ganglioside--gd1a has been researched along with Paralysis* in 1 studies
1 other study(ies) available for ganglioside--gd1a and Paralysis
| Article | Year |
|---|---|
Antibodies to human myelin proteins and gangliosides in patients with acute neuroparalytic accidents induced by brain-derived rabies vaccine.
Antibody responses to myelin antigens were analysed in 15 patients who developed acute neuroparalytic accidents (ANPA) during post-exposure rabies vaccination using a rabies vaccine prepared on brain tissues and in 30 individuals who were uneventfully vaccinated. High titers (> or = 100) of IgG and IgM antibodies to GM1 or GD1a gangliosides were detected by enzyme linked immunosorbent-assay (ELISA) in plasmas from ANPA patients but not in controls. These data suggest that antibodies to GM1 and GD1a gangliosides may play a pathogenic role in the demyelinating and/or inflammatory processes characteristic of rabies vaccine-induced acute neurologic complications. Topics: Adult; Antibodies, Viral; Brain Chemistry; Child; Chromatography, High Pressure Liquid; Encephalomyelitis, Acute Disseminated; Enzyme-Linked Immunosorbent Assay; G(M1) Ganglioside; Gangliosides; Humans; Immunoglobulin G; Immunoglobulin M; Male; Middle Aged; Myelin Proteins; Paralysis; Rabies | 1998 |