gbr 12935 has been researched along with Aging in 5 studies
1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine : An N-alkylpiperazine that consists of piperazine bearing 2-(benzhydryloxy)ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal membranes).
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gordon, I | 1 |
| Weizman, R | 1 |
| Rosenne, E | 1 |
| Rehavi, M | 1 |
| Norlén, M | 1 |
| Allard, P | 1 |
| Moll, GH | 1 |
| Mehnert, C | 1 |
| Wicker, M | 1 |
| Bock, N | 1 |
| Rothenberger, A | 1 |
| Rüther, E | 1 |
| Huether, G | 1 |
| Le, WD | 1 |
| Bostwick, JR | 1 |
| Appel, SH | 1 |
| Zelnik, N | 1 |
| Angel, I | 1 |
| Paul, SM | 1 |
| Kleinman, JE | 1 |
5 other studies available for gbr 12935 and Aging
| Article | Year |
|---|---|
Developmental and age-related alterations in rat brain presynaptic dopaminergic mechanisms.
Topics: Age Factors; Aging; Amphetamine; Animals; Binding, Competitive; Brain; Carrier Proteins; Corpus Stri | 1995 |
Reduction in number of dopamine uptake sites but unchanged number of piperazine-acceptor/CYP450IID6 binding sites in the human caudate nucleus in aging.
Topics: Adult; Aged; Aged, 80 and over; Aging; Binding Sites; Caudate Nucleus; Cytochrome P-450 CYP2D6; Fema | 1996 |
Age-associated changes in the densities of presynaptic monoamine transporters in different regions of the rat brain from early juvenile life to late adulthood.
Topics: Aging; Animals; Brain; Brain Stem; Carrier Proteins; Corpus Striatum; Dopamine Plasma Membrane Trans | 2000 |
Use of [3H]-GBR12935 to measure dopaminergic nerve terminal growth into the developing rat striatum.
Topics: Aging; Animals; Biological Transport; Corpus Striatum; Dopamine; Embryonic and Fetal Development; Ge | 1992 |
Decreased density of human striatal dopamine uptake sites with age.
Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Corpus Striatum; Dopamine; Female; Humans; | 1986 |