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gamma-aminobutyric acid and Subarachnoid Hemorrhage

gamma-aminobutyric acid has been researched along with Subarachnoid Hemorrhage in 6 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.

Research Excerpts

ExcerptRelevanceReference
"To measure concentrations of glutamate, aspartate, γ-aminobutyric acid (GABA), and glycine in CSF of dogs with experimentally induced subarachnoid hemorrhage (SAH) and to assess effects of cyclosporine and simvastatin on these concentrations."9.17Effect of treatment with simvastatin and cyclosporine on neurotransmitter concentrations in cerebrospinal fluid after subarachnoid hemorrhage in dogs. ( Bulsara, KR; Coates, JR; Edwards, GL; Eifler, DM; Kent, M; Platt, SR, 2013)
" However, narcotics can have significant adverse effects."5.42Safety and tolerability of gabapentin for aneurysmal subarachnoid hemorrhage (sah) headache and meningismus. ( Dhakal, LP; Freeman, WD; Hodge, DO; Mayes, M; Nagal, J; Nagel, J; Ng, LK; Richie, A, 2015)
"GBP appears to be relatively safe and tolerable in SAH patients with headache and may be a useful narcotic-sparing agent to prevent narcotics-associated complications, such as gastrointestinal immobility, ileus, and constipation."5.42Safety and tolerability of gabapentin for aneurysmal subarachnoid hemorrhage (sah) headache and meningismus. ( Dhakal, LP; Freeman, WD; Hodge, DO; Mayes, M; Nagal, J; Nagel, J; Ng, LK; Richie, A, 2015)
" GBP dosing was rapidly escalated within days of SAH up to a median of 1,200 mg/day, with a range of 300 mg three times a day to 900 mg three times a day."5.42Safety and tolerability of gabapentin for aneurysmal subarachnoid hemorrhage (sah) headache and meningismus. ( Dhakal, LP; Freeman, WD; Hodge, DO; Mayes, M; Nagal, J; Nagel, J; Ng, LK; Richie, A, 2015)
"Severe headache was observed in all SAH patients."5.42Safety and tolerability of gabapentin for aneurysmal subarachnoid hemorrhage (sah) headache and meningismus. ( Dhakal, LP; Freeman, WD; Hodge, DO; Mayes, M; Nagal, J; Nagel, J; Ng, LK; Richie, A, 2015)
"Headache after aneurysmal subarachnoid hemorrhage (SAH) is very common and is often described as the "worst headache imaginable."5.42Safety and tolerability of gabapentin for aneurysmal subarachnoid hemorrhage (sah) headache and meningismus. ( Dhakal, LP; Freeman, WD; Hodge, DO; Mayes, M; Nagal, J; Nagel, J; Ng, LK; Richie, A, 2015)
"To measure concentrations of glutamate, aspartate, γ-aminobutyric acid (GABA), and glycine in CSF of dogs with experimentally induced subarachnoid hemorrhage (SAH) and to assess effects of cyclosporine and simvastatin on these concentrations."5.17Effect of treatment with simvastatin and cyclosporine on neurotransmitter concentrations in cerebrospinal fluid after subarachnoid hemorrhage in dogs. ( Bulsara, KR; Coates, JR; Edwards, GL; Eifler, DM; Kent, M; Platt, SR, 2013)
" However, narcotics can have significant adverse effects."1.42Safety and tolerability of gabapentin for aneurysmal subarachnoid hemorrhage (sah) headache and meningismus. ( Dhakal, LP; Freeman, WD; Hodge, DO; Mayes, M; Nagal, J; Nagel, J; Ng, LK; Richie, A, 2015)
"GBP appears to be relatively safe and tolerable in SAH patients with headache and may be a useful narcotic-sparing agent to prevent narcotics-associated complications, such as gastrointestinal immobility, ileus, and constipation."1.42Safety and tolerability of gabapentin for aneurysmal subarachnoid hemorrhage (sah) headache and meningismus. ( Dhakal, LP; Freeman, WD; Hodge, DO; Mayes, M; Nagal, J; Nagel, J; Ng, LK; Richie, A, 2015)
" GBP dosing was rapidly escalated within days of SAH up to a median of 1,200 mg/day, with a range of 300 mg three times a day to 900 mg three times a day."1.42Safety and tolerability of gabapentin for aneurysmal subarachnoid hemorrhage (sah) headache and meningismus. ( Dhakal, LP; Freeman, WD; Hodge, DO; Mayes, M; Nagal, J; Nagel, J; Ng, LK; Richie, A, 2015)
"Severe headache was observed in all SAH patients."1.42Safety and tolerability of gabapentin for aneurysmal subarachnoid hemorrhage (sah) headache and meningismus. ( Dhakal, LP; Freeman, WD; Hodge, DO; Mayes, M; Nagal, J; Nagel, J; Ng, LK; Richie, A, 2015)
"Headache after aneurysmal subarachnoid hemorrhage (SAH) is very common and is often described as the "worst headache imaginable."1.42Safety and tolerability of gabapentin for aneurysmal subarachnoid hemorrhage (sah) headache and meningismus. ( Dhakal, LP; Freeman, WD; Hodge, DO; Mayes, M; Nagal, J; Nagel, J; Ng, LK; Richie, A, 2015)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Liu, C3
He, P3
Guo, Y3
Tian, Q3
Wang, J3
Wang, G3
Zhang, Z3
Li, M3
Platt, SR1
Coates, JR1
Eifler, DM1
Edwards, GL1
Kent, M1
Bulsara, KR1
Dhakal, LP1
Hodge, DO1
Nagel, J1
Nagal, J1
Mayes, M1
Richie, A1
Ng, LK1
Freeman, WD1
Zhang, L1
Jin, J1
Yao, J1
Yue, Z1
Wei, Y1
Yang, W1
Fu, S1
Li, W1
Nascimento-Alves, P1
Fernandes-Silva, H1
Aragão-Homem, C1
Geraldes, R1
Fonseca, AC1
Hutchinson, PJ1
O'Connell, MT1
Al-Rawi, PG1
Kett-White, CR1
Gupta, AK1
Maskell, LB1
Pickard, JD1
Kirkpatrick, PJ1

Trials

1 trial available for gamma-aminobutyric acid and Subarachnoid Hemorrhage

ArticleYear
Effect of treatment with simvastatin and cyclosporine on neurotransmitter concentrations in cerebrospinal fluid after subarachnoid hemorrhage in dogs.
    American journal of veterinary research, 2013, Volume: 74, Issue:8

    Topics: Animals; Cyclosporine; Dog Diseases; Dogs; Female; gamma-Aminobutyric Acid; Glutamic Acid; Hydroxyme

2013

Other Studies

5 other studies available for gamma-aminobutyric acid and Subarachnoid Hemorrhage

ArticleYear
Taurine attenuates neuronal ferroptosis by regulating GABA
    Free radical biology & medicine, 2022, 11-20, Volume: 193, Issue:Pt 2

    Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta;

2022
Taurine attenuates neuronal ferroptosis by regulating GABA
    Free radical biology & medicine, 2022, 11-20, Volume: 193, Issue:Pt 2

    Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta;

2022
Taurine attenuates neuronal ferroptosis by regulating GABA
    Free radical biology & medicine, 2022, 11-20, Volume: 193, Issue:Pt 2

    Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta;

2022
Taurine attenuates neuronal ferroptosis by regulating GABA
    Free radical biology & medicine, 2022, 11-20, Volume: 193, Issue:Pt 2

    Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta;

2022
Taurine attenuates neuronal ferroptosis by regulating GABA
    Free radical biology & medicine, 2022, 11-20, Volume: 193, Issue:Pt 2

    Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta;

2022
Taurine attenuates neuronal ferroptosis by regulating GABA
    Free radical biology & medicine, 2022, 11-20, Volume: 193, Issue:Pt 2

    Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta;

2022
Taurine attenuates neuronal ferroptosis by regulating GABA
    Free radical biology & medicine, 2022, 11-20, Volume: 193, Issue:Pt 2

    Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta;

2022
Taurine attenuates neuronal ferroptosis by regulating GABA
    Free radical biology & medicine, 2022, 11-20, Volume: 193, Issue:Pt 2

    Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta;

2022
Taurine attenuates neuronal ferroptosis by regulating GABA
    Free radical biology & medicine, 2022, 11-20, Volume: 193, Issue:Pt 2

    Topics: beta Catenin; Brain Injuries; Ferroptosis; gamma-Aminobutyric Acid; Glycogen Synthase Kinase 3 beta;

2022
Safety and tolerability of gabapentin for aneurysmal subarachnoid hemorrhage (sah) headache and meningismus.
    Neurocritical care, 2015, Volume: 22, Issue:3

    Topics: Adult; Aged; Amines; Analgesics; Aneurysm, Ruptured; Cyclohexanecarboxylic Acids; Female; Gabapentin

2015
Effects of Propofol on Excitatory and Inhibitory Amino Acid Neurotransmitter Balance in Rats with Neurogenic Pulmonary Edema Induced by Subarachnoid Hemorrhage.
    Neurocritical care, 2016, Volume: 24, Issue:3

    Topics: Animals; Brain; Brain Edema; Disease Models, Animal; Excitatory Amino Acids; gamma-Aminobutyric Acid

2016
IV and V cranial nerves dysfunction as initial manifestations of superficial siderosis of the central nervous system.
    Revista de neurologia, 2016, Apr-01, Volume: 62, Issue:7

    Topics: Aged; Amines; Angiography, Digital Subtraction; Atrophy; Central Nervous System Diseases; Cerebellum

2016
Increases in GABA concentrations during cerebral ischaemia: a microdialysis study of extracellular amino acids.
    Journal of neurology, neurosurgery, and psychiatry, 2002, Volume: 72, Issue:1

    Topics: Adolescent; Adult; Brain; Brain Ischemia; Catheters, Indwelling; Chromatography, High Pressure Liqui

2002