gatifloxacin has been researched along with Group A Strep Infection in 5 studies
Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.
gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pharmacodynamic parameters of peak serum drug concentration/MIC (peak/MIC) ratio and the area under the curve (AUC)/MIC ratio have been used to characterize in vivo drug exposure and its relationship to bacterial killing for the fluoroquinolones." | 1.31 | Pharmacodynamic assessment of gatifloxacin against Streptococcus pneumoniae. ( Banevicius, M; Li, D; Mattoes, HM; Nicolau, DP; Nightingale, CH; Turley, C; Xuan, D, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Proksch, JW | 1 |
| Ward, KW | 1 |
| Tamazawa, G | 1 |
| Ito, A | 1 |
| Miyai, T | 1 |
| Matsuno, T | 1 |
| Kitahara, K | 1 |
| Sogo, Y | 1 |
| Kimishima, K | 1 |
| Satoh, T | 1 |
| Rondina, MT | 1 |
| Raphael, K | 1 |
| Pendleton, R | 1 |
| Sande, MA | 1 |
| Jones, RN | 1 |
| Johnson, DM | 1 |
| Erwin, ME | 1 |
| Beach, ML | 1 |
| Biedenbach, DJ | 1 |
| Pfaller, MA | 1 |
| Mattoes, HM | 1 |
| Banevicius, M | 1 |
| Li, D | 1 |
| Turley, C | 1 |
| Xuan, D | 1 |
| Nightingale, CH | 1 |
| Nicolau, DP | 1 |
5 other studies available for gatifloxacin and Group A Strep Infection
| Article | Year |
|---|---|
Ocular pharmacokinetics/pharmacodynamics of besifloxacin, moxifloxacin, and gatifloxacin following topical administration to pigmented rabbits.
Topics: Administration, Topical; Animals; Aqueous Humor; Area Under Curve; Aza Compounds; Azepines; Conjunct | 2010 |
Gatifloxacine-loaded PLGA and β-tricalcium phosphate composite for treating osteomyelitis.
Topics: Absorbable Implants; Animals; Anti-Infective Agents; Bacteriological Techniques; Bacteroides fragili | 2011 |
Abdominal aortitis due to Streptococcus pneumoniae and Enterobacter aerogenes: a case report and review.
Topics: Aged; Aorta, Abdominal; Aortitis; Coronary Angiography; Enterobacter aerogenes; Enterobacteriaceae I | 2006 |
Comparative antimicrobial activity of gatifloxacin tested against Streptococcus spp. including quality control guidelines and etest method validation. Quality Control Study Group.
Topics: Anti-Infective Agents; Fluoroquinolones; Gatifloxacin; Humans; Microbial Sensitivity Tests; Penicill | 1999 |
Pharmacodynamic assessment of gatifloxacin against Streptococcus pneumoniae.
Topics: Animals; Anti-Infective Agents; Area Under Curve; Colony Count, Microbial; Disease Models, Animal; F | 2001 |