gatifloxacin has been researched along with Electrocardiogram QT Prolonged in 7 studies
Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.
gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report the case of a 54-year-old woman who, while being treated for acute sinusitis with gatifloxacin, presented with syncope and was found to have a markedly prolonged QT interval." | 3.72 | Gatifloxacin and prolonged QT interval. ( Ansari, SR; Chopra, N, 2004) |
| " In contrast, hyperglycemia without QT/QTc prolongations was noted 24 h after dosing in one animal." | 1.48 | Usefulness of simultaneous and sequential monitoring of glucose level and electrocardiogram in monkeys treated with gatifloxacin under conscious and nonrestricted conditions. ( Chiba, K; Ishizaka, T; Mori, K; Yoshimatsu, Y, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cavalli, A | 1 |
| Poluzzi, E | 1 |
| De Ponti, F | 1 |
| Recanatini, M | 1 |
| Yoshimatsu, Y | 1 |
| Ishizaka, T | 1 |
| Chiba, K | 2 |
| Mori, K | 1 |
| Ansari, SR | 1 |
| Chopra, N | 1 |
| Sugiyama, A | 1 |
| Hagiwara, T | 1 |
| Takahashi, S | 1 |
| Takasuna, K | 1 |
| Hashimoto, K | 1 |
| Anderson, ME | 1 |
| Mazur, A | 1 |
| Yang, T | 1 |
| Roden, DM | 1 |
| Lannini, PB | 1 |
| Circiumaru, I | 1 |
| Bertino, JS | 1 |
| Owens, RC | 1 |
| Carnes, TD | 1 |
| Iannini, PB | 1 |
7 other studies available for gatifloxacin and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go- | 2002 |
Usefulness of simultaneous and sequential monitoring of glucose level and electrocardiogram in monkeys treated with gatifloxacin under conscious and nonrestricted conditions.
Topics: Administration, Oral; Animals; Blood Glucose; Consciousness; Dose-Response Relationship, Drug; Elect | 2018 |
Gatifloxacin and prolonged QT interval.
Topics: Acute Disease; Electrocardiography; Female; Fluoroquinolones; Gatifloxacin; Humans; Long QT Syndrome | 2004 |
In vivo experimental approach for the risk assessment of fluoroquinolone antibacterial agents-induced long QT syndrome.
Topics: Administration, Oral; Animals; Aza Compounds; Blood Pressure; Chloralose; Disease Models, Animal; Do | 2004 |
Potassium current antagonist properties and proarrhythmic consequences of quinolone antibiotics.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Arrhythmias, Cardiac; Aza Compounds; Cation Transport | 2001 |
Gatifloxacin-induced QTc prolongation and ventricular tachycardia.
Topics: Aged; Anti-Infective Agents; Female; Fluoroquinolones; Gatifloxacin; Humans; Long QT Syndrome; Synco | 2001 |
Gatifloxacin-associated corrected QT interval prolongation, torsades de pointes, and ventricular fibrillation in patients with known risk factors.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Female; Fluoroquinolones; Gatifloxacin; Heart; Human | 2002 |