gatifloxacin has been researched along with Aging in 2 studies
Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.
gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "First, a previously derived population pharmacokinetic model, with patient demographics, was used to estimate gatifloxacin AUC0-24 following a dosage regimen of 400 mg/24 h in 10 index patients with severe hyperglycaemia." | 1.32 | Gatifloxacin and the elderly: pharmacokinetic-pharmacodynamic rationale for a potential age-related dose reduction. ( Ambrose, PG; Bhavnani, SM; Cirincione, BB; Grasela, TH; Piedmonte, M, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ambrose, PG | 1 |
| Bhavnani, SM | 1 |
| Cirincione, BB | 1 |
| Piedmonte, M | 1 |
| Grasela, TH | 1 |
| Fedler, KA | 1 |
| Jones, RN | 1 |
| Sader, HS | 1 |
| Fritsche, TR | 1 |
2 other studies available for gatifloxacin and Aging
| Article | Year |
|---|---|
Gatifloxacin and the elderly: pharmacokinetic-pharmacodynamic rationale for a potential age-related dose reduction.
Topics: Aged; Aged, 80 and over; Aging; Algorithms; Anti-Bacterial Agents; Area Under Curve; Bayes Theorem; | 2003 |
Activity of gatifloxacin tested against isolates from pediatric patients: report from the SENTRY Antimicrobial Surveillance Program (North America, 1998-2003).
Topics: Adolescent; Adult; Aged; Aging; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Child; Child, | 2006 |