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gatifloxacin and Infections, Pseudomonas

gatifloxacin has been researched along with Infections, Pseudomonas in 11 studies

Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.
gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.

Research Excerpts

ExcerptRelevanceReference
"3% is at least as effective as ciprofloxacin at healing corneal ulcers infected with Pseudomonas aeruginosa when gatifloxacin is administered less frequently than ciprofloxacin."7.73Comparison of ophthalmic gatifloxacin 0.3% and ciprofloxacin 0.3% in healing of corneal ulcers associated with Pseudomonas aeruginosa-induced ulcerative keratitis in rabbits. ( Carrier, M; Jensen, H; Short, B; Zerouala, C, 2005)
"3% is at least as effective as ciprofloxacin at healing corneal ulcers infected with Pseudomonas aeruginosa when gatifloxacin is administered less frequently than ciprofloxacin."3.73Comparison of ophthalmic gatifloxacin 0.3% and ciprofloxacin 0.3% in healing of corneal ulcers associated with Pseudomonas aeruginosa-induced ulcerative keratitis in rabbits. ( Carrier, M; Jensen, H; Short, B; Zerouala, C, 2005)
"Besifloxacin-treated eyes had significantly lower CFU recovered as compared with that of gatifloxacin- and moxifloxacin-treated eyes (P < 0."1.37Comparison of besifloxacin, gatifloxacin, and moxifloxacin against strains of pseudomonas aeruginosa with different quinolone susceptibility patterns in a rabbit model of keratitis. ( Hesje, CK; Marquart, ME; Moore, QC; Norcross, EW; Sanders, ME; Sanfilippo, CM; Shafiee, A, 2011)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's8 (72.73)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sivagurunathan, N1
Krishnan, S1
Rao, JV1
Nagappa, AN1
Subrahmanyam, VM1
Vanathi, BM1
Sanders, ME1
Moore, QC1
Norcross, EW1
Sanfilippo, CM1
Hesje, CK1
Shafiee, A1
Marquart, ME1
Karlowsky, JA1
Jones, ME1
Thornsberry, C1
Evangelista, AT1
Yee, YC1
Sahm, DF1
Jensen, H1
Zerouala, C1
Carrier, M1
Short, B1
Moshirfar, M1
Mirzaian, G1
Feiz, V1
Kang, PC1
Epstein, SP1
Bottone, EJ1
Asbell, PA1
Sirvent, E1
Ruiz, M1
Rodríguez, JC1
Royo, G1
Mah, FS1
Romanowski, EG1
Kowalski, RP1
Yates, KA1
Gordon, YJ1
Sato, A2
Kitazawa, H2
Chida, K2
Hayakawa, H2
Iwata, M2
Jones, RN1
Beach, ML1
Pfaller, MA1

Other Studies

11 other studies available for gatifloxacin and Infections, Pseudomonas

ArticleYear
Synergy of gatifloxacin with cefoperazone and cefoperazone-sulbactam against resistant strains of Pseudomonas aeruginosa.
    Journal of medical microbiology, 2008, Volume: 57, Issue:Pt 12

    Topics: Anti-Bacterial Agents; Cefoperazone; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combi

2008
Comparison of besifloxacin, gatifloxacin, and moxifloxacin against strains of pseudomonas aeruginosa with different quinolone susceptibility patterns in a rabbit model of keratitis.
    Cornea, 2011, Volume: 30, Issue:1

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Aza Compounds; Azepines; Colony Count, Micr

2011
Stable antimicrobial susceptibility rates for clinical isolates of Pseudomonas aeruginosa from the 2001-2003 tracking resistance in the United States today surveillance studies.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Feb-15, Volume: 40 Suppl 2

    Topics: beta-Lactams; Ceftazidime; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Ga

2005
Comparison of ophthalmic gatifloxacin 0.3% and ciprofloxacin 0.3% in healing of corneal ulcers associated with Pseudomonas aeruginosa-induced ulcerative keratitis in rabbits.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2005, Volume: 21, Issue:1

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Cornea; Corneal Ulcer; Disea

2005
Fourth-generation fluoroquinolone-resistant bacterial keratitis after refractive surgery.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:3

    Topics: Adult; Aza Compounds; Bacteria; Cornea; Corneal Ulcer; Drug Resistance, Bacterial; Drug Therapy, Com

2006
Susceptibility testing of clinical isolates of pseudomonas aeruginosa to levofloxacin, moxifloxacin, and gatifloxacin as a guide to treating pseudomonas ocular infections.
    Eye & contact lens, 2006, Volume: 32, Issue:5

    Topics: Anti-Bacterial Agents; Aza Compounds; Drug Resistance, Multiple, Bacterial; Eye Infections, Bacteria

2006
[Study investigating the activity of several fluoroquinolones against Pseudomonas aeruginosa using the mutant prevention concentration].
    Enfermedades infecciosas y microbiologia clinica, 2006, Volume: 24, Issue:10

    Topics: Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Cross Infection; Dose-Response Relationship, Dr

2006
Zymar (Gatifloxacin 0.3%) shows excellent Gram-negative activity against Serratia marcescens and Pseudomonas aeruginosa in a New Zealand White rabbit keratitis model.
    Cornea, 2007, Volume: 26, Issue:5

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Corneal Ulcer; Disease Model

2007
Study of the effects of AM-1155 in a rat chronic respiratory tract infection model with Pseudomonas aeruginosa.
    Drugs, 1995, Volume: 49 Suppl 2

    Topics: Animals; Anti-Infective Agents; Chronic Disease; Fluoroquinolones; Gatifloxacin; Immunoglobulin A; L

1995
Effect of 6-fluoro-8-methoxy quinolone (AM-1155) against chronic airway infection with Pseudomonas aeruginosa in a rat model.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:2

    Topics: Animals; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Disease Models, Animal; Fluoroquinol

1997
Spectrum and activity of three contemporary fluoroquinolones tested against Pseudomonas aeruginosa isolates from urinary tract infections in the SENTRY Antimicrobial Surveillance Program (Europe and the Americas; 2000): more alike than different!
    Diagnostic microbiology and infectious disease, 2001, Volume: 41, Issue:3

    Topics: Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary; Cipro

2001