Page last updated: 2024-11-04

gatifloxacin and Pink Eye

gatifloxacin has been researched along with Pink Eye in 4 studies

Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.
gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.

Research Excerpts

ExcerptRelevanceReference
"In the rabbit keratitis model, the ocular inflammation was significantly reduced by gatifloxacin as compared to levofloxacin but there was no significant difference between the groups in the number of viable bacteria."7.74Immunomodulatory effect of gatifloxacin on mouse peritoneal macrophages in vitro and in models of endotoxin-induced rat conjunctivitis and rabbit bacterial keratitis. ( Inoue, T; Kida, T; Naka, H; Sakaki, H; Tokushige, H; Wada, T, 2008)
"To determine the safety and efficacy of black tea extract in the treatment of bacterial conjunctivitis in a rabbit model and compare it with that of gatifloxacin drops."4.31Safety and Efficacy of Black Tea Extract in the Treatment of Acute Bacterial Conjunctivitis: A Rabbit Model. ( Abdullatif, AM; Hassan, LM; Marrie, A; Shash, RY, 2023)
"In the rabbit keratitis model, the ocular inflammation was significantly reduced by gatifloxacin as compared to levofloxacin but there was no significant difference between the groups in the number of viable bacteria."3.74Immunomodulatory effect of gatifloxacin on mouse peritoneal macrophages in vitro and in models of endotoxin-induced rat conjunctivitis and rabbit bacterial keratitis. ( Inoue, T; Kida, T; Naka, H; Sakaki, H; Tokushige, H; Wada, T, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Abdullatif, AM1
Hassan, LM1
Shash, RY1
Marrie, A1
Betanzos-Cabrera, G1
Juárez-Verdayes, MA1
González-González, G1
Cancino-Díaz, ME1
Cancino-Díaz, JC1
Gorle, AP1
Gattani, SG1
Wada, T1
Kida, T1
Inoue, T1
Tokushige, H1
Naka, H1
Sakaki, H1

Other Studies

4 other studies available for gatifloxacin and Pink Eye

ArticleYear
Safety and Efficacy of Black Tea Extract in the Treatment of Acute Bacterial Conjunctivitis: A Rabbit Model.
    Eye & contact lens, 2023, Jan-01, Volume: 49, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Conjunctivitis; Conjunctivitis, Bacterial; Fluoroquinolones; Gatiflo

2023
Gatifloxacin, moxifloxacin, and balofloxacin resistance due to mutations in the gyrA and parC genes of Staphylococcus epidermidis strains isolated from patients with endophthalmitis, corneal ulcers and conjunctivitis.
    Ophthalmic research, 2009, Volume: 42, Issue:1

    Topics: Anti-Infective Agents; Aza Compounds; Conjunctivitis; Corneal Ulcer; DNA Gyrase; DNA Topoisomerase I

2009
Design and evaluation of polymeric ocular drug delivery system.
    Chemical & pharmaceutical bulletin, 2009, Volume: 57, Issue:9

    Topics: Animals; Anti-Infective Agents; Conjunctivitis; Drug Compounding; Drug Delivery Systems; Drug Design

2009
Immunomodulatory effect of gatifloxacin on mouse peritoneal macrophages in vitro and in models of endotoxin-induced rat conjunctivitis and rabbit bacterial keratitis.
    Ophthalmic research, 2008, Volume: 40, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Aza Compounds; Cells, Cultured; Conjunctivitis; Endotoxins; Fluor

2008