Page last updated: 2024-10-18

gamma-butyrobetaine and Heart Failure

gamma-butyrobetaine has been researched along with Heart Failure in 2 studies

4-(trimethylammonio)butanoate : An amino-acid betaine gamma-aminobutyric acid zwitterion in which all of the hydrogens attached to the nitrogen are replaced by methyl groups.

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Carnitine has been associated with cardiac energy metabolism and heart failure, but the association between its precursors-trimethyllysine (TML) and γ-butyrobetaine (GBB)-and heart failure with preserved ejection fraction (HFpEF) remains unclear."8.12Association of Systemic Trimethyllysine With Heart Failure With Preserved Ejection Fraction and Cardiovascular Events. ( Dong, E; Gao, J; Huang, M; Ji, L; Li, C; Wang, DW; Wang, Y; Wei, H; Wu, J; Zhang, Q; Zhao, C; Zhao, M; Zheng, L, 2022)
"Carnitine has been associated with cardiac energy metabolism and heart failure, but the association between its precursors-trimethyllysine (TML) and γ-butyrobetaine (GBB)-and heart failure with preserved ejection fraction (HFpEF) remains unclear."4.12Association of Systemic Trimethyllysine With Heart Failure With Preserved Ejection Fraction and Cardiovascular Events. ( Dong, E; Gao, J; Huang, M; Ji, L; Li, C; Wang, DW; Wang, Y; Wei, H; Wu, J; Zhang, Q; Zhao, C; Zhao, M; Zheng, L, 2022)
"Trimethylamine N-oxide (TMAO), a gut-related metabolite, is associated with heart failure (HF) outcomes."4.02Association of gut-related metabolites with outcome in acute heart failure. ( Bernieh, D; Cassambai, S; Heaney, LM; Israr, MZ; Jones, DJL; Ng, LL; Salzano, A; Suzuki, T; Yazaki, Y, 2021)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (100.00)2.80

Authors

AuthorsStudies
Wei, H1
Zhao, M1
Wu, J1
Li, C1
Huang, M1
Gao, J1
Zhang, Q1
Ji, L1
Wang, Y1
Zhao, C1
Dong, E1
Zheng, L1
Wang, DW1
Israr, MZ1
Bernieh, D1
Salzano, A1
Cassambai, S1
Yazaki, Y1
Heaney, LM1
Jones, DJL1
Ng, LL1
Suzuki, T1

Other Studies

2 other studies available for gamma-butyrobetaine and Heart Failure

ArticleYear
Association of Systemic Trimethyllysine With Heart Failure With Preserved Ejection Fraction and Cardiovascular Events.
    The Journal of clinical endocrinology and metabolism, 2022, 11-25, Volume: 107, Issue:12

    Topics: Carnitine; Cross-Sectional Studies; Heart Failure; Humans; Prospective Studies; Stroke Volume

2022
Association of gut-related metabolites with outcome in acute heart failure.
    American heart journal, 2021, Volume: 234

    Topics: Acetylcarnitine; Acute Disease; Aged; Aged, 80 and over; Betaine; Carnitine; Choline; Female; Gastro

2021