Page last updated: 2024-11-04

gatifloxacin and Astigmatism

gatifloxacin has been researched along with Astigmatism in 2 studies

Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.
gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.

Astigmatism: Unequal curvature of the refractive surfaces of the eye. Thus a point source of light cannot be brought to a point focus on the retina but is spread over a more or less diffuse area. This results from the radius of curvature in one plane being longer or shorter than the radius at right angles to it. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Eyes treated with moxifloxacin healed faster and had smaller defects compared with those treated with gatifloxacin."2.71The effect of fourth-generation fluoroquinolones gatifloxacin and moxifloxacin on epithelial healing following photorefractive keratectomy. ( Bower, KS; Burka, JM; Howard, RS; Kuzmowych, CP; Stutzman, RD; Vanroekel, RC, 2005)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burka, JM1
Bower, KS1
Vanroekel, RC1
Stutzman, RD1
Kuzmowych, CP1
Howard, RS1
Ursea, R1
Purcell, TL1
Tan, BU1
Nalgirkar, A1
Lovaton, ME1
Ehrenhaus, MR1
Schanzlin, DJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Clinical Trial Comparing the Effect of Moxifloxacin Versus Gatifloxacin Following Pterygium Excision on Corneal Epithelial Healing and Epithelial Toxicity.[NCT00892918]40 participants (Anticipated)Interventional2009-06-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for gatifloxacin and Astigmatism

ArticleYear
The effect of fourth-generation fluoroquinolones gatifloxacin and moxifloxacin on epithelial healing following photorefractive keratectomy.
    American journal of ophthalmology, 2005, Volume: 140, Issue:1

    Topics: Adult; Anti-Infective Agents; Antibiotic Prophylaxis; Astigmatism; Aza Compounds; Double-Blind Metho

2005

Other Studies

1 other study available for gatifloxacin and Astigmatism

ArticleYear
The effect of cyclosporine A (Restasis) on recovery of visual acuity following LASIK.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2008, Volume: 24, Issue:5

    Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Astigmatism; Cyclosporine; Drug Therapy

2008