gatifloxacin has been researched along with Infection, Mycobacterium avium-intracellulare in 2 studies
Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.
gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Four patients did not complete the 1-year treatment because of adverse events." | 2.77 | The clinical efficacy and safety of a fluoroquinolone-containing regimen for pulmonary MAC disease. ( Fujita, M; Harada, E; Ikegame, S; Kajiki, A; Matsumoto, T; Miyazaki, M; Nakanishi, Y; Ouchi, H; Tao, Y; Uchino, J; Watanabe, K, 2012) |
| " When the three FQs were individually combined with CLR in vitro, mild antagonism was observed for 53 to 57% of the tested isolates." | 1.34 | In vitro and in vivo activities of novel fluoroquinolones alone and in combination with clarithromycin against clinically isolated Mycobacterium avium complex strains in Japan. ( Fukushima, K; Higashiyama, Y; Hirakata, Y; Kohno, S; Kohno, Y; Miyazaki, Y; Ohno, H; Yanagihara, K, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kohno, Y | 1 |
| Ohno, H | 1 |
| Miyazaki, Y | 1 |
| Higashiyama, Y | 1 |
| Yanagihara, K | 1 |
| Hirakata, Y | 1 |
| Fukushima, K | 1 |
| Kohno, S | 1 |
| Fujita, M | 1 |
| Kajiki, A | 1 |
| Tao, Y | 1 |
| Miyazaki, M | 1 |
| Ouchi, H | 1 |
| Harada, E | 1 |
| Ikegame, S | 1 |
| Matsumoto, T | 1 |
| Uchino, J | 1 |
| Watanabe, K | 1 |
| Nakanishi, Y | 1 |
1 trial available for gatifloxacin and Infection, Mycobacterium avium-intracellulare
| Article | Year |
|---|---|
The clinical efficacy and safety of a fluoroquinolone-containing regimen for pulmonary MAC disease.
Topics: Aged; Antitubercular Agents; Clarithromycin; Drug Therapy, Combination; Ethambutol; Female; Fluoroqu | 2012 |
1 other study available for gatifloxacin and Infection, Mycobacterium avium-intracellulare
| Article | Year |
|---|---|
In vitro and in vivo activities of novel fluoroquinolones alone and in combination with clarithromycin against clinically isolated Mycobacterium avium complex strains in Japan.
Topics: Animals; Aza Compounds; Clarithromycin; Drug Therapy, Combination; Fluoroquinolones; Gatifloxacin; H | 2007 |