Page last updated: 2024-10-18

gamma-butyrobetaine and Cardiovascular Stroke

gamma-butyrobetaine has been researched along with Cardiovascular Stroke in 4 studies

4-(trimethylammonio)butanoate : An amino-acid betaine gamma-aminobutyric acid zwitterion in which all of the hydrogens attached to the nitrogen are replaced by methyl groups.

Research Excerpts

ExcerptRelevanceReference
" In conclusion, our study, for the first time, provides experimental evidence that the long-term administration of mildronate not only decreases free carnitine concentration, but also causes a significant increase in GBB concentration, which correlates with the cardioprotection of mildronate."1.33Mildronate, an inhibitor of carnitine biosynthesis, induces an increase in gamma-butyrobetaine contents and cardioprotection in isolated rat heart infarction. ( Dambrova, M; Kalvinsh, I; Kirjanova, O; Liepinsh, E; Loca, D; Pugovichs, O; Vilskersts, R, 2006)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Skagen, K1
Trøseid, M1
Ueland, T1
Holm, S1
Abbas, A1
Gregersen, I1
Kummen, M1
Bjerkeli, V1
Reier-Nilsen, F1
Russell, D1
Svardal, A1
Karlsen, TH1
Aukrust, P1
Berge, RK1
Hov, JE1
Halvorsen, B1
Skjelland, M1
Kuka, J2
Makrecka-Kuka, M1
Cirule, H2
Grinberga, S1
Sevostjanovs, E1
Dambrova, M3
Liepinsh, E3
Vilskersts, R2
Makrecka, M1
Pugovics, O1
Kalvinsh, I2
Loca, D1
Kirjanova, O1
Pugovichs, O1

Other Studies

4 other studies available for gamma-butyrobetaine and Cardiovascular Stroke

ArticleYear
The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis.
    Atherosclerosis, 2016, Volume: 247

    Topics: Aged; Betaine; Biomarkers; Carnitine; Carotid Stenosis; Case-Control Studies; Cause of Death; Chroma

2016
Decrease in Long-Chain Acylcarnitine Tissue Content Determines the Duration of and Correlates with the Cardioprotective Effect of Methyl-GBB.
    Basic & clinical pharmacology & toxicology, 2017, Volume: 121, Issue:2

    Topics: Animals; Betaine; Biotransformation; Cardiotonic Agents; Carnitine; Down-Regulation; gamma-Aminobuty

2017
The cardioprotective effect of mildronate is diminished after co-treatment with L-carnitine.
    Journal of cardiovascular pharmacology and therapeutics, 2012, Volume: 17, Issue:2

    Topics: Animals; Betaine; Cardiovascular Agents; Carnitine; Carnitine O-Palmitoyltransferase; Chromatography

2012
Mildronate, an inhibitor of carnitine biosynthesis, induces an increase in gamma-butyrobetaine contents and cardioprotection in isolated rat heart infarction.
    Journal of cardiovascular pharmacology, 2006, Volume: 48, Issue:6

    Topics: Animals; Betaine; Cardiovascular Agents; Carnitine; Chromatography, High Pressure Liquid; Coronary C

2006