gastrins has been researched along with ACTH-Syndrome--Ectopic* in 3 studies
3 other study(ies) available for gastrins and ACTH-Syndrome--Ectopic
Article | Year |
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[Endocrine pancreatic tumor with Cushing syndrome and hypergastrinemia].
Topics: ACTH Syndrome, Ectopic; Adenoma, Islet Cell; Adrenocorticotropic Hormone; Combined Modality Therapy; Female; Gastrins; Humans; Hydrocortisone; Middle Aged; Neoplasm Metastasis; Pancreas; Pancreatic Neoplasms; Paraneoplastic Endocrine Syndromes | 1989 |
Suppression of ectopic adrenocorticotropin secretion by the long-acting somatostatin analog octreotide.
The long-acting somatostatin analog (octreotide) was administered to a 37-yr-old woman with the ectopic ACTH syndrome. The patient had diffuse metastatic spread of a nonpituitary tumor, presumably of pancreatic origin, and severe and rapidly progressive hypercortisolism with extreme myopathy, hypokalemia, and diabetes mellitus. Plasma ACTH and lipotropin levels and 24-h urinary cortisol excretion were greatly elevated [218 pg/mL (48 pmol/L), 1340 pg/mL (220 pmol/L), and up to 830 micrograms/24 h (2290 nmol/day), respectively]. Urinary cortisol excretion decreased to normal within 3 days after the initiation of octreotide therapy (150, 300, and 600 micrograms/day), and plasma ACTH and lipotropin levels also decreased. Urinary cortisol excretion remained normal for 2 months during chronic octreotide therapy, and her general condition improved dramatically. The only side-effect was a slight increase in the number of bowel movements. Tumor progression, however, was not controlled, and she eventually died of hepatic insufficiency. These data indicate that octreotide can be a highly effective treatment for patients with the ectopic ACTH syndrome. Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Adult; beta-Lipotropin; Female; Gastrins; Humans; Hydrocortisone; Neoplasms, Unknown Primary; Octreotide; Pancreatic Neoplasms; Paraneoplastic Endocrine Syndromes; Saliva; Somatostatin | 1989 |
Ectopic production of multiple hormones (ACTH, MSH and gastrin) by a single malignant tumor.
Topics: ACTH Syndrome, Ectopic; Adenoma, Islet Cell; Adrenocorticotropic Hormone; Adult; Fatal Outcome; Female; Gastrins; Humans; Islets of Langerhans; Melanocyte-Stimulating Hormones; Neoplasms; Neuroendocrine Tumors; Pancreatic Neoplasms | 1965 |