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gbr 12935 and Astrocytosis

gbr 12935 has been researched along with Astrocytosis in 1 studies

1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine : An N-alkylpiperazine that consists of piperazine bearing 2-(benzhydryloxy)ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal membranes).

Research Excerpts

ExcerptRelevanceReference
"Thus, carnosine prevents the microgliosis in striatum (where we did not detect loss of serotonergic terminals by [3H]paroxetine binding) and the expression of HSP27 in all the areas, but fails to prevent methamphetamine-induced loss of dopamine reuptake sites."1.31Carnosine prevents methamphetamine-induced gliosis but not dopamine terminal loss in rats. ( Camarasa, J; Camins, A; Escubedo, E; Pallàs, M; Pubill, D; Sureda, FX; Verdaguer, E, 2002)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pubill, D1
Verdaguer, E1
Sureda, FX1
Camins, A1
Pallàs, M1
Camarasa, J1
Escubedo, E1

Other Studies

1 other study available for gbr 12935 and Astrocytosis

ArticleYear
Carnosine prevents methamphetamine-induced gliosis but not dopamine terminal loss in rats.
    European journal of pharmacology, 2002, Jul-19, Volume: 448, Issue:2-3

    Topics: Animals; Carnosine; Corpus Striatum; Gliosis; Hippocampus; Male; Methamphetamine; Piperazines; Presy

2002