gatifloxacin has been researched along with Absence Seizure in 4 studies
Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.
gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This case of gatifloxacin-induced seizures may reflect a class-effect phenomenon versus an effect caused by an individual fluoroquinolone." | 3.72 | Possible gatifloxacin-induced seizure. ( Lederman, JR; Quigley, CA, 2004) |
| "The clinical risk of convulsion for each combination was estimated using a pharmacodynamic model based on receptor occupancy using the in vitro data set obtained and pharmacokinetic parameters in humans collected from the literature." | 1.35 | Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents. ( Kim, J; Ohtani, H; Sawada, Y; Tsujimoto, M, 2009) |
| " The results showed proconvulsant effect of gatifloxacin (50 mg/kg) in pentylenetetrazole-induced seizure test after both short- and long-term administration studies." | 1.35 | Anxiogenic and proconvulsant effect of gatifloxacin in mice. ( Bharal, N; Gupta, S; Khurana, S; Mediratta, PK; Sharma, KK, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, J | 1 |
| Ohtani, H | 1 |
| Tsujimoto, M | 1 |
| Sawada, Y | 1 |
| Quigley, CA | 1 |
| Lederman, JR | 1 |
| Frothingham, R | 1 |
| Bharal, N | 1 |
| Gupta, S | 1 |
| Khurana, S | 1 |
| Mediratta, PK | 1 |
| Sharma, KK | 1 |
4 other studies available for gatifloxacin and Absence Seizure
| Article | Year |
|---|---|
Quantitative comparison of the convulsive activity of combinations of twelve fluoroquinolones with five nonsteroidal antiinflammatory agents.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Cipr | 2009 |
Possible gatifloxacin-induced seizure.
Topics: Aged; Aged, 80 and over; Fluoroquinolones; Gatifloxacin; Humans; Intensive Care Units; Male; Seizure | 2004 |
Chlamydia pneumoniae and acute coronary syndrome.
Topics: Anti-Bacterial Agents; Cardiovascular Diseases; Cause of Death; Chlamydophila Infections; Chlamydoph | 2005 |
Anxiogenic and proconvulsant effect of gatifloxacin in mice.
Topics: Administration, Oral; Affect; Animals; Anti-Infective Agents; Anxiety; Behavior, Animal; Dose-Respon | 2008 |