gatifloxacin has been researched along with Dermatitis, Contact, Phototoxic in 3 studies
Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.
gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In vivo phototoxicity studies are important to predict drug-induced phototoxicity in humans; however, a standard methodology has not established." | 1.46 | The abdominal skin of female Sprague-Dawley rats is more sensitive than the back skin to drug-induced phototoxicity. ( Harada, Y; Kuga, K; Miyamoto, M; Miyamoto, Y; Sakai, Y; Sato, K; Shimizu, F; Takamatsu, Y; Yasuno, H, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sanchez, JP | 1 |
| Gogliotti, RD | 1 |
| Domagala, JM | 1 |
| Gracheck, SJ | 1 |
| Huband, MD | 1 |
| Sesnie, JA | 1 |
| Cohen, MA | 1 |
| Shapiro, MA | 1 |
| Kuga, K | 1 |
| Yasuno, H | 1 |
| Sakai, Y | 1 |
| Harada, Y | 1 |
| Shimizu, F | 1 |
| Miyamoto, Y | 1 |
| Takamatsu, Y | 1 |
| Miyamoto, M | 1 |
| Sato, K | 1 |
| Chawla, S | 1 |
| Chogtu, B | 1 |
| Gupta, U | 1 |
| Grover, C | 1 |
3 other studies available for gatifloxacin and Dermatitis, Contact, Phototoxic
| Article | Year |
|---|---|
The synthesis, structure-activity, and structure-side effect relationships of a series of 8-alkoxy- and 5-amino-8-alkoxyquinolone antibacterial agents.
Topics: Animals; Anti-Bacterial Agents; Bacteria; CHO Cells; Cricetinae; Dermatitis, Phototoxic; Drug Design | 1995 |
The abdominal skin of female Sprague-Dawley rats is more sensitive than the back skin to drug-induced phototoxicity.
Topics: Abdomen; Administration, Oral; Animals; Back; Dermatitis, Phototoxic; Disease Models, Animal; Doxycy | 2017 |
Phototoxic drug reaction to gatifloxacin.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Dermatitis, Phototoxic; Fluoroquinolones; Gatifl | 2006 |