gastrodin has been researched along with Disease Models, Animal in 44 studies
*Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (2.27) | 29.6817 |
| 2010's | 21 (47.73) | 24.3611 |
| 2020's | 22 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, WP; Chern, Y; Fang, JM; Huang, NK; Lin, CI; Lin, YL | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Ma, S; Sun, Y; Yang, Y; Zheng, X | 1 |
| Ao, L; Chen, M; Chen, S; Chen, WS; Feng, X; Liao, C; Liao, Y; Liu, Y; Luo, K; Wang, Y | 1 |
| Chou, AH; Hu, LM; Lee, HC; Liao, CC; Liu, FC; Yu, HP | 1 |
| Eyvari-Brooshghalan, S; Haddadi, R; Nourouzi, N; Sabahi, M; Sadeghian, Z | 1 |
| Cao, G; Chen, C; Cui, J; Feng, L; Jia, Z; Liu, Y; Shan, W; Shi, L; Song, Y; Sun, Y; Tan, Y; Yi, W; Zhang, B; Zhang, M; Zhu, M | 1 |
| Chen, L; Chen, Y; Fu, J; He, Y; Liu, J; Yu, Q; Yuan, S; Zhang, Y | 1 |
| Cheng, H; Guo, S; Ke, G; Liu, M; Mao, Y; Mi, Y; Wang, M; Wei, P | 1 |
| Hu, XF; Jin, XP; Ke, SF; Liu, XC; Wang, E; Wang, TL; Wu, CZ; Wu, G | 1 |
| Bai, C; Chen, C; Dai, Z; Du, T; Ji, B; Li, X; Rao, Q; Shi, R; Tian, M; Wang, H; Weng, Z; Xiao, C; Yang, W; Yu, X; Zhang, C; Zheng, CB | 1 |
| Liu, CM; Ma, JQ; Ming, QL; Sun, YZ; Tian, ZK; Zhang, YJ | 1 |
| Ji, LP; Liu, CM; Ma, JQ; Ming, QL; Tian, ZK; Zhang, YJ | 1 |
| Huang, H; Jin, L; Lin, J; Qu, S; Yang, S; Yuan, B; Zeng, Z; Zhang, H | 1 |
| Bao, ZR; Guo, J; Li, F; Li, JJ; Li, LS; Wu, CY; Yang, XK; Yuan, Y; Zhang, XL; Zi, Y | 1 |
| Bao, H; Chen, L; Wang, W; Wang, X; Wang, Y; Xu, Y; Zhang, Z; Zheng, J | 1 |
| Chiu, SC; Huang, CW; Lai, MC; Liu, PY; Wu, SN; Yang, CS | 1 |
| Li, AY; Wang, Y; Zhao, L | 1 |
| Han, J; Li, Y; Wang, Y; Yang, Y | 1 |
| Chen, H; Guan, Z; Shao, F; Zhang, Y; Zhou, L | 1 |
| Han, SS; Hou, J; Li, CX; Liu, FY; Pang, WL; Sun, CB; Wang, C; Wen, J; Xing, HJ; Yan, JY; Yang, ZS; Yin, W; Ying, Y; Yuan, JL; Zhang, SQ; Zhou, LC | 1 |
| He, J; Li, X; Li, Y; Lin, X; Liu, Y; Xiu, M; Yang, S | 1 |
| Ding, Y; Fang, Q; Hu, S; Liang, Y; Liu, Z; Tian, S; Wan, J; Yang, D; Yang, L; Zhang, Y | 1 |
| Jiang, X; Liao, C; Song, D; Sun, Y; Zhang, Z; Zhou, J | 1 |
| Akerman, S; Goadsby, PJ; Martins-Oliveira, M; Zhao, Y | 1 |
| Jiang, JD; Kong, WJ; Wang, C; Yu, B; Zhang, Y | 1 |
| Liang, P; Zhang, JM; Zhao, XM; Zhou, NN; Zhu, R | 1 |
| He, JY; Li, F; Liu, SY; Liu, ZY; Qiu, CW; Xiao, ZC; Zhang, FL; Zhang, L | 1 |
| Huang, Y; Long, H; Ruan, J; Wang, C; Zhang, M | 1 |
| Ahmad, O; Cheng, L; Deng, Y; Li, M; Ma, K; Shang, J; Wang, B; Yang, L; Yang, Y; Zhao, J; Zhou, Q | 1 |
| Fu, Q; Liu, X; Wang, Y; Wu, Z | 1 |
| Chen, Y; Nie, H; Peng, Z; Tan, Q; Wang, H; Wang, Y; Wu, D; Xue, F; Zhang, R | 1 |
| Nie, H; Peng, Z; Qiao, Y; Tan, Q; Wang, H; Wang, Y; Xue, F; Zhang, R; Zhang, Z | 1 |
| Hu, Y; Li, C; Shen, W | 1 |
| Li, A; Zhang, F | 1 |
| Li, Y; Zhang, Z | 1 |
| Li, HB; Miao, HC; Wu, F; Xiong, KR; Zhu, XL | 1 |
| Deng, JB; Guo, JN; He, WY; Liang, HM; Wang, Q; Zhang, JS; Zhou, SF | 1 |
| Hahm, DH; Lee, B; Lee, H; Shim, I; Sur, B; Yeom, M | 1 |
| Cao, XY; Hong, P; Ji, WG; Qi, AP; Shao, H; Yang, Y; Zhu, GX; Zhu, ZR | 1 |
| Deng, Y; Gong, Q; Li, F; Liu, B; Shi, J; Yang, D | 1 |
| Liang, P; Zhao, XM; Zhou, NN; Zhu, R | 1 |
| Chen, L; Liu, X; Qu, M; Wang, H | 1 |
| Cai, Z; Hou, S; Liu, Z; Song, X; Sun, F; Yang, Z | 1 |
44 other study(ies) available for gastrodin and Disease Models, Animal
| Article | Year |
|---|---|
Neuroprotective principles from Gastrodia elata.
Topics: Adenosine; Animals; Apoptosis; Disease Models, Animal; Drugs, Chinese Herbal; Gastrodia; Molecular Structure; Neuroprotective Agents; PC12 Cells; Plants, Medicinal; Rats; Receptor, Adenosine A2A; Serum; Sulfides | 2007 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Gastrodin attenuates perfluorooctanoic acid-induced liver injury by regulating gut microbiota composition in mice.
Topics: Animals; Benzyl Alcohols; Caprylates; Cecum; Cytokines; Disease Models, Animal; Fatty Acids, Volatile; Fluorocarbons; Gastrointestinal Microbiome; Glucosides; Hepatomegaly; Inflammation Mediators; Liver; Male; Mice, Inbred C57BL; Oxidative Stress; Phylogeny; Protective Agents | 2021 |
Treatment Combining Focused Ultrasound with Gastrodin Alleviates Memory Deficit and Neuropathology in an Alzheimer's Disease-Like Experimental Mouse Model.
Topics: Alzheimer Disease; Animals; Benzyl Alcohols; Blood-Brain Barrier; Brain; Combined Modality Therapy; Disease Models, Animal; Glucosides; Maze Learning; Memory Disorders; Mice; Neuroprotective Agents; Ultrasonography, Interventional | 2022 |
Gastrodin Alleviates Acetaminophen-Induced Liver Injury in a Mouse Model Through Inhibiting MAPK and Enhancing Nrf2 Pathways.
Topics: Acetaminophen; Animals; Antioxidants; Benzyl Alcohols; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Disease Models, Animal; Glucosides; Liver; Mice; NF-E2-Related Factor 2; Oxidative Stress | 2022 |
Post treatment with Gastrodin suppresses oxidative stress and attenuates motor disorders following 6-OHDA induced Parkinson disease.
Topics: Animals; Disease Models, Animal; Humans; Motor Disorders; Oxidative Stress; Oxidopamine; Parkinson Disease; Parkinsonian Disorders; Peroxidase; Rats; Rats, Wistar; Substantia Nigra | 2022 |
GLUT4 mediates the protective function of gastrodin against pressure overload-induced cardiac hypertrophy.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Glucose Transporter Type 4; Insulins; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Myosin Heavy Chains | 2023 |
Effect of gastrodin against cognitive impairment and neurodegeneration in APP/PS1 mice via regulating gut microbiota-gut-brain axis.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain-Gut Axis; Cognitive Dysfunction; Disease Models, Animal; Insulin-Like Growth Factor I; Mice; Mice, Transgenic | 2023 |
Pharmacokinetic comparative study of tetramethylpyrazine and ferulic acid and their compatibility with different concentration of gastrodin and gastrodigenin on blood-stasis migraine model by blood-brain microdialysis method.
Topics: Administration, Oral; Animals; Benzyl Alcohols; Blood-Brain Barrier; Cold Temperature; Coumaric Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drugs, Chinese Herbal; Extracellular Fluid; Gastrodia; Glucosides; Humans; Ligusticum; Male; Microdialysis; Migraine Disorders; Permeability; Pyrazines; Rats; Specific Pathogen-Free Organisms; Vasoconstriction | 2020 |
Gastrodin Attenuates Neuronal Apoptosis and Neurological Deficits after Experimental Intracerebral Hemorrhage.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Behavior, Animal; Benzyl Alcohols; Brain Edema; Cells, Cultured; Cerebral Cortex; Cerebral Hemorrhage; Disease Models, Animal; Glucosides; Male; Motor Activity; Neurons; Neuroprotective Agents; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction | 2020 |
Gastrodin Alleviates Vascular Dementia in a 2-VO-Vascular Dementia Rat Model by Altering Amyloid and Tau Levels.
Topics: Amyloid beta-Peptides; Animals; Benzyl Alcohols; Brain Ischemia; Carotid Stenosis; Dementia, Vascular; Disease Models, Animal; Glucosides; Hippocampus; Male; Maze Learning; Memory; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; tau Proteins | 2020 |
Effects of gastrodin against carbon tetrachloride induced kidney inflammation and fibrosis in mice associated with the AMPK/Nrf2/HMGB1 pathway.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Benzyl Alcohols; Carbon Tetrachloride; Disease Models, Animal; Fibrosis; Glucosides; HMGB1 Protein; Inflammation; Kidney Diseases; Male; Mice; Mice, Inbred ICR; NF-E2-Related Factor 2; Phytotherapy; Protein Kinases | 2020 |
Effects of Gastrodin against Lead-Induced Brain Injury in Mice Associated with the Wnt/Nrf2 Pathway.
Topics: Animals; Benzyl Alcohols; Brain Injuries; Disease Models, Animal; Glucosides; Hippocampus; Lead; Lead Poisoning; Male; Mice; Mice, Inbred ICR; Neuroprotective Agents; NF-E2-Related Factor 2; Wnt Signaling Pathway | 2020 |
Gastrodin Pretreatment Protects Liver Against Ischemia-Reperfusion Injury via Activation of the Nrf2/HO-1 Pathway.
Topics: Animals; Antioxidants; Benzyl Alcohols; Cytokines; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Glucosides; Heme Oxygenase-1; Liver; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phytotherapy; Preoperative Care; Reperfusion Injury; Signal Transduction; Toll-Like Receptor 4 | 2020 |
Gastrodin Regulates the Notch Signaling Pathway and Sirt3 in Activated Microglia in Cerebral Hypoxic-Ischemia Neonatal Rats and in Activated BV-2 Microglia.
Topics: Animals; Animals, Newborn; Benzyl Alcohols; Carotid Artery, Common; Cells, Cultured; Cerebral Cortex; Corpus Callosum; Diamines; Disease Models, Animal; Drug Synergism; Gene Expression Regulation; Glucosides; Hypoxia-Ischemia, Brain; Ligation; Lipopolysaccharides; Microglia; Neuroinflammatory Diseases; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Notch1; Signal Transduction; Sirtuins; Thiazoles; Tumor Necrosis Factor-alpha | 2021 |
Gastrodin alleviates perioperative neurocognitive dysfunction of aged mice by suppressing neuroinflammation.
Topics: Animals; Anti-Inflammatory Agents; Behavior, Animal; Benzyl Alcohols; Cognition; Disease Models, Animal; Fear; Glucosides; Glycogen Synthase Kinase 3 beta; Hippocampus; Inflammation Mediators; Interleukin-10; Interleukin-1beta; Interleukin-6; Male; Maze Learning; Mice, Inbred C57BL; Microglia; Perioperative Period; Phosphorylation; Postoperative Cognitive Complications; tau Proteins; Tumor Necrosis Factor-alpha | 2021 |
Gastrodin alleviates seizure severity and neuronal excitotoxicities in the rat lithium-pilocarpine model of temporal lobe epilepsy via enhancing GABAergic transmission.
Topics: Animals; Anticonvulsants; Benzyl Alcohols; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Gastrodia; Glucosides; Hippocampus; Lithium; Male; Medicine, Chinese Traditional; Neurons; Neuroprotective Agents; Pilocarpine; Rats, Sprague-Dawley; Receptors, GABA-A; Rhizome; Seizures; Status Epilepticus | 2021 |
Gastrodin - A potential drug used for the treatment of Tourette Syndrome.
Topics: Animals; Benzyl Alcohols; Brain; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Gastrodia; Glucosides; Male; Molecular Imaging; Phytotherapy; Positron-Emission Tomography; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tourette Syndrome | 2021 |
Gastrodin attenuates lithium-pilocarpine-induced epilepsy by activating AMPK-mediated PPARα in a juvenile rat model.
Topics: Adenylate Kinase; Animals; Behavior, Animal; Benzyl Alcohols; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Electroencephalography; Enzyme Activation; Epilepsy; Glucosides; Lithium Compounds; Nerve Growth Factor; Pilocarpine; PPAR alpha; Rats; Rats, Sprague-Dawley; Signal Transduction | 2021 |
Gastrodin alleviates inflammatory injury of cardiomyocytes in septic shock mice via inhibiting NLRP3 expression.
Topics: Animals; Benzyl Alcohols; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Glucosides; Inflammation; Interleukin-1beta; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; NLR Family, Pyrin Domain-Containing 3 Protein; Shock, Septic | 2021 |
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Topics: Acetic Acid; Animals; Aorta; Atherosclerosis; Benzyl Alcohols; Butyric Acid; Disease Models, Animal; Drugs, Chinese Herbal; Fatty Acids, Volatile; Gastrodia; Gastrointestinal Microbiome; Glucosides; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1beta; Intestinal Mucosa; Lipids; Mice, Inbred C57BL; Propionates; Tight Junction Proteins; Tumor Necrosis Factor-alpha | 2021 |
Gastrodin extends the lifespan and protects against neurodegeneration in the Drosophila PINK1 model of Parkinson's disease.
Topics: Animals; Benzyl Alcohols; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Drugs, Chinese Herbal; Female; Gastrodia; Glucosides; Humans; Longevity; Male; Neuroprotection; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Protein Serine-Threonine Kinases | 2021 |
Gastrodin Improves Nonalcoholic Fatty Liver Disease Through Activation of the Adenosine Monophosphate-Activated Protein Kinase Signaling Pathway.
Topics: AMP-Activated Protein Kinases; Animals; Benzyl Alcohols; Diet, High-Fat; Disease Models, Animal; Glucosides; Humans; Lipid Metabolism; Male; Mice; Non-alcoholic Fatty Liver Disease; Signal Transduction | 2021 |
Gastrodin protects against LPS-induced acute lung injury by activating Nrf2 signaling pathway.
Topics: Acute Lung Injury; Animals; Benzyl Alcohols; Biomarkers; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Glucosides; Heme Oxygenase-1; Inflammation Mediators; Lipopolysaccharides; Mice; NF-E2-Related Factor 2; NF-kappa B; Peroxidase; Protective Agents; Respiratory Function Tests; Signal Transduction | 2017 |
Comparative effects of traditional Chinese and Western migraine medicines in an animal model of nociceptive trigeminovascular activation.
Topics: Animals; Benzyl Alcohols; Disease Models, Animal; Dura Mater; Glucosides; Levetiracetam; Male; Medicine, Chinese Traditional; Migraine Disorders; Neurons, Afferent; Nociceptive Pain; Pain Management; Propranolol; Pyrazines; Rats, Sprague-Dawley; Trigeminal Nerve | 2018 |
Gastrodin Protects against Ethanol-Induced Liver Injury and Apoptosis in HepG2 Cells and Animal Models of Alcoholic Liver Disease.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Benzyl Alcohols; Cell Survival; Disease Models, Animal; Ethanol; Glucosides; Hep G2 Cells; Humans; Liver; Liver Diseases, Alcoholic; Male; Membrane Potential, Mitochondrial; Mice, Inbred ICR; Protective Agents; Rats, Sprague-Dawley | 2018 |
[Effect and mechanism of gastrodin inhibiting β-amyloid plaques in brain of mice].
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzyl Alcohols; Brain; Disease Models, Animal; Glucosides; Memory; Memory Disorders; Mice; Mice, Transgenic; Plaque, Amyloid | 2016 |
Post-stroke gastrodin treatment ameliorates ischemic injury and increases neurogenesis and restores the Wnt/β-Catenin signaling in focal cerebral ischemia in mice.
Topics: Animals; Apoptosis; Benzyl Alcohols; beta Catenin; Brain; Brain Ischemia; Disease Models, Animal; Doublecortin Protein; Glucosides; Infarction, Middle Cerebral Artery; Ischemia; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neuroprotective Agents; Stroke; Wnt Signaling Pathway | 2019 |
Gastrodin attenuates neuroinflammation in DOI-induce Tourette syndrome in rats.
Topics: Amphetamines; Animals; Behavior, Animal; Benzyl Alcohols; Cytokines; Disease Models, Animal; Glucosides; Inflammation; Male; MAP Kinase Signaling System; Rats; Rats, Sprague-Dawley; Tourette Syndrome | 2019 |
Lipid Modulating Anti-oxidant Stress Activity of Gastrodin on Nonalcoholic Fatty Liver Disease Larval Zebrafish Model.
Topics: Animals; Antioxidants; Benzyl Alcohols; Disease Models, Animal; Gastrodia; Gene Expression Regulation; Glucosides; Larva; Lipid Metabolism; Non-alcoholic Fatty Liver Disease; Zebrafish | 2019 |
Gastrodin ameliorates Parkinson's disease by downregulating connexin 43.
Topics: Animals; Astrocytes; Benzyl Alcohols; Cell Communication; Connexin 43; Disease Models, Animal; Down-Regulation; Gap Junctions; Gene Expression Regulation; Glucosides; Parkinson Disease; Phosphorylation; Rats; Rotenone | 2013 |
Gastrodin ameliorates anxiety-like behaviors and inhibits IL-1beta level and p38 MAPK phosphorylation of hippocampus in the rat model of posttraumatic stress disorder.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzyl Alcohols; Disease Models, Animal; Drugs, Chinese Herbal; Glucosides; Hippocampus; Interleukin-1beta; Interleukin-6; Male; Motor Activity; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Stress Disorders, Post-Traumatic; Time Factors | 2013 |
Gastrodin ameliorates depression-like behaviors and up-regulates proliferation of hippocampal-derived neural stem cells in rats: involvement of its anti-inflammatory action.
Topics: Animals; Antidepressive Agents; Benzyl Alcohols; Cell Survival; Cells, Cultured; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Embryo, Mammalian; Food Preferences; Glucosides; Hippocampus; Male; Maze Learning; Neural Stem Cells; Rats; Stress, Psychological; Sucrose; Swimming; Up-Regulation | 2014 |
Gastrodin alleviates memory deficits and reduces neuropathology in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Benzyl Alcohols; Brain; Cytokines; Disease Models, Animal; Glucosides; Maze Learning; Memory Disorders; Mice; Mice, Transgenic; Microglia; Neuroprotective Agents; RNA, Messenger | 2014 |
Dual regulating effects of gastrodin on extracellular dopamine concentration in rats models of Tourette's syndrome.
Topics: Animals; Apomorphine; Benzyl Alcohols; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Down-Regulation; Glucosides; Haloperidol; Homovanillic Acid; Male; Nitriles; Rats; Stereotyped Behavior; Tourette Syndrome; Up-Regulation | 2015 |
Gastrodin improves cognitive dysfunction and decreases oxidative stress in vascular dementia rats induced by chronic ischemia.
Topics: Alcohol Dehydrogenase; Animals; Antioxidants; Apoptosis; Behavior, Animal; Benzyl Alcohols; Brain; Brain Ischemia; Cell Line, Tumor; Cerebrovascular Circulation; Chronic Disease; Cognition; Dementia, Vascular; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Glutathione Peroxidase; Humans; Male; Malondialdehyde; Maze Learning; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Sulfhydryl Compounds; Time Factors | 2015 |
[Effects of Electroacupuncture Intervention Combined with Gastrodin on Expression of Proteins Related to Proliferation-differentiation of Neural Stem Cells in Hippocampal CA 1 and CA 3 Regions in Focal Cerebral Ischemia Rats].
Topics: Animals; Benzyl Alcohols; Brain Ischemia; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Cell Differentiation; Cell Proliferation; Combined Modality Therapy; Disease Models, Animal; Drugs, Chinese Herbal; Electroacupuncture; Glial Fibrillary Acidic Protein; Glucosides; Humans; Male; Nestin; Neural Stem Cells; Rats; Rats, Sprague-Dawley | 2015 |
Gastrodin suppresses BACE1 expression under oxidative stress condition via inhibition of the PKR/eIF2α pathway in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Benzyl Alcohols; Cell Line, Tumor; Disease Models, Animal; eIF-2 Kinase; Glucosides; Hippocampus; Humans; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress; Signal Transduction; Spatial Memory | 2016 |
Gastrodin reversed the traumatic stress-induced depressed-like symptoms in rats.
Topics: Animals; Antidepressive Agents; Benzyl Alcohols; Brain-Derived Neurotrophic Factor; Depression; Depressive Disorder; Disease Models, Animal; Gastrodia; Glucosides; Hippocampus; Locus Coeruleus; Male; Neuropeptide Y; Norepinephrine; Phytotherapy; Plant Extracts; Rats, Sprague-Dawley; Stress Disorders, Post-Traumatic; Swimming; Tyrosine 3-Monooxygenase | 2016 |
Gastrodin Reduces the Severity of Status Epilepticus in the Rat Pilocarpine Model of Temporal Lobe Epilepsy by Inhibiting Nav1.6 Sodium Currents.
Topics: Animals; Benzyl Alcohols; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Temporal Lobe; Glucosides; Male; NAV1.6 Voltage-Gated Sodium Channel; Pilocarpine; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Sodium Channel Blockers; Status Epilepticus | 2017 |
Gastrodin ameliorates subacute phase cerebral ischemia‑reperfusion injury by inhibiting inflammation and apoptosis in rats.
Topics: Animals; Apoptosis; Benzyl Alcohols; Brain Ischemia; Caspase 3; Cyclooxygenase 2; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression Regulation; Glucosides; Humans; Inflammation; Interleukin-1beta; Nitric Oxide Synthase Type II; Rats; Reperfusion Injury | 2016 |
[Effect and mechanism of traditional Chinese herbs against Aβ expression in brain tissues of mice with Alzheimer's disease].
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Benzyl Alcohols; Brain; Disease Models, Animal; Glucosides; Hippocampus; Memory; Mice; Mice, Transgenic; Monoterpenes; Plaque, Amyloid; Random Allocation; Saponins; Triterpenes | 2016 |
Gastrodin Attenuates Pentylenetetrazole-Induced Seizures by Modulating the Mitogen-Activated Protein Kinase-Associated Inflammatory Responses in Mice.
Topics: Animals; Anti-Inflammatory Agents; Benzyl Alcohols; Convulsants; CREB-Binding Protein; Disease Models, Animal; Glucosides; Inflammation; Interleukin-10; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; Pentylenetetrazole; Seizures; Tumor Necrosis Factor-alpha | 2017 |
Formulation and evaluation of in situ gelling systems for intranasal administration of gastrodin.
Topics: Absorption; Acetic Acid; Adhesiveness; Administration, Intranasal; Animals; Anura; Benzyl Alcohols; Chemistry, Pharmaceutical; Disease Models, Animal; Drug Carriers; Drug Compounding; Drug Stability; Drugs, Chinese Herbal; Elasticity; Gels; Glucosides; Male; Nasal Mucosa; Pain; Parabens; Permeability; Polysaccharides, Bacterial; Preservatives, Pharmaceutical; Rats; Rats, Sprague-Dawley; Rheology; Sleep; Technology, Pharmaceutical; Temperature; Time Factors; Viscosity; Water | 2011 |