gastrins and Scurvy

gastrins has been researched along with Scurvy* in 1 studies

Other Studies

1 other study(ies) available for gastrins and Scurvy

Article	Year
Impaired alpha-carboxyamidation of gastrin in vitamin C-deficient guinea pigs. FEBS letters, 1986, Feb-03, Volume: 196, Issue:1 The biosynthetic activation of many hormonal peptides requires enzymatic alpha-carboxyamidation via glycine-extended intermediate forms. By specific radioimmunochemical measurement on extracts of guinea pig antra, we found that vitamin C deficiency induced a 30-fold increase in glycine-extended (i.e. inactive) gastrins. The results indicate that ascorbic acid is necessary for alpha-carboxyamidation in vivo, and thus, that the biosynthetic activation of hormonal peptides can be modified by simple dietary means. Topics: Animals; Ascorbic Acid; Diet; Gastrins; Glycine; Guinea Pigs; Peptide Fragments; Scurvy	1986

Article

Year

Impaired alpha-carboxyamidation of gastrin in vitamin C-deficient guinea pigs.

FEBS letters, 1986, Feb-03, Volume: 196, Issue:1

The biosynthetic activation of many hormonal peptides requires enzymatic alpha-carboxyamidation via glycine-extended intermediate forms. By specific radioimmunochemical measurement on extracts of guinea pig antra, we found that vitamin C deficiency induced a 30-fold increase in glycine-extended (i.e. inactive) gastrins. The results indicate that ascorbic acid is necessary for alpha-carboxyamidation in vivo, and thus, that the biosynthetic activation of hormonal peptides can be modified by simple dietary means.

Topics: Animals; Ascorbic Acid; Diet; Gastrins; Glycine; Guinea Pigs; Peptide Fragments; Scurvy

1986