gatifloxacin has been researched along with Pancreatic Neoplasms in 2 studies
Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.
gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gatifloxacin can cause both hypoglycemia and hyperglycemia in both diabetic and non-diabetic patients." | 1.33 | Gatifloxacin acutely stimulates insulin secretion and chronically suppresses insulin biosynthesis. ( Inagaki, N; Kawasaki, Y; Nagashima, K; Seino, Y; Takahashi, A; Ueno, H; Yamada, C; Yamada, Y, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yadav, V | 1 |
| Sultana, S | 1 |
| Yadav, J | 1 |
| Saini, N | 1 |
| Yamada, C | 1 |
| Nagashima, K | 1 |
| Takahashi, A | 1 |
| Ueno, H | 1 |
| Kawasaki, Y | 1 |
| Yamada, Y | 1 |
| Seino, Y | 1 |
| Inagaki, N | 1 |
2 other studies available for gatifloxacin and Pancreatic Neoplasms
| Article | Year |
|---|---|
Gatifloxacin induces S and G2-phase cell cycle arrest in pancreatic cancer cells via p21/p27/p53.
Topics: Anti-Infective Agents; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Prolifer | 2012 |
Gatifloxacin acutely stimulates insulin secretion and chronically suppresses insulin biosynthesis.
Topics: Animals; Anti-Infective Agents; Blood Glucose; Cell Line, Tumor; Cell Separation; Fluoroquinolones; | 2006 |