gamma-sitosterol and Exocrine-Pancreatic-Insufficiency

gamma-sitosterol has been researched along with Exocrine-Pancreatic-Insufficiency* in 1 studies

Other Studies

1 other study(ies) available for gamma-sitosterol and Exocrine-Pancreatic-Insufficiency

ArticleYear
Severe Genotype, Pancreatic Insufficiency and Low Dose of Pancreatic Enzymes Associate with Abnormal Serum Sterol Profile in Cystic Fibrosis.
    Biomolecules, 2021, 02-19, Volume: 11, Issue:2

    Several factors could lead to lipid disturbances observed in cystic fibrosis (CF). This study aimed to assess sterol homeostasis in CF and define potential exogenous and endogenous determinants of lipid dysregulation.. The study involved 55 CF patients and 45 healthy subjects (HS). Sterol concentrations (μg/dL) were measured by gas chromatography/mass spectrometry. CF was characterised by lung function, pancreatic status, liver disease and diabetes coexistence,. Independent determinants of lipid status suggest that malabsorption and pancreatic enzyme supplementation play a significant role in sterol abnormalities. The measurement of campesterol and β-sitosterol concentrations in CF patients may serve for the assessment of the effectiveness of pancreatic enzyme replacement therapy and/or compliance, but further research is required.

    Topics: Adolescent; Adult; Anthropometry; Cholesterol; Cystic Fibrosis; Enzyme Replacement Therapy; Exocrine Pancreatic Insufficiency; Female; Gas Chromatography-Mass Spectrometry; Genotype; Homeostasis; Humans; Lipids; Male; Middle Aged; Pancreas; Phytosterols; Sitosterols; Sterols; Young Adult

2021