gamma-aminobutyric acid has been researched along with Spinal Muscular Atrophies of Childhood in 7 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Spinal Muscular Atrophies of Childhood: A group of recessive inherited diseases that feature progressive muscular atrophy and hypotonia. They are classified as type I (Werdnig-Hoffman disease), type II (intermediate form), and type III (Kugelberg-Welander disease). Type I is fatal in infancy, type II has a late infantile onset and is associated with survival into the second or third decade. Type III has its onset in childhood, and is slowly progressive. (J Med Genet 1996 Apr:33(4):281-3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Wadman, RI | 3 |
| van der Pol, WL | 2 |
| Bosboom, WM | 3 |
| Asselman, FL | 1 |
| van den Berg, LH | 4 |
| Iannaccone, ST | 4 |
| Vrancken, AF | 4 |
| Lunn, MR | 1 |
| Wang, CH | 1 |
| Bosboom, W | 1 |
| Wokke, JH | 3 |
| Merlini, L | 1 |
| Solari, A | 1 |
| Vita, G | 1 |
| Bertini, E | 1 |
| Minetti, C | 1 |
| Mongini, T | 1 |
| Mazzoni, E | 1 |
| Angelini, C | 1 |
| Morandi, L | 1 |
| Miller, RG | 1 |
| Moore, DH | 1 |
| Dronsky, V | 1 |
| Bradley, W | 1 |
| Barohn, R | 1 |
| Bryan, W | 1 |
| Prior, TW | 1 |
| Gelinas, DF | 1 |
| Iannaccone, S | 1 |
| Kissel, J | 1 |
| Leshner, R | 1 |
| Mendell, J | 1 |
| Mendoza, M | 1 |
| Russman, B | 1 |
| Samaha, F | 1 |
| Smith, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Respiratory Muscle Training in Patients With Spinal Muscular Atrophy (SMA).[NCT05632666] | 30 participants (Actual) | Interventional | 2021-02-02 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for gamma-aminobutyric acid and Spinal Muscular Atrophies of Childhood
| Article | Year |
|---|---|
Drug treatment for spinal muscular atrophy types II and III.
Topics: Adolescent; Amines; Child; Child, Preschool; Creatine; Cyclohexanecarboxylic Acids; gamma-Aminobutyr | 2020 |
Spinal muscular atrophy.
Topics: Action Potentials; Amines; Cyclic AMP Response Element-Binding Protein; Cyclohexanecarboxylic Acids; | 2008 |
Drug treatment for spinal muscular atrophy types II and III.
Topics: Amines; Creatine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Phenylbu | 2009 |
Drug treatment for spinal muscular atrophy types II and III.
Topics: Acetylcarnitine; Adolescent; Amines; Child; Child, Preschool; Creatine; Cyclohexanecarboxylic Acids; | 2011 |
Drug treatment for spinal muscular atrophy types II and III.
Topics: Acetylcarnitine; Adolescent; Amines; Child; Child, Preschool; Creatine; Cyclohexanecarboxylic Acids; | 2012 |
2 trials available for gamma-aminobutyric acid and Spinal Muscular Atrophies of Childhood
| Article | Year |
|---|---|
Role of gabapentin in spinal muscular atrophy: results of a multicenter, randomized Italian study.
Topics: Acetates; Adolescent; Adult; Amines; Arm; Child; Cyclohexanecarboxylic Acids; Female; Gabapentin; ga | 2003 |
A placebo-controlled trial of gabapentin in spinal muscular atrophy.
Topics: Acetates; Adult; Amines; Arm; Cyclohexanecarboxylic Acids; Double-Blind Method; Excitatory Amino Aci | 2001 |