gamma-aminobutyric acid has been researched along with Porphyrias in 8 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Symptoms of acute porphyria have been attributed to effects of delta-aminolevulinic acid (ALA)." | 7.65 | delta-Aminolevulinic acid: influences on synaptic GABA receptor binding may explain CNS symptoms of porphyria. ( Müller, WE; Snyder, SH, 1977) |
| "Symptoms of acute porphyria have been attributed to effects of delta-aminolevulinic acid (ALA)." | 5.26 | delta-Aminolevulinic acid: influences on synaptic GABA receptor binding may explain CNS symptoms of porphyria. ( Müller, WE; Snyder, SH, 1977) |
| "Symptoms of acute porphyria have been attributed to effects of delta-aminolevulinic acid (ALA)." | 3.65 | delta-Aminolevulinic acid: influences on synaptic GABA receptor binding may explain CNS symptoms of porphyria. ( Müller, WE; Snyder, SH, 1977) |
| " However, results obtained with dispersed cells in culture may not necessarily reflect the situation in vivo where the cell may have a far greater resistance to the effects of toxic agents." | 1.26 | delta-Aminolaevulinic acid uptake, toxicity, and effect on [14C]gamma-aminobutyric acid uptake into neurons and glia in culture. ( Lamm, MC; Percy, VA; Taljaard, JJ, 1981) |
| "Symptoms of acute porphyria have been attributed to effects of delta-aminolevulinic acid (ALA)." | 1.26 | delta-Aminolevulinic acid: influences on synaptic GABA receptor binding may explain CNS symptoms of porphyria. ( Müller, WE; Snyder, SH, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meldrum, B | 1 |
| Silbergeld, EK | 2 |
| Bonkowsky, HL | 1 |
| Schady, W | 1 |
| Hruska, RE | 1 |
| Bradley, D | 1 |
| Lamon, JM | 1 |
| Frykholm, BC | 1 |
| Percy, VA | 1 |
| Lamm, MC | 1 |
| Taljaard, JJ | 1 |
| Reynolds, NC | 1 |
| Müller, WE | 1 |
| Snyder, SH | 1 |
| Brennan, MJ | 1 |
| Cantrill, RC | 1 |
2 reviews available for gamma-aminobutyric acid and Porphyrias
| Article | Year |
|---|---|
GABA and acute psychoses.
Topics: Acute Disease; Animals; Brain; Cats; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Limbi | 1982 |
Neurologic manifestations of acute porphyria.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Central Nervous System; Depression; Electrophysiology; | 1982 |
6 other studies available for gamma-aminobutyric acid and Porphyrias
| Article | Year |
|---|---|
Indirectly acting neurotoxins.
Topics: Aminolevulinic Acid; Animals; Brain; Dopamine; Estradiol; Female; gamma-Aminobutyric Acid; Lead Pois | 1983 |
Neurotoxic aspects of porphyrinopathies: lead and succinylacetone.
Topics: 5-Aminolevulinate Synthetase; Animals; Brain; gamma-Aminobutyric Acid; Heme; Heptanoates; Heptanoic | 1982 |
delta-Aminolaevulinic acid uptake, toxicity, and effect on [14C]gamma-aminobutyric acid uptake into neurons and glia in culture.
Topics: Aminolevulinic Acid; Animals; Brain; Cells, Cultured; Chick Embryo; Dinitrophenols; gamma-Aminobutyr | 1981 |
Epilepsy in porphyria.
Topics: 5-Aminolevulinate Synthetase; Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; | 1996 |
delta-Aminolevulinic acid: influences on synaptic GABA receptor binding may explain CNS symptoms of porphyria.
Topics: Aminolevulinic Acid; Animals; Anura; Binding, Competitive; Brain; Dose-Response Relationship, Drug; | 1977 |
Delta-aminolaevulinic acid is a potent agonist for GABA autoreceptors.
Topics: Aminolevulinic Acid; Animals; Bicuculline; gamma-Aminobutyric Acid; Levulinic Acids; Male; Picrotoxi | 1979 |