gamma-aminobutyric acid has been researched along with Sleep Apnea, Obstructive in 10 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Despite its name, obstructive sleep apnea (OSA) is not caused by an airway obstruction that prevents breathing." | 3.01 | Sleep apnea pathophysiology. ( Andrisani, G, 2023) |
| "The consequences of insomnia, including issues with mood, behavior, and cognition, are discussed." | 2.53 | Pediatric Insomnia. ( Brown, KM; Malow, BA, 2016) |
| "The insular cortex is injured in obstructive sleep apnea (OSA) and responds inappropriately to autonomic challenges, suggesting neural reorganization." | 1.43 | Obstructive sleep apnea is associated with low GABA and high glutamate in the insular cortex. ( Aysola, R; Harper, RM; Macey, PM; Nagarajan, R; Sarma, MK; Siegel, JM; Thomas, MA, 2016) |
| "A total of 130 patients with OSAHS and 136 age- and gender-matched healthy controls were enrolled in this study." | 1.43 | Association between Single Nucleotide Polymorphisms in Gamma-Aminobutyric Acid B Receptor, Insulin Receptor Substrate-1, and Hypocretin Neuropeptide Precursor Genes and Susceptibility to Obstructive Sleep Apnea Hypopnea Syndrome in a Chinese Han Populatio ( Du, J; Li, Z; Qin, G; Tang, T; Wu, W; Zhou, X, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 8 (80.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrisani, G | 2 |
| Kakall, ZM | 1 |
| Pilowsky, PM | 1 |
| Farnham, MMJ | 1 |
| Leclere, JC | 1 |
| Marianowski, R | 1 |
| Monteyrol, PJ | 1 |
| Akkari, M | 1 |
| Chalumeau, F | 1 |
| Fayoux, P | 1 |
| Leboulanger, N | 1 |
| Franco, P | 1 |
| Couloigner, V | 1 |
| Mondain, M | 1 |
| Cillo, JE | 1 |
| Dattilo, DJ | 1 |
| Dergacheva, O | 1 |
| Brown, KM | 1 |
| Malow, BA | 1 |
| Macey, PM | 1 |
| Sarma, MK | 1 |
| Nagarajan, R | 1 |
| Aysola, R | 1 |
| Siegel, JM | 1 |
| Harper, RM | 1 |
| Thomas, MA | 1 |
| Li, Z | 1 |
| Tang, T | 1 |
| Du, J | 1 |
| Wu, W | 1 |
| Zhou, X | 1 |
| Qin, G | 1 |
| Horner, RL | 2 |
3 reviews available for gamma-aminobutyric acid and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Sleep apnea pathophysiology.
Topics: gamma-Aminobutyric Acid; Humans; Respiration; Sleep; Sleep Apnea Syndromes; Sleep Apnea, Obstructive | 2023 |
Pediatric Insomnia.
Topics: Actigraphy; Adolescent; Amines; Anti-Anxiety Agents; Autism Spectrum Disorder; Central Nervous Syste | 2016 |
The tongue and its control by sleep state-dependent modulators.
Topics: Airway Resistance; Animals; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Hypoglossal Ne | 2011 |
1 trial available for gamma-aminobutyric acid and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
Pre-emptive analgesia with pregabalin and celecoxib decreases postsurgical pain following maxillomandibular advancement surgery: a randomized controlled clinical trial.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Adult; Analgesia, Patient-Controlled; Analge | 2014 |
6 other studies available for gamma-aminobutyric acid and Sleep Apnea, Obstructive
| Article | Year |
|---|---|
PACAP-(6-38) or kynurenate microinjections in the RVLM prevent the development of sympathetic long-term facilitation after acute intermittent hypoxia.
Topics: Acute Disease; Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Glutamic Acid; Hypertension | 2018 |
Guidelines of the French Society of Otorhinolaryngology. Role of the ENT specialist in the diagnosis of obstructive sleep apnea-hypopnea syndrome (OSAHS) in children. Part 2: Diagnostic investigations apart from sleep studies.
Topics: Biomarkers; C-Reactive Protein; Child; Endoscopy; Epinephrine; France; gamma-Aminobutyric Acid; Huma | 2019 |
Chronic intermittent hypoxia alters neurotransmission from lateral paragigantocellular nucleus to parasympathetic cardiac neurons in the brain stem.
Topics: Animals; Brain Stem; Disease Models, Animal; Electric Stimulation; Female; gamma-Aminobutyric Acid; | 2015 |
Obstructive sleep apnea is associated with low GABA and high glutamate in the insular cortex.
Topics: Autonomic Nervous System; Case-Control Studies; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Gl | 2016 |
Association between Single Nucleotide Polymorphisms in Gamma-Aminobutyric Acid B Receptor, Insulin Receptor Substrate-1, and Hypocretin Neuropeptide Precursor Genes and Susceptibility to Obstructive Sleep Apnea Hypopnea Syndrome in a Chinese Han Populatio
Topics: Adult; Aged; Body Mass Index; Case-Control Studies; China; Female; gamma-Aminobutyric Acid; Gene Fre | 2016 |
Is there a rationale in modulating brainstem neurons in obstructive sleep apnea and is it clinically relevant?
Topics: Brain Stem; Cholinergic Fibers; gamma-Aminobutyric Acid; Glycine; Humans; Hypoglossal Nerve; Neurons | 2000 |