uptake sites, D1 and D2 receptors, D2 and preproenkephalin mRNAs and Fos immunoreactivity in rat striatal subregions after partial dopaminergic degeneration.
Topics: Animals; Binding Sites; Corpus Striatum; Denervation; Dopamine; Enkephalins; Immunohistochemistry; M | 1996 |