gastrins and Dysentery--Bacillary

The incretory pancreatic function has been studied in 35 patients with a moderately severe course of acute dysentery. The blood plasma content of insulin, glucagon and gastrin was determined by means of radioimmunoassay with standard kits during the acute course of the disease and prior to discharge of patients. The endocrine pancreatic function was found to be deranged with an increased insulin content during convalescence; the glucagon content was decreased during the period of the disease and the gastrin content was decreased in the acute period.

Topics: Acute Disease; Adult; Dysentery, Bacillary; Gastrins; Glucagon; Humans; Insulin; Reference Values

Examination of 85 patients with acute intestinal infections (food toxoinfections of medium gravity) of non-established etiology, salmonellosis and acute dysentery) has revealed a significant increase in gastrin concentration in blood plasma both in the acute period and convalescence. The highest increase in blood plasma gastrin concentration was recorded during convalescence, particularly in patients with acute dysentery. Based on the data obtained, the conclusion is made about the involvement of gastrin in the development of gastrointestinal disorders and formation of the adaptation syndrome in acute intestinal infections.

Topics: Acute Disease; Adolescent; Adult; Dysentery, Bacillary; Gastrins; Humans; Intestine, Small; Middle Aged; Salmonella Food Poisoning; Water-Electrolyte Imbalance

Topics: Acute Disease; Adolescent; Adult; Aged; Calcium; Diarrhea; Dysentery, Bacillary; Female; Gastric Mucosa; Gastrins; Humans; Male; Middle Aged; Nucleotides, Cyclic; Shigella flexneri; Shigella sonnei; Syndrome