gbr 12935 has been researched along with Disease Models, Animal in 6 studies
1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine : An N-alkylpiperazine that consists of piperazine bearing 2-(benzhydryloxy)ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal membranes).
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Drugs were subsequently tested for potential long-lasting effects on brain tissue 5-HT after repeated dosing (2." | 1.31 | Serotonin transporters, serotonin release, and the mechanism of fenfluramine neurotoxicity. ( Ayestas, MA; Baumann, MH; Dersch, CM; Partilla, JS; Rothman, RB, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Simchon, Y | 1 |
| Weizman, A | 1 |
| Rehavi, M | 1 |
| Hébert, G | 1 |
| Arsaut, J | 1 |
| Dantzer, R | 1 |
| Demotes-Mainard, J | 1 |
| Battaglia, G | 1 |
| Farrace, MG | 1 |
| Mastroberardino, PG | 1 |
| Viti, I | 1 |
| Fimia, GM | 1 |
| Van Beeumen, J | 1 |
| Devreese, B | 1 |
| Melino, G | 1 |
| Molinaro, G | 1 |
| Busceti, CL | 1 |
| Biagioni, F | 1 |
| Nicoletti, F | 1 |
| Piacentini, M | 1 |
| Baumann, MH | 1 |
| Ayestas, MA | 1 |
| Dersch, CM | 1 |
| Partilla, JS | 1 |
| Rothman, RB | 1 |
6 other studies available for gbr 12935 and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
The effect of chronic methylphenidate administration on presynaptic dopaminergic parameters in a rat model for ADHD.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Binding Sites; Brain; Central Nervous System | 2010 |
Time-course of the expression of inflammatory cytokines and matrix metalloproteinases in the striatum and mesencephalon of mice injected with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, a dopaminergic neurotoxin.
Topics: Animals; Cytokines; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; E | 2003 |
Transglutaminase 2 ablation leads to defective function of mitochondrial respiratory complex I affecting neuronal vulnerability in experimental models of extrapyramidal disorders.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine Triphosphate; Animals; Basal Ganglia Disease | 2007 |
Serotonin transporters, serotonin release, and the mechanism of fenfluramine neurotoxicity.
Topics: Analysis of Variance; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Disease | 2000 |