gatifloxacin has been researched along with Meningitis, Bacterial in 3 studies
Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.
gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.
Meningitis, Bacterial: Bacterial infections of the leptomeninges and subarachnoid space, frequently involving the cerebral cortex, cranial nerves, cerebral blood vessels, spinal cord, and nerve roots.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gatifloxacin therapy was more rapidly bactericidal than cefotaxime but similar to meropenem therapy (bacterial killing rates at 5 h, 0." | 1.30 | Efficacy of gatifloxacin in experimental Escherichia coli meningitis. ( Friedland, IR; Ghaffar, F; Jafri, HS; Lutsar, I; McCracken, GH; Ng, W; Wubbel, L, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McCarthy, KL | 1 |
| Looke, DF | 1 |
| Lutsar, I | 1 |
| Friedland, IR | 1 |
| Jafri, HS | 1 |
| Wubbel, L | 1 |
| Ng, W | 1 |
| Ghaffar, F | 1 |
| McCracken, GH | 1 |
| Perrig, M | 1 |
| Acosta, F | 1 |
| Cottagnoud, M | 1 |
| Gerber, CM | 1 |
| Täuber, MG | 1 |
| Cottagnoud, P | 1 |
3 other studies available for gatifloxacin and Meningitis, Bacterial
| Article | Year |
|---|---|
Successful treatment of post-neurosurgical intracranial Mycoplasma hominis infection using gatifloxacin.
Topics: Adolescent; Anti-Bacterial Agents; Brain Abscess; Female; Fluoroquinolones; Gatifloxacin; Humans; Ma | 2008 |
Efficacy of gatifloxacin in experimental Escherichia coli meningitis.
Topics: Animals; Anti-Infective Agents; Escherichia coli; Escherichia coli Infections; Fluoroquinolones; Gat | 1999 |
Efficacy of gatifloxacin alone and in combination with cefepime against penicillin-resistant Streptococcus pneumoniae in a rabbit meningitis model and in vitro.
Topics: Animals; Anti-Infective Agents; Cefepime; Cephalosporins; Disease Models, Animal; Drug Therapy, Comb | 2001 |