gatifloxacin has been researched along with Torsade de Pointes in 4 studies
Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.
gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ciprofloxacin was associated with a significantly lower rate of torsades de pointes (0." | 1.31 | Rates of torsades de pointes associated with ciprofloxacin, ofloxacin, levofloxacin, gatifloxacin, and moxifloxacin. ( Frothingham, R, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chiba, K | 1 |
| Sugiyama, A | 1 |
| Hagiwara, T | 1 |
| Takahashi, S | 1 |
| Takasuna, K | 1 |
| Hashimoto, K | 1 |
| Fteha, A | 1 |
| Fteha, E | 1 |
| Haq, S | 1 |
| Kozer, L | 1 |
| Saul, B | 1 |
| Kassotis, J | 1 |
| Frothingham, R | 1 |
| Bertino, JS | 1 |
| Owens, RC | 1 |
| Carnes, TD | 1 |
| Iannini, PB | 1 |
4 other studies available for gatifloxacin and Torsade de Pointes
| Article | Year |
|---|---|
In vivo experimental approach for the risk assessment of fluoroquinolone antibacterial agents-induced long QT syndrome.
Topics: Administration, Oral; Animals; Aza Compounds; Blood Pressure; Chloralose; Disease Models, Animal; Do | 2004 |
Gatifloxacin induced torsades de pointes.
Topics: Aged; Aged, 80 and over; Female; Fluoroquinolones; Gatifloxacin; Humans; Torsades de Pointes | 2004 |
Rates of torsades de pointes associated with ciprofloxacin, ofloxacin, levofloxacin, gatifloxacin, and moxifloxacin.
Topics: Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Electrocardiography; Fluoroquinolones; Gatiflox | 2001 |
Gatifloxacin-associated corrected QT interval prolongation, torsades de pointes, and ventricular fibrillation in patients with known risk factors.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Female; Fluoroquinolones; Gatifloxacin; Heart; Human | 2002 |