Page last updated: 2024-11-04

gatifloxacin and Body Weight

gatifloxacin has been researched along with Body Weight in 3 studies

Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.
gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"The effects of age on gatifloxacin pharmacokinetic values were largely attributed to declining renal function, whereas those of gender were largely attributed to differences in body weight."3.70Age and gender effects on the pharmacokinetics of gatifloxacin. ( Behr, D; Duncan, G; Grasela, DM; Kollia, GD; LaCreta, FP, 2000)
" Pharmacokinetic parameters were estimated by fitting appropriate models to the serum concentration-time data using ADAPT II."2.72Gatifloxacin pharmacokinetics in healthy men and women. ( Kays, MB; Overholser, BR; Sowinski, KM; Zhang, X, 2006)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Piubello, A1
Harouna, SH1
Souleymane, MB1
Boukary, I1
Morou, S1
Daouda, M1
Hanki, Y1
Van Deun, A1
Zhang, X1
Overholser, BR1
Kays, MB1
Sowinski, KM1
LaCreta, FP1
Kollia, GD1
Duncan, G1
Behr, D1
Grasela, DM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Culture Free Diagnosis and Follow-up of Multidrug Resistant Tuberculosis Patients[NCT03303963]3,356 participants (Actual)Observational2017-05-04Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for gatifloxacin and Body Weight

ArticleYear
Gatifloxacin pharmacokinetics in healthy men and women.
    Journal of clinical pharmacology, 2006, Volume: 46, Issue:10

    Topics: Administration, Oral; Adult; Anti-Infective Agents; Area Under Curve; Body Weight; Chromatography, H

2006

Other Studies

2 other studies available for gatifloxacin and Body Weight

ArticleYear
High cure rate with standardised short-course multidrug-resistant tuberculosis treatment in Niger: no relapses.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2014, Volume: 18, Issue:10

    Topics: Adolescent; Adult; Aged; Body Mass Index; Body Weight; Clofazimine; Dose-Response Relationship, Drug

2014
Age and gender effects on the pharmacokinetics of gatifloxacin.
    Pharmacotherapy, 2000, Volume: 20, Issue:6 Pt 2

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Infective Agents; Body Weight; Female; Fluoroquino

2000