gamma-linolenic-acid and Spondylitis--Ankylosing

The genetic setting and immunopathogenesis of patients with ankylosing spondylitis can not be changed by the diet. Therefore, an effective pharmacological therapy always is required. As adjuvant therapy the anti-inflammatory diet can help to reduce inflammatory processes, and to delay flares of the disease. The anti-inflammatory diet is consistent with a balanced diet and prevents infirmity provoked by malnutrition. Ankylosing spondylitis is an autoimmune disease and, as such, nutrients may mimic an antigen and cause flares of the disease and increase disease activity driven by antigen reaction. This nutrient-receptor interaction occurs in the individual patient, necessitating an individual dietary counselling for the patient with ankylosing spondylitis.

Topics: Antioxidants; Arachidonic Acid; Autoimmune Diseases; Cross Reactions; Eicosanoids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Food Hypersensitivity; gamma-Linolenic Acid; Glutathione Peroxidase; Humans; Nutrition Assessment; Selenium; Spondylitis, Ankylosing; Vitamin E