Page last updated: 2024-11-04

gatifloxacin and Pterygium

gatifloxacin has been researched along with Pterygium in 2 studies

Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.
gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.

Pterygium: An abnormal triangular fold of membrane in the interpalpebral fissure, extending from the conjunctiva to the cornea, being immovably united to the cornea at its apex, firmly attached to the sclera throughout its middle portion, and merged with the conjunctiva at its base. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"To compare the rate of corneal epithelial healing and ocular tolerability following pterygium surgery between gatifloxacin and moxifloxacin."9.22The effect of gatifloxacin 0.3% or moxifloxacin 0.5% on corneal healing, ocular tolerability and toxicity following pterygium surgery. ( Geffen, N; Mimouni, M; Rosen, E; Segev, F, 2016)
"To document the development of corneal perforation after using gatifloxacin to treat inflamed pterygium."3.74Corneal perforation associated with topically applied gatifloxacin. ( Al-Amri, AM, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mimouni, M1
Geffen, N1
Rosen, E1
Segev, F1
Al-Amri, AM1

Trials

1 trial available for gatifloxacin and Pterygium

ArticleYear
The effect of gatifloxacin 0.3% or moxifloxacin 0.5% on corneal healing, ocular tolerability and toxicity following pterygium surgery.
    Cutaneous and ocular toxicology, 2016, Volume: 35, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Benzalkonium Compounds; Double-Blind Method;

2016

Other Studies

1 other study available for gatifloxacin and Pterygium

ArticleYear
Corneal perforation associated with topically applied gatifloxacin.
    Cornea, 2008, Volume: 27, Issue:3

    Topics: Administration, Topical; Adult; Anti-Infective Agents; Cornea; Corneal Diseases; Fluoroquinolones; G

2008