gatifloxacin has been researched along with Corneal Diseases in 7 studies
Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.
gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.
Corneal Diseases: Diseases of the cornea.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To document the development of corneal perforation after using gatifloxacin to treat inflamed pterygium." | 3.74 | Corneal perforation associated with topically applied gatifloxacin. ( Al-Amri, AM, 2008) |
| "Gatifloxacin was discontinued and substituted with a neomycin-polymixin B-dexamethasone ophthalmic ointment." | 1.32 | Corneal intrastromal gatifloxacin crystal deposits after penetrating keratoplasty. ( Awwad, ST; Cavanagh, HD; Conger, D; Haddad, W; Parmar, D; Wang, MX, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elia, M | 1 |
| Khodadadeh, S | 1 |
| Chow, J | 1 |
| Moshirfar, M | 1 |
| Chew, J | 1 |
| Werner, L | 1 |
| Meyer, JJ | 1 |
| Hunter, B | 1 |
| Stevens, S | 1 |
| Jensen, M | 1 |
| Kleinmann, G | 1 |
| Mamalis, N | 1 |
| Awwad, ST | 2 |
| Haddad, W | 1 |
| Wang, MX | 2 |
| Parmar, D | 1 |
| Conger, D | 1 |
| Cavanagh, HD | 2 |
| Wittpenn, JR | 1 |
| Barequet, IS | 1 |
| Habot-Wilner, Z | 1 |
| Lavinsky, F | 1 |
| Ziv, H | 1 |
| Belkin, M | 1 |
| Rosner, M | 1 |
| Al-Amri, AM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Clinical Trial Comparing the Effect of Moxifloxacin Versus Gatifloxacin Following Pterygium Excision on Corneal Epithelial Healing and Epithelial Toxicity.[NCT00892918] | 40 participants (Anticipated) | Interventional | 2009-06-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for gatifloxacin and Corneal Diseases
| Article | Year |
|---|---|
Corneal crystalline deposits associated with topically applied gatifloxacin.
Topics: Administration, Topical; Anti-Bacterial Agents; Cataract Extraction; Corneal Diseases; Corneal Strom | 2014 |
Comparison of the effects of fourth-generation fluoroquinolones on corneal re-epithelialization in rabbit eyes.
Topics: Administration, Topical; Animals; Anti-Infective Agents; Aza Compounds; Benzalkonium Compounds; Corn | 2008 |
Corneal intrastromal gatifloxacin crystal deposits after penetrating keratoplasty.
Topics: Aged; Aged, 80 and over; Corneal Diseases; Corneal Stroma; Crystallization; Drug Therapy, Combinatio | 2004 |
Crystallization of gatifloxacin after penetrating keratoplasty.
Topics: Corneal Diseases; Corneal Stroma; Crystallization; Fluoroquinolones; Gatifloxacin; Granuloma, Foreig | 2005 |
A case of gatifloxacin crystal deposits in the corneal graft of an 85-year-old man.
Topics: Aged, 80 and over; Corneal Diseases; Corneal Stroma; Crystallization; Fluoroquinolones; Gatifloxacin | 2006 |
Effect of fourth-generation fluoroquinolones on the healing rate of corneal erosions in an animal model.
Topics: Animals; Anti-Infective Agents; Aza Compounds; Corneal Diseases; Disease Models, Animal; Epithelium, | 2007 |
Corneal perforation associated with topically applied gatifloxacin.
Topics: Administration, Topical; Adult; Anti-Infective Agents; Cornea; Corneal Diseases; Fluoroquinolones; G | 2008 |