Page last updated: 2024-10-16

gamma-aminobutyric acid and Reperfusion Injury

gamma-aminobutyric acid has been researched along with Reperfusion Injury in 54 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"To investigate the effects of dexmedetomidine (DEX) on amino acid contents and the cerebral ultrastructure of rats with cerebral ischemia-reperfusion injury (I/R)."7.85Impact of dexmedetomidine on amino acid contents and the cerebral ultrastructure of rats with cerebral ischemia-reperfusion injury. ( Fu, Z; Lin, S; Shao, W; Zhou, G, 2017)
"Dexmedetomidine is capable of decreasing glutamergic content, and increasing GABAergic content, in order to decrease the injury of the cerebral ultrastructure, following cerebral ischemia-reperfusion injury."7.85Impact of dexmedetomidine on amino acid contents and the cerebral ultrastructure of rats with cerebral ischemia-reperfusion injury. ( Fu, Z; Lin, S; Shao, W; Zhou, G, 2017)
" This study aims to investigate the neuroprotective effects of gabapentin in an experimental spinal cord ischemia reperfusion injury."7.77Neuroprotective effects of gabapentin on spinal cord ischemia-reperfusion injury in rabbits. ( Börcek, AÖ; Doğulu, F; Durdağ, E; Emmez, H; Kale, A; Kılıç, N; Kurt, G; Lortlar, N; Yildirim, Z, 2011)
" Ouabain and monensin mimicked reperfusion injury and their toxicity was also reduced by taurine."7.69Protective effect of taurine against reperfusion injury in cultured rat astrocytes. ( Azuma, J; Baba, A; Kishida, Y; Matsuda, T; Takuma, K, 1996)
"Ouabain and monensin mimicked reperfusion injury and their toxicity was also reduced by taurine."5.29Protective effect of taurine against reperfusion injury in cultured rat astrocytes. ( Azuma, J; Baba, A; Kishida, Y; Matsuda, T; Takuma, K, 1996)
"To investigate the effects of dexmedetomidine (DEX) on amino acid contents and the cerebral ultrastructure of rats with cerebral ischemia-reperfusion injury (I/R)."3.85Impact of dexmedetomidine on amino acid contents and the cerebral ultrastructure of rats with cerebral ischemia-reperfusion injury. ( Fu, Z; Lin, S; Shao, W; Zhou, G, 2017)
"Dexmedetomidine is capable of decreasing glutamergic content, and increasing GABAergic content, in order to decrease the injury of the cerebral ultrastructure, following cerebral ischemia-reperfusion injury."3.85Impact of dexmedetomidine on amino acid contents and the cerebral ultrastructure of rats with cerebral ischemia-reperfusion injury. ( Fu, Z; Lin, S; Shao, W; Zhou, G, 2017)
" Although a number of studies have investigated that ginkgolide B, a purified terpene lactone component extracted from Ginkgo biloba leaves, is available "platelet activating factor (PAF) receptors antagonist", "antioxidant" with a variety of actions, very little has been performed to explore the effect of ginkgolide B on extracellular amino acids in experimental animal of focal cerebral ischemia/reperfusion."3.77Effect of ginkgolide B on striatal extracellular amino acids in middle cerebral artery occluded rats. ( Feng, W; Li, J; Li, SX; Wang, H; Yang, ZZ, 2011)
" This study aims to investigate the neuroprotective effects of gabapentin in an experimental spinal cord ischemia reperfusion injury."3.77Neuroprotective effects of gabapentin on spinal cord ischemia-reperfusion injury in rabbits. ( Börcek, AÖ; Doğulu, F; Durdağ, E; Emmez, H; Kale, A; Kılıç, N; Kurt, G; Lortlar, N; Yildirim, Z, 2011)
"Our latest study indicated that ethanol could attenuate cerebral ischemia/reperfusion-induced brain injury through activating Ionotropic glutamate receptors Kainate Family (Gluk1)-kainate (KA) receptors and gamma-aminobutyric acid (GABA) receptors."3.76Neuroprotection of ethanol against ischemia/reperfusion-induced brain injury through decreasing c-Jun N-terminal kinase 3 (JNK3) activation by enhancing GABA release. ( Gu, YH; Guan, QH; Hao, LY; Liu, Y; Qi, SH; Wang, M; Yan, H; Zhang, GY; Zhang, J, 2010)
" Therefore, it was aimed to study whether dipyridamole (CAS 58-32-2), an adenosine uptake inhibitor, or adenosine (CAS 58-61-7) could affect the rat brain gamma-aminobutyric acid (GABA, CAS 56-12-2) level after induction of cerebral ischemia, and to test their effect on the lactate dehydrogenase (LDH) activity of the ischemic rat brain."3.71Influence of inhibition of adenosine uptake on the gamma-aminobutyric acid level of the ischemic rat brain. ( Khattab, M; Seif-el-Nasr, M, 2002)
"The aim of this study was to determine wether flupirtine can slow down the changes seen in the rabbit retina after ischemia--reperfusion."3.69Protection of rabbit retina from ischemic injury by flupirtine. ( Osborne, NN; Pergande, G; Schwarz, M, 1996)
"Combined data show that flupirtine is a neuroprotective agent in retinal ischemia and that one mode of its mechanism of action is to influence ATP levels."3.69Protection of rabbit retina from ischemic injury by flupirtine. ( Osborne, NN; Pergande, G; Schwarz, M, 1996)
" Ouabain and monensin mimicked reperfusion injury and their toxicity was also reduced by taurine."3.69Protective effect of taurine against reperfusion injury in cultured rat astrocytes. ( Azuma, J; Baba, A; Kishida, Y; Matsuda, T; Takuma, K, 1996)
"Icaritin (ICT) has been previously demonstrated to display protective effects against cerebral ischemic reperfusion (I/R) by inhibiting oxidative stress, but the mechanism remains unclear."1.91UHPLC-ESI-QE-Orbitrap-MS based metabolomics reveals the antioxidant mechanism of icaritin on mice with cerebral ischemic reperfusion. ( Feng, Z; Liu, Z; Sun, C; Sun, L; Tang, Y; Yao, J; Zhang, G; Zhao, Y, 2023)
"TTC staining was used to detect cerebral infarction volume, and the brain water content of rats in each group was determined by wet and dry weight method."1.91[Effects of Governor Vessel electroacupuncture on chloridion homeostasis in the cortex of rats with limb spasm after cerebral ischemia-reperfusion]. ( Guo, J; Li, JW; Li, RQ; Mei, JJ; Wang, YY; Zhang, JY; Zhang, LH, 2023)
"This study utilized a cerebral ischemia reperfusion (IR) model to produce a stressful brain condition that highlights the possible involvement of a hippocampal GC/pERK1/2/BDNF pathway in the resulting sexual consequences of this ailment."1.72Insights into the role of pERK1/2 signaling in post-cerebral ischemia reperfusion sexual dysfunction in rats. ( El-Sahar, AE; Khattab, MA; Mohammed, RA; Saad, MA; Sayed, RH, 2022)
"Memantine was used as a positive control."1.43Low dose of L-glutamic acid attenuated the neurological dysfunctions and excitotoxicity in bilateral common carotid artery occluded mice. ( Abdul, KK; Justin, A; Ramanathan, M, 2016)
"Those that developed cerebral ischemia after MCAO were randomized to receive propylene glycol salt water and ligustrazine respectively."1.40Effect of ligustrazine on levels of amino acid neurotransmitters in rat striatum after cerebral ischemia-reperfusion injury. ( Bie, XD; Ge, LJ; Han, J; Wan, HT; Yang, JH; Zhang, YY, 2014)
"Mice exhibited spontaneous neuropathic pain behaviors, which were most obvious after ischemia for 5 h."1.38Patterns of nerve injury and neuropathic pain in ischemic neuropathy after ligation-reperfusion of femoral artery in mice. ( Chiang, HY; Hsieh, JH; Hsieh, ST; Lee, JE; Wang, KC, 2012)
" Compared with the model group, the concentration of Glu in the middle and large dosage groups of TGF, during the 120 min of ischemia, reduced by 38."1.32[Effects of tianma gouteng fang on transmitter amino acids in the hippocampus extracellular liquids in freely moving rats subjected to brain ischemia]. ( Du, GY; Sun, XF; Wang, DQ; Wang, W; Ye, ZG; Zhang, CY; Zhao, DZ, 2004)
"Lactic acidosis has been implicated; however, increases in the excitotoxic amino acid glutamate, which correlate with increased neuronal damage, may be the cause for the increased damage seen in hyperglycemic stroke."1.31The effect of streptozotocin-induced diabetes on the release of excitotoxic and other amino acids from the ischemic rat cerebral cortex. ( Diaz, FG; Guyot, LL; O'Regan, MH; Phillis, JW; Song, D, 2001)
"Dipyridamole was administered alone and in combination with adenosine and the effect of the drugs on the brain GABA level as well as on LDH activity was determined."1.31Influence of inhibition of adenosine uptake on the gamma-aminobutyric acid level of the ischemic rat brain. ( Khattab, M; Seif-el-Nasr, M, 2002)
"Flupirtine may lower the activity of NMDA receptors, thus causing ATP levels to be less affected in the presence of the drug as a secondary effect."1.29Protection of rabbit retina from ischemic injury by flupirtine. ( Osborne, NN; Pergande, G; Schwarz, M, 1996)
"When tiagabine was injected 10 min following onset of reperfusion, GABA levels remained elevated (200-470%) for 90 min."1.29Postischemic inhibition of GABA reuptake by tiagabine slows neuronal death in the gerbil hippocampus. ( Inglefield, JR; Perry, JM; Schwartz, RD, 1995)
" We used in vivo microdialysis to determine a suitable dosing regimen for tiagabine (NNC328) to elevate extracellular levels of GABA within the hippocampus."1.29Postischemic inhibition of GABA reuptake by tiagabine slows neuronal death in the gerbil hippocampus. ( Inglefield, JR; Perry, JM; Schwartz, RD, 1995)
"Ouabain and monensin mimicked reperfusion injury and their toxicity was also reduced by taurine."1.29Protective effect of taurine against reperfusion injury in cultured rat astrocytes. ( Azuma, J; Baba, A; Kishida, Y; Matsuda, T; Takuma, K, 1996)

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (22.22)18.2507
2000's17 (31.48)29.6817
2010's20 (37.04)24.3611
2020's5 (9.26)2.80

Authors

AuthorsStudies
Kumar, M1
Singh, G1
Kushwah, AS1
Surampalli, G1
Singh, TG1
Gupta, S1
Mohammed, RA1
Sayed, RH1
El-Sahar, AE1
Khattab, MA1
Saad, MA2
Du, Y2
Li, C1
Xu, S1
Yang, J1
Wan, H1
He, Y1
Tang, Y1
Sun, L1
Zhao, Y1
Yao, J1
Feng, Z1
Liu, Z1
Zhang, G1
Sun, C1
Wang, YY1
Li, RQ1
Li, JW1
Mei, JJ1
Zhang, LH1
Zhang, JY1
Guo, J1
Chen, C1
Zhou, X1
He, J1
Xie, Z1
Xia, S1
Lu, G1
Lin, S1
Zhou, G1
Shao, W1
Fu, Z1
Yang, CY1
Liu, SY1
Wang, HY1
Li, YL1
Guo, D1
Wang, XY1
Hua, W1
Wang, GL1
Zhang, M1
Sun, X1
Guo, F1
Gong, Y1
Xu, L1
Kubota, A1
Kobayashi, M1
Sarashina, S1
Takeno, R1
Yasuda, G1
Narumi, K1
Furugen, A1
Takahashi-Suzuki, N1
Iseki, K1
Han, J1
Wan, HT1
Yang, JH1
Zhang, YY1
Ge, LJ1
Bie, XD1
Kobuchi, S3
Tanaka, R3
Shintani, T3
Suzuki, R3
Tsutsui, H3
Ohkita, M3
Matsumura, Y3
Ayajiki, K3
Abdelsalam, RM1
Kenawy, SA1
Attia, AS1
Safonova, OA1
Popova, TN1
Slivkin, AI1
Talmi, Y1
Ramanathan, M2
Abdul, KK1
Justin, A2
Hirooka, K1
Miyamoto, O1
Itano, T1
Tokuda, M1
Shiraga, F1
Sugiura, T1
Fujii, T1
Qi, SH1
Liu, Y2
Hao, LY1
Guan, QH1
Gu, YH1
Zhang, J2
Yan, H1
Wang, M1
Zhang, GY2
Yang, ZZ1
Li, J1
Li, SX1
Feng, W1
Wang, H1
Kale, A1
Börcek, AÖ1
Emmez, H1
Yildirim, Z1
Durdağ, E1
Lortlar, N1
Kurt, G1
Doğulu, F1
Kılıç, N1
Ricci, L1
Valoti, M1
Sgaragli, G1
Frosini, M1
Lv, Q1
Han, D1
Xu, J1
Zong, YY1
Wang, Y2
Babu, CS1
Shanthakumari, S1
Zhu, SP1
Fei, SJ1
Zhang, JF1
Zhu, JZ1
Li, Y1
Liu, ZB1
Qiao, X1
Li, TT1
Lee, JE1
Wang, KC1
Chiang, HY1
Hsieh, JH1
Hsieh, ST1
Du, DS1
Zhu, T1
Ren, ST1
Xie, GL1
Li, SB1
Chu, DC1
Liu, XT1
Liu, M1
Ma, XB1
Zhou, MH1
Zhu, DN1
Deng, ZX1
Wang, J1
Fu, JH1
Du, GY2
Büyükuysal, RL1
Dijk, F2
van Leeuwen, S1
Kamphuis, W2
Zhang, CY1
Wang, W1
Ye, ZG1
Wang, DQ1
Sun, XF1
Zhao, DZ1
Dohmen, C1
Kumura, E1
Rosner, G1
Heiss, WD1
Graf, R1
Kang, TH1
Oh, HR1
Jung, SM1
Ryu, JH1
Park, MW1
Park, YK1
Kim, SY1
Epsztein, J1
Milh, M1
Bihi, RI1
Jorquera, I1
Ben-Ari, Y1
Represa, A1
Crépel, V1
Millecamps, M1
Coderre, TJ1
Neumann-Haefelin, T1
Hagemann, G1
Witte, OW1
Barnett, NL1
Osborne, NN2
Delbarre, B1
Delbarre, G1
Calinon, F1
Matsumoto, K1
Lo, EH1
Pierce, AR1
Halpern, EF1
Newcomb, R1
Schwarz, M1
Pergande, G1
Perlman, JI1
McCole, SM1
Pulluru, P1
Chang, CJ1
Lam, TT1
Tso, MO1
Yao, ZB1
Li, X1
Xu, ZC1
Tan, WK1
Williams, CE1
During, MJ1
Mallard, CE1
Gunning, MI1
Gunn, AJ1
Gluckman, PD1
Inglefield, JR1
Perry, JM1
Schwartz, RD1
Matsuda, T1
Takuma, K1
Kishida, Y1
Azuma, J1
Baba, A1
Zhang, Y2
Liu, GQ1
Liu, XD1
Xiao, XQ1
Heim, C1
Lan, J1
Sieklucka, M1
Kurz, T1
Riederer, P1
Gerlach, M1
Sontag, KH1
Guyot, LL3
Diaz, FG3
O'Regan, MH3
Song, D2
Phillis, JW3
Ren, J1
Xie, K1
Seif-el-Nasr, M1
Khattab, M1
Kang, TC1
Park, SK1
Hwang, IK1
An, SJ1
Choi, SY1
Cho, SW1
Won, MH1

Reviews

1 review available for gamma-aminobutyric acid and Reperfusion Injury

ArticleYear
The Roles of GABA in Ischemia-Reperfusion Injury in the Central Nervous System and Peripheral Organs.
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Central Nervous System; gamma-Aminobutyric Acid; Humans; Reperfusion Injury

2019

Other Studies

53 other studies available for gamma-aminobutyric acid and Reperfusion Injury

ArticleYear
Arbutin protects brain against middle cerebral artery occlusion-reperfusion (MCAo/R) injury.
    Biochemical and biophysical research communications, 2021, 11-05, Volume: 577

    Topics: Animals; Arbutin; Blood-Brain Barrier; Brain; Chromatography, High Pressure Liquid; Disease Models,

2021
Insights into the role of pERK1/2 signaling in post-cerebral ischemia reperfusion sexual dysfunction in rats.
    European journal of pharmacology, 2022, Oct-15, Volume: 933

    Topics: Animals; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cerebral Infarction; gamma-Aminobutyric

2022
LC-MS/MS combined with blood-brain dual channel microdialysis for simultaneous determination of active components of astragali radix-safflower combination and neurotransmitters in rats with cerebral ischemia reperfusion injury: Application in pharmacokine
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 106

    Topics: Animals; Aspartic Acid; Astragalus Plant; Blood-Brain Barrier; Carthamus tinctorius; Chalcone; Chrom

2022
UHPLC-ESI-QE-Orbitrap-MS based metabolomics reveals the antioxidant mechanism of icaritin on mice with cerebral ischemic reperfusion.
    PeerJ, 2023, Volume: 11

    Topics: Animals; Antioxidants; Arachidonic Acid; Chromatography, High Pressure Liquid; gamma-Aminobutyric Ac

2023
[Effects of Governor Vessel electroacupuncture on chloridion homeostasis in the cortex of rats with limb spasm after cerebral ischemia-reperfusion].
    Zhen ci yan jiu = Acupuncture research, 2023, Sep-25, Volume: 48, Issue:9

    Topics: Animals; Baclofen; Cerebral Cortex; Cerebral Infarction; Electroacupuncture; gamma-Aminobutyric Acid

2023
Impact of dexmedetomidine on amino acid contents and the cerebral ultrastructure of rats with cerebral ischemia-reperfusion injury.
    Acta cirurgica brasileira, 2017, Volume: 32, Issue:6

    Topics: Amino Acids; Animals; Brain Ischemia; Cerebral Cortex; Dexmedetomidine; gamma-Aminobutyric Acid; Glu

2017
Neuroprotection by Propofol Post-Conditioning: Focus on PKMζ/KCC2 Pathway Activity.
    Cellular and molecular neurobiology, 2018, Volume: 38, Issue:3

    Topics: Animals; gamma-Aminobutyric Acid; Hippocampus; Interneurons; K Cl- Cotransporters; Male; Neuroprotec

2018
[Ghrelin protects against hippocampal injury after global cerebral ischemia/reperfusion and regulate glutamic acid/γ-aminobutyric acid sensitive neuron discharge]
    Zhonghua wei zhong bing ji jiu yi xue, 2016, Volume: 28, Issue:5

    Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; gamma-Aminobutyric Acid; Ghrelin; Glutamic Acid

2016
Gamma-Aminobutyric Acid (GABA) Attenuates Ischemia Reperfusion-Induced Alterations in Intestinal Immunity.
    Biological & pharmaceutical bulletin, 2018, Volume: 41, Issue:12

    Topics: alpha-Defensins; Animals; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ileum; Immunity

2018
Effect of ligustrazine on levels of amino acid neurotransmitters in rat striatum after cerebral ischemia-reperfusion injury.
    Journal of Asian natural products research, 2014, Volume: 16, Issue:11

    Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Ischemia; Corpus Striatum; gamma-Aminobutyric Acid

2014
Mechanisms underlying the renoprotective effect of GABA against ischaemia/reperfusion-induced renal injury in rats.
    Clinical and experimental pharmacology & physiology, 2015, Volume: 42, Issue:3

    Topics: Acute Kidney Injury; Animals; Benzylamines; Bicuculline; Cytoprotection; GABA-A Receptor Antagonists

2015
Ischemic preconditioning and postconditioning alleviates hippocampal tissue damage through abrogation of apoptosis modulated by oxidative stress and inflammation during transient global cerebral ischemia-reperfusion in rats.
    Chemico-biological interactions, 2015, May-05, Volume: 232

    Topics: Animals; Apoptosis; Biomarkers; Brain Ischemia; Encephalitis; gamma-Aminobutyric Acid; Glutamic Acid

2015
Effects of a Preparation Containing Pantogam, Succinic Acid, and Chitosan on Activities of the Glutathione System and NADPH-Generating Enzymes in Rat Tissues under Conditions of Cerebral Ischemia/Reperfusion.
    Bulletin of experimental biology and medicine, 2015, Volume: 159, Issue:2

    Topics: Animals; Brain Ischemia; Chitosan; Drug Combinations; Free Radicals; gamma-Aminobutyric Acid; Glucos

2015
Low dose of L-glutamic acid attenuated the neurological dysfunctions and excitotoxicity in bilateral common carotid artery occluded mice.
    Behavioural pharmacology, 2016, Volume: 27, Issue:7

    Topics: Animals; Brain; Brain Ischemia; Carotid Artery, Common; Disease Models, Animal; Dose-Response Relati

2016
Both amacrine and bipolar cells release glutamate in the rat retina after ischemia/reperfusion insult in vitro.
    Current eye research, 2008, Volume: 33, Issue:9

    Topics: Amacrine Cells; Animals; Apoptosis; Calbindins; Female; gamma-Aminobutyric Acid; Glucose; Glutamic A

2008
Renoprotective effects of gamma-aminobutyric acid on ischemia/reperfusion-induced renal injury in rats.
    European journal of pharmacology, 2009, Nov-25, Volume: 623, Issue:1-3

    Topics: Animals; Baclofen; Benzylamines; GABA Agonists; GABA Antagonists; GABA-B Receptor Antagonists; gamma

2009
Neuroprotection of ethanol against ischemia/reperfusion-induced brain injury through decreasing c-Jun N-terminal kinase 3 (JNK3) activation by enhancing GABA release.
    Neuroscience, 2010, Jun-02, Volume: 167, Issue:4

    Topics: Animals; Apoptosis; Bicuculline; Brain Ischemia; CA1 Region, Hippocampal; Cadmium Chloride; Calcium

2010
Effect of ginkgolide B on striatal extracellular amino acids in middle cerebral artery occluded rats.
    Journal of ethnopharmacology, 2011, Jun-14, Volume: 136, Issue:1

    Topics: Amino Acids; Animals; Aspartic Acid; Brain Ischemia; Corpus Striatum; gamma-Aminobutyric Acid; Ginkg

2011
Neuroprotective effects of gabapentin on spinal cord ischemia-reperfusion injury in rabbits.
    Journal of neurosurgery. Spine, 2011, Volume: 15, Issue:3

    Topics: Amines; Animals; Caspase 3; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Gabapenti

2011
Mechanisms underlying the renoprotective effect of GABA against ischemia/reperfusion-induced renal injury in rats.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 338, Issue:3

    Topics: Acute Kidney Injury; Animals; Baclofen; Benzylamines; Bicuculline; Blood Urea Nitrogen; GABA Agonist

2011
Taurine-like GABA aminotransferase inhibitors prevent rabbit brain slices against oxygen-glucose deprivation-induced damage.
    Amino acids, 2012, Volume: 42, Issue:6

    Topics: 4-Aminobutyrate Transaminase; Animals; Brain; Brain Ischemia; gamma-Aminobutyric Acid; Glucose; Male

2012
Neuroprotection of GluK1 kainate receptor agonist ATPA against ischemic neuronal injury through inhibiting GluK2 kainate receptor-JNK3 pathway via GABA(A) receptors.
    Brain research, 2012, May-25, Volume: 1456

    Topics: Animals; Enzyme Activation; gamma-Aminobutyric Acid; GluK2 Kainate Receptor; Isoxazoles; Male; Mitog

2012
Elucidation of neuroprotective role of endogenous GABA and energy metabolites middle cerebral artery occluded model in rats.
    Indian journal of experimental biology, 2012, Volume: 50, Issue:6

    Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Brain; Disease Models, Animal; Excitatory Amino Acid

2012
Lateral hypothalamic area mediated the protective effects of microinjection of glutamate into interpositus nucleus on gastric ischemia-reperfusion injury in rats.
    Neuroscience letters, 2012, Sep-06, Volume: 525, Issue:1

    Topics: Animals; Apoptosis; Cell Proliferation; Cerebellum; gamma-Aminobutyric Acid; Gastric Juice; Gastric

2012
Patterns of nerve injury and neuropathic pain in ischemic neuropathy after ligation-reperfusion of femoral artery in mice.
    Journal of the peripheral nervous system : JPNS, 2012, Volume: 17, Issue:3

    Topics: Amines; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Femoral Artery; Gaba

2012
γ-Aminobutyric acid-mediated neurotransmission in cerebellar-hypothalamic circuit attenuates gastric mucosal injury induced by ischemia-reperfusion.
    Neurogastroenterology and motility, 2013, Volume: 25, Issue:4

    Topics: Animals; Celiac Artery; Cerebellum; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid;

2013
[Effect of tianma cuzhi keli (TMCZKL) on contents of transmitter amino acids of brain tissue in the mouse repetitious cerebral ischemia reperfusion].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2001, Volume: 26, Issue:1

    Topics: Animals; Aspartic Acid; Brain Ischemia; Cerebral Cortex; Drug Combinations; Drugs, Chinese Herbal; g

2001
Ischemia and reoxygenation induced amino acid release release and tissue damage in the slices of rat corpus striatum.
    Amino acids, 2004, Volume: 27, Issue:1

    Topics: Amino Acids; Animals; Aspartic Acid; Brain; Calcium; Citrulline; Corpus Striatum; Female; gamma-Amin

2004
Differential effects of ischemia/reperfusion on amacrine cell subtype-specific transcript levels in the rat retina.
    Brain research, 2004, Nov-12, Volume: 1026, Issue:2

    Topics: Amacrine Cells; Animals; Cluster Analysis; gamma-Aminobutyric Acid; Gene Expression Regulation; Glia

2004
An immunocytochemical study on specific amacrine cell subpopulations in the rat retina after ischemia.
    Brain research, 2004, Nov-12, Volume: 1026, Issue:2

    Topics: Amacrine Cells; Animals; Cell Count; Eye Diseases; gamma-Aminobutyric Acid; Gene Expression Regulati

2004
[Effects of tianma gouteng fang on transmitter amino acids in the hippocampus extracellular liquids in freely moving rats subjected to brain ischemia].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2004, Volume: 29, Issue:11

    Topics: Animals; Arginine; Brain Ischemia; Drug Combinations; Drugs, Chinese Herbal; Excitatory Amino Acids;

2004
Extracellular correlates of glutamate toxicity in short-term cerebral ischemia and reperfusion: a direct in vivo comparison between white and gray matter.
    Brain research, 2005, Mar-10, Volume: 1037, Issue:1-2

    Topics: Adenosine; Amino Acids; Animals; Brain; Brain Chemistry; Calcium; Cats; Cerebrovascular Circulation;

2005
Enhancement of neuroprotection of mulberry leaves (Morus alba L.) prepared by the anaerobic treatment against ischemic damage.
    Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:2

    Topics: Anaerobiosis; Animals; Brain Ischemia; Cell Hypoxia; Cell Survival; Cerebral Infarction; gamma-Amino

2006
Ongoing epileptiform activity in the post-ischemic hippocampus is associated with a permanent shift of the excitatory-inhibitory synaptic balance in CA3 pyramidal neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Jun-28, Volume: 26, Issue:26

    Topics: Animals; Electroencephalography; Electrophysiology; Epilepsy; gamma-Aminobutyric Acid; Glutamic Acid

2006
Rats with chronic post-ischemia pain exhibit an analgesic sensitivity profile similar to human patients with complex regional pain syndrome--type I.
    European journal of pharmacology, 2008, Mar-31, Volume: 583, Issue:1

    Topics: Amitriptyline; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dos

2008
Cellular correlates of neuronal hyperexcitability in the vicinity of photochemically induced cortical infarcts in rats in vitro.
    Neuroscience letters, 1995, Jun-30, Volume: 193, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Cerebral Infarction; Electrophysiology; gamma

1995
Redistribution of GABA immunoreactivity following central retinal artery occlusion.
    Brain research, 1995, Apr-24, Volume: 677, Issue:2

    Topics: Animals; Electroretinography; Eye; gamma-Aminobutyric Acid; Immunohistochemistry; Rats; Rats, Wistar

1995
Action of trimetazidine on retina of gerbils after ischemia reperfusion insult: determination of .OH, amino acids, and electroretinogram.
    Annals of the New York Academy of Sciences, 1994, Nov-17, Volume: 738

    Topics: Amino Acids; Animals; Aspartic Acid; Electroretinography; Female; gamma-Aminobutyric Acid; Gentisate

1994
Secondary elevation of extracellular neurotransmitter amino acids in the reperfusion phase following focal cerebral ischemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1996, Volume: 16, Issue:1

    Topics: Amino Acids; Analysis of Variance; Animals; Aspartic Acid; Basal Ganglia; Cerebral Cortex; Cerebrosp

1996
Protection of rabbit retina from ischemic injury by flupirtine.
    Investigative ophthalmology & visual science, 1996, Volume: 37, Issue:2

    Topics: Adenosine Triphosphate; Aminopyridines; Analgesics; Animals; Electroretinography; gamma-Aminobutyric

1996
Disturbances in the distribution of neurotransmitters in the rat retina after ischemia.
    Current eye research, 1996, Volume: 15, Issue:6

    Topics: Animals; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Intraocular Pressure; Ischemi

1996
GABAergic and asymmetrical synapses on somata of GABAergic neurons in CA1 and CA3 regions of rat hippocampus. A quantitative electron microscopic analysis.
    Stroke, 1996, Volume: 27, Issue:8

    Topics: Animals; gamma-Aminobutyric Acid; Hippocampus; Immunohistochemistry; Male; Microscopy, Immunoelectro

1996
Accumulation of cytotoxins during the development of seizures and edema after hypoxic-ischemic injury in late gestation fetal sheep.
    Pediatric research, 1996, Volume: 39, Issue:5

    Topics: Animals; Aspartic Acid; Brain Edema; Brain Ischemia; Cytotoxins; Electroencephalography; Extracellul

1996
Postischemic inhibition of GABA reuptake by tiagabine slows neuronal death in the gerbil hippocampus.
    Hippocampus, 1995, Volume: 5, Issue:5

    Topics: Animals; Cell Death; gamma-Aminobutyric Acid; Gerbillinae; Hippocampus; Hypothermia; Male; Microdial

1995
Protective effect of taurine against reperfusion injury in cultured rat astrocytes.
    Advances in experimental medicine and biology, 1996, Volume: 403

    Topics: Animals; Animals, Newborn; Astrocytes; beta-Alanine; Calcium; Cell Survival; Cells, Cultured; Cerebr

1996
Efflux transport of [3H]GABA across blood-brain barrier after cerebral ischemia-reperfusion in rats.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1999, Volume: 20, Issue:3

    Topics: Animals; Blood-Brain Barrier; Brain Ischemia; gamma-Aminobutyric Acid; Male; Microinjections; Proben

1999
Cerebral oligaemia episode triggers free radical formation and late cognitive deficiencies.
    The European journal of neuroscience, 2000, Volume: 12, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Carotid Stenosis; Cognition Disorders; Corpu

2000
Topical glucose and accumulation of excitotoxic and other amino acids in ischemic cerebral cortex.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2000, Volume: 32, Issue:1

    Topics: Animals; Aspartic Acid; Blood Pressure; Brain Ischemia; Carbon Dioxide; Cerebral Cortex; Ethanolamin

2000
The effect of intravenous insulin on accumulation of excitotoxic and other amino acids in the ischemic rat cerebral cortex.
    Neuroscience letters, 2000, Jul-07, Volume: 288, Issue:1

    Topics: Animals; Aspartic Acid; Brain Chemistry; Cerebral Cortex; Energy Metabolism; gamma-Aminobutyric Acid

2000
The effect of streptozotocin-induced diabetes on the release of excitotoxic and other amino acids from the ischemic rat cerebral cortex.
    Neurosurgery, 2001, Volume: 48, Issue:2

    Topics: Acute Disease; Amino Acids; Animals; Blood Glucose; Brain Ischemia; Cerebral Cortex; Chronic Disease

2001
[Effect of guizhi fuling pills on the changes of Ca2+ and amino acids in rats with cerebral ischemia and reperfusion].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1998, Volume: 23, Issue:9

    Topics: Animals; Brain; Brain Ischemia; Calcium; Drug Combinations; Drugs, Chinese Herbal; Female; gamma-Ami

1998
Influence of inhibition of adenosine uptake on the gamma-aminobutyric acid level of the ischemic rat brain.
    Arzneimittel-Forschung, 2002, Volume: 52, Issue:5

    Topics: Adenosine; Animals; Biomarkers; Brain; Brain Chemistry; Brain Ischemia; Cerebral Cortex; Dipyridamol

2002
Spatial and temporal alterations in the GABA shunt in the gerbil hippocampus following transient ischemia.
    Brain research, 2002, Jul-19, Volume: 944, Issue:1-2

    Topics: Aldehyde Oxidoreductases; Animals; Brain Ischemia; Carrier Proteins; GABA Plasma Membrane Transport

2002