gamma-aminobutyric acid has been researched along with Psychomotor Agitation in 19 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Psychomotor Agitation: A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twelve patients with moderate to severe dementia and severe behavioral disorders were treated with open-label gabapentin (200-1,200 mg/day) for 8 weeks in a prospective case-series design." | 9.09 | Effectiveness of gabapentin for the treatment of behavioral disorders in dementia. ( Herrmann, N; Lanctôt, K; Myszak, M, 2000) |
| "Our patient, a 77-year-old Czech woman with incipient vascular dementia, received gabapentin 400mg at bedtime for 6 months and showed convincing improvement." | 7.77 | Gabapentin in the treatment of dementia-associated nocturnal agitation. ( Busek, P; Buskova, J; Nevsimalova, S, 2011) |
| "Gabapentin was generally well tolerated in this population." | 6.69 | Effectiveness of gabapentin for the treatment of behavioral disorders in dementia. ( Herrmann, N; Lanctôt, K; Myszak, M, 2000) |
| "Gabapentin was very effective in treating nocturnal agitation." | 5.37 | Gabapentin in the treatment of dementia-associated nocturnal agitation. ( Busek, P; Buskova, J; Nevsimalova, S, 2011) |
| " According to a predefined scheme for 8 weeks, all patients in the intervention group received individual daily pain treatment with acetaminophen, extended release morphine, buprenorphine transdermal patch, and/or pregabaline." | 5.19 | The response of agitated behavior to pain management in persons with dementia. ( Aarsland, D; Ballard, C; Cohen-Mansfield, J; Husebo, BS; Seifert, R, 2014) |
| "Twelve patients with moderate to severe dementia and severe behavioral disorders were treated with open-label gabapentin (200-1,200 mg/day) for 8 weeks in a prospective case-series design." | 5.09 | Effectiveness of gabapentin for the treatment of behavioral disorders in dementia. ( Herrmann, N; Lanctôt, K; Myszak, M, 2000) |
| " The purpose of this review of the literature is to assess the interest and the limits of anticonvulsant mood stabilizers (carbamazepine, valproic acid, gabapentin, lamotrigine, topiramate, oxcarbazepine) in the treatment of the so-called "noncognitive" symptoms of dementia." | 4.84 | [Anticonvulsant mood stabilizers in the treatment of behavioral and psychological symptoms of dementia (BPSD)]. ( Pinheiro, D, 2008) |
| "Among these medications, only carbamazepine demonstrated its efficacy in behavioral and psychological symptoms of dementia (BPSD) in controlled studies, notably that of Tariot et al." | 4.84 | [Anticonvulsant mood stabilizers in the treatment of behavioral and psychological symptoms of dementia (BPSD)]. ( Pinheiro, D, 2008) |
| "Our patient, a 77-year-old Czech woman with incipient vascular dementia, received gabapentin 400mg at bedtime for 6 months and showed convincing improvement." | 3.77 | Gabapentin in the treatment of dementia-associated nocturnal agitation. ( Busek, P; Buskova, J; Nevsimalova, S, 2011) |
| "A 54-year-old woman was undergoing chemotherapy with gemcitabine and oxaliplatin (GEMOX) for stage II-B pancreatic adenocarcinoma." | 3.74 | Successful amelioration of oxaliplatin-induced hyperexcitability syndrome with the antiepileptic pregabalin in a patient with pancreatic cancer. ( Hashmi, S; Saif, MW, 2008) |
| "In addition, restlessness and pacing were sensible to analgesics." | 2.79 | The response of agitated behavior to pain management in persons with dementia. ( Aarsland, D; Ballard, C; Cohen-Mansfield, J; Husebo, BS; Seifert, R, 2014) |
| "Gabapentin was generally well tolerated in this population." | 2.69 | Effectiveness of gabapentin for the treatment of behavioral disorders in dementia. ( Herrmann, N; Lanctôt, K; Myszak, M, 2000) |
| "The 6-Hz-induced seizures were accompanied by reduced brain 5-HT, DA, NE, histamine, GABA, and enhanced glutamate levels." | 1.46 | Parachlorophenylalanine-induced 5-HT depletion alters behavioral and brain neurotransmitters levels in 6-Hz psychomotor seizure model in mice. ( Jahan, K; Pillai, KK; Vohora, D, 2017) |
| "Hemichorea-hemiballism (HC-HB) in uncontrolled diabetes mellitus is an uncommon manifestation of hyperglycemia." | 1.42 | Increased intracortical inhibition in hyperglycemic hemichorea-hemiballism. ( Chen, R; Li, JY, 2015) |
| "Gabapentin was very effective in treating nocturnal agitation." | 1.37 | Gabapentin in the treatment of dementia-associated nocturnal agitation. ( Busek, P; Buskova, J; Nevsimalova, S, 2011) |
| " In addition to reassurance, pregabalin was prescribed for these myotonic symptoms at a dosage of 50 mg by mouth three times daily." | 1.35 | Successful amelioration of oxaliplatin-induced hyperexcitability syndrome with the antiepileptic pregabalin in a patient with pancreatic cancer. ( Hashmi, S; Saif, MW, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.53) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 7 (36.84) | 29.6817 |
| 2010's | 6 (31.58) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Husebo, BS | 1 |
| Ballard, C | 1 |
| Cohen-Mansfield, J | 1 |
| Seifert, R | 1 |
| Aarsland, D | 1 |
| Li, JY | 1 |
| Chen, R | 1 |
| Stratton, MS | 1 |
| Staros, M | 1 |
| Budefeld, T | 1 |
| Searcy, BT | 1 |
| Nash, C | 1 |
| Eitel, C | 1 |
| Carbone, D | 1 |
| Handa, RJ | 1 |
| Majdic, G | 1 |
| Tobet, SA | 1 |
| Jahan, K | 1 |
| Pillai, KK | 1 |
| Vohora, D | 1 |
| Pinheiro, D | 1 |
| Buskova, J | 1 |
| Busek, P | 1 |
| Nevsimalova, S | 1 |
| Galic, MA | 1 |
| Riazi, K | 1 |
| Pittman, QJ | 1 |
| TAKAHASHI, H | 1 |
| Saif, MW | 1 |
| Hashmi, S | 1 |
| Lin, JJ | 1 |
| Chang, MK | 1 |
| Regan, WM | 1 |
| Gordon, SM | 1 |
| Goldenberg, G | 1 |
| Kahaner, K | 1 |
| Basavaraju, N | 1 |
| Rangu, S | 1 |
| Low, RA | 1 |
| Brandes, M | 1 |
| Herrmann, N | 1 |
| Lanctôt, K | 1 |
| Myszak, M | 1 |
| Roane, DM | 1 |
| Feinberg, TE | 1 |
| Meckler, L | 1 |
| Miner, CR | 1 |
| Scicutella, A | 1 |
| Rosenthal, RN | 1 |
| Lindenmayer, JP | 1 |
| Bozikas, V | 1 |
| Bascialla, F | 1 |
| Yulis, P | 1 |
| Savvidou, I | 1 |
| Karavatos, A | 1 |
| Megna, JL | 1 |
| Devitt, PJ | 1 |
| Sauro, MD | 1 |
| Dewan, MJ | 1 |
| Dereux-Mortier, SA | 1 |
| Dereux, JF | 1 |
| Gallois, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Impact of Pain on Behavioural Disturbances in Patients With Moderate and Severe Dementia. A Cluster Randomized Trial[NCT01021696] | Phase 2/Phase 3 | 352 participants (Actual) | Interventional | 2009-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for gamma-aminobutyric acid and Psychomotor Agitation
| Article | Year |
|---|---|
[Anticonvulsant mood stabilizers in the treatment of behavioral and psychological symptoms of dementia (BPSD)].
Topics: Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dementia; Fructose; Gabap | 2008 |
Cytokines and brain excitability.
Topics: Akathisia, Drug-Induced; Animals; Brain; Cytokines; Down-Regulation; Epilepsy; gamma-Aminobutyric Ac | 2012 |
Hemiballism-hemichorea and non-ketotic hyperglycaemia.
Topics: Aged; Basal Ganglia Diseases; Chorea; Dementia, Multi-Infarct; Diabetes Complications; Female; gamma | 1994 |
The pathophysiology of agitation.
Topics: Aggression; Behavioral Symptoms; Bipolar Disorder; Dementia; Dopamine; gamma-Aminobutyric Acid; Huma | 2000 |
3 trials available for gamma-aminobutyric acid and Psychomotor Agitation
| Article | Year |
|---|---|
The response of agitated behavior to pain management in persons with dementia.
Topics: Acetaminophen; Aged, 80 and over; Analgesics; Buprenorphine; Delayed-Action Preparations; Dementia; | 2014 |
Effectiveness of gabapentin for the treatment of behavioral disorders in dementia.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Anti-Anxiety Agents; Behavioral Symptoms; Cyclohexanecarb | 2000 |
Gabapentin's effect on agitation in severely and persistently mentally ill patients.
Topics: Acetates; Amines; Antimanic Agents; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobuty | 2002 |
12 other studies available for gamma-aminobutyric acid and Psychomotor Agitation
| Article | Year |
|---|---|
Increased intracortical inhibition in hyperglycemic hemichorea-hemiballism.
Topics: Aged; Aged, 80 and over; Chorea; Dyskinesias; Evoked Potentials, Motor; Female; gamma-Aminobutyric A | 2015 |
Embryonic GABA(B) receptor blockade alters cell migration, adult hypothalamic structure, and anxiety- and depression-like behaviors sex specifically in mice.
Topics: Animals; Anxiety; Baclofen; Cell Movement; Depression; Embryo, Mammalian; Female; GABA-B Receptor An | 2014 |
Parachlorophenylalanine-induced 5-HT depletion alters behavioral and brain neurotransmitters levels in 6-Hz psychomotor seizure model in mice.
Topics: Animals; Brain; Disease Models, Animal; Electroshock; gamma-Aminobutyric Acid; Glutamine; Male; Mice | 2017 |
Gabapentin in the treatment of dementia-associated nocturnal agitation.
Topics: Aged; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Darkness; Dementia; Female; Gabapent | 2011 |
[Regulation of nerve cell excitability and gamma-aminobutyric acid].
Topics: Amino Acids; Antifibrinolytic Agents; gamma-Aminobutyric Acid; Nervous System Physiological Phenomen | 1962 |
Successful amelioration of oxaliplatin-induced hyperexcitability syndrome with the antiepileptic pregabalin in a patient with pancreatic cancer.
Topics: Adenocarcinoma; Adult; Anticonvulsants; Antimetabolites, Antineoplastic; Antineoplastic Agents; Calc | 2008 |
Gabapentin for behavioral agitation in Alzheimer's disease.
Topics: Acetates; Aged; Alzheimer Disease; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Admini | 1997 |
Gabapentin for disruptive behaviour in an elderly demented patient.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Dementia; D | 1998 |
Gabapentin for the management of agitation.
Topics: Acetates; Aggression; Amines; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobut | 1999 |
Treatment of dementia-associated agitation with gabapentin.
Topics: Acetates; Aged; Aged, 80 and over; Alzheimer Disease; Amines; Anticonvulsants; Cyclohexanecarboxylic | 2000 |
Gabapentin for behavioral dyscontrol with mental retardation.
Topics: Acetates; Adult; Amines; Anticonvulsants; Antipsychotic Agents; Cyclohexanecarboxylic Acids; Drug Th | 2001 |
[Hemiballism caused by metastasis to Luys' body].
Topics: Adenocarcinoma; Aged; Basal Ganglia Diseases; Brain Neoplasms; Diencephalon; gamma-Aminobutyric Acid | 1985 |