gamma-aminobutyric acid has been researched along with Tics in 7 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Tics: Habitual, repeated, rapid contraction of certain muscles, resulting in stereotyped individualized actions that can be voluntarily suppressed for only brief periods. They often involve the face, vocal cords, neck, and less often the extremities. Examples include repetitive throat clearing, vocalizations, sniffing, pursing the lips, and excessive blinking. Tics tend to be aggravated by emotional stress. When frequent they may interfere with speech and INTERPERSONAL RELATIONS. Conditions which feature frequent and prominent tics as a primary manifestation of disease are referred to as TIC DISORDERS. (From Adams et al., Principles of Neurology, 6th ed, pp109-10)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Many studies have indicated that a variety of neurotransmitters are implicated in the pathophysiology of Tourette syndrome (TS), including dopamine (DA), serotonin (5-TH), homovanillic acid (HVA), and gamma-amino butyric acid (GABA)." | 5.16 | Effects of Chinese herbal medicine Ningdong granule on regulating dopamine (DA)/serotonin (5-TH) and gamma-amino butyric acid (GABA) in patients with Tourette syndrome. ( Li, A; Li, J; Qi, F; Wang, S; Zhao, L, 2012) |
| "Stuttering was identified in 23." | 2.79 | [Comorbidity of tics and stuttering]. ( Aitbekov, KA; Bondarchuk, YI; Chutko, LS; Nikishena, IS; Surushkina, SY, 2014) |
| "Authors examined 181 children with tics, aged 7-13." | 2.79 | [Comorbidity of tics and stuttering]. ( Aitbekov, KA; Bondarchuk, YI; Chutko, LS; Nikishena, IS; Surushkina, SY, 2014) |
| "We found that NDG could ameliorate tics significantly according the YGTSS score." | 2.77 | Effects of Chinese herbal medicine Ningdong granule on regulating dopamine (DA)/serotonin (5-TH) and gamma-amino butyric acid (GABA) in patients with Tourette syndrome. ( Li, A; Li, J; Qi, F; Wang, S; Zhao, L, 2012) |
| "Tics are the essential component of a variety of disorders, notably Tourette syndrome." | 2.41 | The treatment of tics. ( Singer, HS, 2001) |
| "Because the mere presence of tics does not require therapeutic intervention, criteria are essential for determining a functional disability." | 2.41 | The treatment of tics. ( Singer, HS, 2001) |
| "More severe urges correlate with worse tics and can render behavioral therapies less effective." | 1.91 | From urges to tics in children with Tourette syndrome: associations with supplementary motor area GABA and right motor cortex physiology. ( Cecil, KM; Edden, RAE; Gilbert, DL; Horn, PS; Huddleston, DA; Jackson, HS; Larsh, TR; Mostofsky, SH; Wu, SW, 2023) |
| "In orthostatic test, patients with Tourette syndrome demonstrated an unfavorable hypersympathicotonic type of cardiovascular system reaction." | 1.33 | [Autonomic cardiovascular regulation in patients with tics and Tourette syndrome]. ( Begasheva, OI; Kabanova, SA; Komarova, IB; Nazarova, EK; Zykov, VP, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| He, JL | 1 |
| Mikkelsen, M | 1 |
| Huddleston, DA | 2 |
| Crocetti, D | 1 |
| Cecil, KM | 2 |
| Singer, HS | 2 |
| Edden, RAE | 2 |
| Gilbert, DL | 2 |
| Mostofsky, SH | 2 |
| Puts, NAJ | 1 |
| Larsh, TR | 1 |
| Horn, PS | 1 |
| Wu, SW | 1 |
| Jackson, HS | 1 |
| Surushkina, SY | 1 |
| Chutko, LS | 1 |
| Aitbekov, KA | 1 |
| Nikishena, IS | 1 |
| Bondarchuk, YI | 1 |
| Wang, S | 1 |
| Qi, F | 1 |
| Li, J | 1 |
| Zhao, L | 1 |
| Li, A | 1 |
| Zykov, VP | 1 |
| Komarova, IB | 1 |
| Nazarova, EK | 1 |
| Begasheva, OI | 1 |
| Kabanova, SA | 1 |
| Leckman, JF | 1 |
| Riddle, MA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-Blind, Placebo-Controlled Trial Evaluating the Efficacy and Safety of Yi-Gan San in Children and Adolescents With Tourette's Disorder[NCT03564132] | Phase 2 | 38 participants (Actual) | Interventional | 2018-06-16 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for gamma-aminobutyric acid and Tics
| Article | Year |
|---|---|
Tourette's syndrome: when habit-forming systems form habits of their own?
Topics: Animals; Autoimmunity; Basal Ganglia; Cerebral Cortex; Disease Models, Animal; gamma-Aminobutyric Ac | 2000 |
The treatment of tics.
Topics: Adrenergic alpha-Agonists; Androgen Antagonists; Anti-Bacterial Agents; Antipsychotic Agents; Autoim | 2001 |
2 trials available for gamma-aminobutyric acid and Tics
| Article | Year |
|---|---|
[Comorbidity of tics and stuttering].
Topics: Adolescent; Anticonvulsants; Child; Comorbidity; Female; gamma-Aminobutyric Acid; Humans; Male; Stut | 2014 |
Effects of Chinese herbal medicine Ningdong granule on regulating dopamine (DA)/serotonin (5-TH) and gamma-amino butyric acid (GABA) in patients with Tourette syndrome.
Topics: Adolescent; Child; Dopamine; Drugs, Chinese Herbal; Enzyme-Linked Immunosorbent Assay; Female; gamma | 2012 |
3 other studies available for gamma-aminobutyric acid and Tics
| Article | Year |
|---|---|
Frequency and Intensity of Premonitory Urges-to-Tic in Tourette Syndrome Is Associated With Supplementary Motor Area GABA+ Levels.
Topics: Child; Child, Preschool; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Infant; Motor Cortex; Senso | 2022 |
From urges to tics in children with Tourette syndrome: associations with supplementary motor area GABA and right motor cortex physiology.
Topics: Child; Child, Preschool; gamma-Aminobutyric Acid; Humans; Inhibition, Psychological; Motor Cortex; T | 2023 |
[Autonomic cardiovascular regulation in patients with tics and Tourette syndrome].
Topics: Anti-Dyskinesia Agents; Anticonvulsants; Autonomic Nervous System Diseases; Child; Clonazepam; Femal | 2005 |