gamma-aminobutyric acid has been researched along with TDP-43 Proteinopathies in 1 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
TDP-43 Proteinopathies: Diseases characterized by the presence of abnormally phosphorylated, ubiquitinated, and cleaved DNA-binding protein TDP-43 in affected brain and spinal cord. Inclusions of the pathologic protein in neurons and glia, without the presence of AMYLOID, is the major feature of these conditions, thus making these proteinopathies distinct from most other neurogenerative disorders in which protein misfolding leads to brain amyloidosis. Both frontotemporal lobar degeneration and AMYOTROPHIC LATERAL SCLEROSIS exhibit this common method of pathogenesis and thus they may represent two extremes of a continuous clinicopathological spectrum of one disease.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hebron, M | 1 |
| Chen, W | 1 |
| Miessau, MJ | 1 |
| Lonskaya, I | 1 |
| Moussa, CE | 1 |
1 other study available for gamma-aminobutyric acid and TDP-43 Proteinopathies
| Article | Year |
|---|---|
Parkin reverses TDP-43-induced cell death and failure of amino acid homeostasis.
Topics: Amino Acids; Animals; Blotting, Western; Carrier Proteins; Caspase 3; Cell Death; Citric Acid Cycle; | 2014 |