gatifloxacin has been researched along with Neoplasms in 5 studies
Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.
gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gatifloxacin (GA) is an alternative, though it has not been thoroughly studied in Pediatrics yet." | 6.73 | Oral gatifloxacin in the outpatient treatment of children with cancer fever and neutropenia. ( Alberto Pires Pereira, C; Altruda Carlesse, F; Petrilli, A, 2007) |
| "Gatifloxacin (GA) is an alternative, though it has not been thoroughly studied in Pediatrics yet." | 2.73 | Oral gatifloxacin in the outpatient treatment of children with cancer fever and neutropenia. ( Alberto Pires Pereira, C; Altruda Carlesse, F; Petrilli, A, 2007) |
| "Gatifloxacin was very active against Acinetobacter lwoffi (MIC100 0." | 1.32 | In vitro antimicrobial activity of gatifloxacin compared with other quinolones against clinical isolates from cancer patients. ( Frisbee-Hume, S; LeBlanc, B; Rolston, KV; Streeter, H; Vaziri, I, 2004) |
| "Gatifloxacin was more potent than either ciprofloxacin or levofloxacin against all Gram-positive species." | 1.30 | Antimicrobial activity of gatifloxacin compared to seven other compounds tested against gram-positive organisms isolated at 10 cancer-treatment centers. ( Diekema, DJ; Jones, RN; Rolston, KV, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Azéma, J | 1 |
| Guidetti, B | 1 |
| Dewelle, J | 1 |
| Le Calve, B | 1 |
| Mijatovic, T | 1 |
| Korolyov, A | 1 |
| Vaysse, J | 1 |
| Malet-Martino, M | 1 |
| Martino, R | 1 |
| Kiss, R | 1 |
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Rolston, KV | 2 |
| Vaziri, I | 1 |
| Frisbee-Hume, S | 1 |
| Streeter, H | 1 |
| LeBlanc, B | 1 |
| Petrilli, A | 1 |
| Altruda Carlesse, F | 1 |
| Alberto Pires Pereira, C | 1 |
| Diekema, DJ | 1 |
| Jones, RN | 1 |
1 review available for gatifloxacin and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
1 trial available for gatifloxacin and Neoplasms
| Article | Year |
|---|---|
Oral gatifloxacin in the outpatient treatment of children with cancer fever and neutropenia.
Topics: Administration, Oral; Adolescent; Adult; Ambulatory Care; Anti-Infective Agents; Antineoplastic Agen | 2007 |
3 other studies available for gatifloxacin and Neoplasms
| Article | Year |
|---|---|
7-((4-Substituted)piperazin-1-yl) derivatives of ciprofloxacin: synthesis and in vitro biological evaluation as potential antitumor agents.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Ciprofloxacin; Humans; Maximum | 2009 |
In vitro antimicrobial activity of gatifloxacin compared with other quinolones against clinical isolates from cancer patients.
Topics: Anti-Bacterial Agents; Enterococcus; Fermentation; Fluoroquinolones; Follow-Up Studies; Gatifloxacin | 2004 |
Antimicrobial activity of gatifloxacin compared to seven other compounds tested against gram-positive organisms isolated at 10 cancer-treatment centers.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Cancer Care Facilities; Drug Resistance, Microbial; Fl | 1999 |