gamma-linolenic-acid and Pre-Eclampsia

gamma-linolenic-acid has been researched along with Pre-Eclampsia* in 2 studies

Trials

2 trial(s) available for gamma-linolenic-acid and Pre-Eclampsia

Article	Year
Dietary supplementation with primrose oil or fish oil does not change urinary excretion of prostacyclin and thromboxane metabolites in pre-eclamptic women. Prostaglandins, leukotrienes, and essential fatty acids, 1993, Volume: 49, Issue:3 To study whether balance between antiaggregatory, vasodilatory prostacyclin (PGI2) and proaggregatory, vasoconstrictory thromboxane A2 (TXA2) could be affected by dietary manipulation, 18 pre-eclamptic women were treated in randomized order between 31 and 36 weeks of gestation either with primrose oil (n = 7), with fish oil (n = 5), or with placebo (n = 6). Urinary excretions of the degradation products of PGI2 (6-keto-PGF1 alpha, 2,3-dinor-6-keto-PGF1 alpha) and TXA2 (TXB2, 2,3-dinor-TXB2) were measured in 24 h urines before and serially during the supplementation. Fatty acid supplementation did not affect urinary prostanoid excretions or clinical signs of pre-eclampsia. Topics: Epoprostenol; Fatty Acids, Essential; Female; Fish Oils; gamma-Linolenic Acid; Humans; Linoleic Acids; Oenothera biennis; Plant Oils; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Thromboxane A2	1993
Attempts at dietary alteration of prostaglandin pathways in the management of pre-eclampsia. Prostaglandins, leukotrienes, and essential fatty acids, 1989, Volume: 37, Issue:3 It has been suggested that dietary supplementation with prostaglandin precursors may enhance the synthesis of PGE which lowers vascular sensitivity to increased levels of angiotensin II in pregnancy. Therefore the effect of dietary supplementation with evening primrose oil (linoleic acid and gamma-linoleic acid) in African primigravidae with established pre-eclampsia was studied. Patients were randomly allocated to one of two groups. Group A (23 patients) received 8 capsules/day of evening primrose oil and group B (24 patients) received 8 capsules of placebo. No significant differences were found between the groups in respect to perinatal outcome, blood pressure lowering effect and haematological indices. Topics: Adolescent; Adult; Blood Pressure; Diet; Fatty Acids, Essential; Female; gamma-Linolenic Acid; Humans; Linoleic Acids; Oenothera biennis; Plant Oils; Pre-Eclampsia; Pregnancy; Pregnancy Outcome	1989

Article

Year

Dietary supplementation with primrose oil or fish oil does not change urinary excretion of prostacyclin and thromboxane metabolites in pre-eclamptic women.

Prostaglandins, leukotrienes, and essential fatty acids, 1993, Volume: 49, Issue:3

To study whether balance between antiaggregatory, vasodilatory prostacyclin (PGI2) and proaggregatory, vasoconstrictory thromboxane A2 (TXA2) could be affected by dietary manipulation, 18 pre-eclamptic women were treated in randomized order between 31 and 36 weeks of gestation either with primrose oil (n = 7), with fish oil (n = 5), or with placebo (n = 6). Urinary excretions of the degradation products of PGI2 (6-keto-PGF1 alpha, 2,3-dinor-6-keto-PGF1 alpha) and TXA2 (TXB2, 2,3-dinor-TXB2) were measured in 24 h urines before and serially during the supplementation. Fatty acid supplementation did not affect urinary prostanoid excretions or clinical signs of pre-eclampsia.

Topics: Epoprostenol; Fatty Acids, Essential; Female; Fish Oils; gamma-Linolenic Acid; Humans; Linoleic Acids; Oenothera biennis; Plant Oils; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Thromboxane A2

1993

Attempts at dietary alteration of prostaglandin pathways in the management of pre-eclampsia.

Prostaglandins, leukotrienes, and essential fatty acids, 1989, Volume: 37, Issue:3

It has been suggested that dietary supplementation with prostaglandin precursors may enhance the synthesis of PGE which lowers vascular sensitivity to increased levels of angiotensin II in pregnancy. Therefore the effect of dietary supplementation with evening primrose oil (linoleic acid and gamma-linoleic acid) in African primigravidae with established pre-eclampsia was studied. Patients were randomly allocated to one of two groups. Group A (23 patients) received 8 capsules/day of evening primrose oil and group B (24 patients) received 8 capsules of placebo. No significant differences were found between the groups in respect to perinatal outcome, blood pressure lowering effect and haematological indices.

Topics: Adolescent; Adult; Blood Pressure; Diet; Fatty Acids, Essential; Female; gamma-Linolenic Acid; Humans; Linoleic Acids; Oenothera biennis; Plant Oils; Pre-Eclampsia; Pregnancy; Pregnancy Outcome

1989