gamma-aminobutyric acid has been researched along with Supranuclear Palsy, Progressive in 7 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Supranuclear Palsy, Progressive: A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Murley, AG | 2 |
| Rouse, MA | 2 |
| Jones, PS | 1 |
| Ye, R | 1 |
| Hezemans, FH | 1 |
| O'Callaghan, C | 1 |
| Frangou, P | 1 |
| Kourtzi, Z | 1 |
| Rua, C | 1 |
| Carpenter, TA | 1 |
| Rodgers, CT | 1 |
| Rowe, JB | 2 |
| Adams, NE | 1 |
| Hughes, LE | 1 |
| Phillips, HN | 1 |
| Shaw, AD | 1 |
| Cope, TE | 1 |
| Bevan-Jones, WR | 1 |
| Passamonti, L | 1 |
| Street, D | 1 |
| Holland, N | 1 |
| Nesbitt, D | 1 |
| Friston, K | 1 |
| Bonnet, C | 1 |
| Rusz, J | 1 |
| Hanuška, J | 1 |
| Dezortová, M | 1 |
| Jírů, F | 1 |
| Sieger, T | 1 |
| Jech, R | 1 |
| Klempíř, J | 1 |
| Roth, J | 1 |
| Bezdíček, O | 1 |
| Serranová, T | 1 |
| Dušek, P | 1 |
| Uher, T | 1 |
| Flammand-Roze, C | 1 |
| Hájek, M | 1 |
| Růžička, E | 1 |
| Oskarsson, B | 1 |
| Pelak, V | 1 |
| Quan, D | 1 |
| Hall, D | 1 |
| Foster, C | 1 |
| Galetta, S | 1 |
| Poujois, A | 1 |
| Vidailhet, M | 1 |
| Trocello, JM | 1 |
| Bourdain, F | 1 |
| Gaymard, B | 1 |
| Rivaud-Péchoux, S | 1 |
| Levy, R | 1 |
| Ruberg, M | 2 |
| Herrero, MT | 1 |
| Villares, J | 1 |
| Javoy-Agid, F | 2 |
| Agid, Y | 2 |
| Hirsch, EC | 1 |
| Pillon, B | 1 |
| Dubois, B | 1 |
| Duyckaerts, C | 1 |
| Hauw, JJ | 1 |
| Baron, JC | 1 |
| Scatton, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Oral Gabapentin and Pregabalin in Postoperative Pain Control After Photorefractive Keratectomy: a Prospective, Randomized Study.[NCT00954187] | 8 participants (Actual) | Interventional | 2009-11-30 | Terminated (stopped due to PI left institution) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for gamma-aminobutyric acid and Supranuclear Palsy, Progressive
| Article | Year |
|---|---|
GABAergic cortical network physiology in frontotemporal lobar degeneration.
Topics: Aged; Cerebral Cortex; Cross-Over Studies; Double-Blind Method; Female; Frontotemporal Dementia; GAB | 2021 |
Effect of gabapentin on oculomotor control and parkinsonism in patients with progressive supranuclear palsy.
Topics: Aged; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Eye Movements; Female; Gabapentin; | 2007 |
5 other studies available for gamma-aminobutyric acid and Supranuclear Palsy, Progressive
| Article | Year |
|---|---|
GABA and glutamate deficits from frontotemporal lobar degeneration are associated with disinhibition.
Topics: Aged; Aged, 80 and over; Female; Frontotemporal Lobar Degeneration; gamma-Aminobutyric Acid; Glutama | 2020 |
GABA spectra and remote distractor effect in progressive supranuclear palsy: A pilot study.
Topics: Aged; Eye Movements; Female; gamma-Aminobutyric Acid; Healthy Volunteers; Humans; Magnetic Resonance | 2017 |
Stiff eyes in stiff-person syndrome.
Topics: Autoantibodies; Diagnosis, Differential; Disease Progression; Electromyography; Female; gamma-Aminob | 2008 |
Alterations of GABAergic neurons in the basal ganglia of patients with progressive supranuclear palsy: an in situ hybridization study of GAD67 messenger RNA.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Autopsy; Brain; Caudate Nucleus; gamma-Aminobutyric A | 1995 |
Progressive supranuclear palsy: anatomoclinical and biochemical considerations.
Topics: Aged; Blood Glucose; Brain; Choline O-Acetyltransferase; Frontal Lobe; gamma-Aminobutyric Acid; Huma | 1987 |