gamma-aminobutyric acid has been researched along with Porphyria, Acute Intermittent in 8 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Porphyria, Acute Intermittent: An autosomal dominant porphyria that is due to a deficiency of HYDROXYMETHYLBILANE SYNTHASE in the LIVER, the third enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features are recurrent and life-threatening neurologic disturbances, ABDOMINAL PAIN, and elevated level of AMINOLEVULINIC ACID and PORPHOBILINOGEN in the urine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Gabapentin is a new antiepileptic drug not appreciably metabolized by the liver in humans, and it appears to be safe and effective in the maintenance therapy of epilepsy in these patients." | 3.70 | Treatment of seizures in acute intermittent porphyria: safety and efficacy of gabapentin. ( Brambilla, A; Erli, LC; Grandi, R; Mirabile, D; Zadra, M, 1998) |
| "Gabapentin was prescribed for the control of seizure and pain before the diagnosis of acute intermittent porphyria was confirmed." | 1.36 | Gabapentin reduces neurovisceral pain of porphyria. ( Chen, JT; Liao, KK; Lin, CY; Lin, YY; Niu, DM; Tsao, YC, 2010) |
| "The patient was initially treated for her abdominal pain and vomiting." | 1.35 | Drug use in porphyria: a therapeutic dilemma. ( Jimmy, B; Jose, J; Saravu, K; Shastry, BA, 2008) |
| "Gabapentin is a new antiepileptic drug not appreciably metabolized by the liver in humans, and it appears to be safe and effective in the maintenance therapy of epilepsy in these patients." | 1.30 | Treatment of seizures in acute intermittent porphyria: safety and efficacy of gabapentin. ( Brambilla, A; Erli, LC; Grandi, R; Mirabile, D; Zadra, M, 1998) |
| " Gabapentin is a new antiepileptic drug not appreciably metabolized by the liver in humans, and it appears to be safe and effective in the maintenance therapy of epilepsy in these patients." | 1.30 | Treatment of seizures in acute intermittent porphyria: safety and efficacy of gabapentin. ( Brambilla, A; Erli, LC; Grandi, R; Mirabile, D; Zadra, M, 1998) |
| "Gabapentin is a new AED not appreciably metabolized by the liver in humans." | 1.29 | Gabapentin treatment of seizures in acute intermittent porphyria. ( Tatum, WO; Zachariah, SB, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, TC | 1 |
| Lai, SL | 1 |
| Hsu, SP | 1 |
| Ro, LS | 1 |
| Jose, J | 1 |
| Saravu, K | 1 |
| Shastry, BA | 1 |
| Jimmy, B | 1 |
| Tsao, YC | 1 |
| Niu, DM | 1 |
| Chen, JT | 1 |
| Lin, CY | 1 |
| Lin, YY | 1 |
| Liao, KK | 1 |
| Bhatia, R | 1 |
| Vibha, D | 1 |
| Srivastava, MV | 1 |
| Prasad, K | 1 |
| Tripathi, M | 1 |
| Bhushan Singh, M | 1 |
| Tatum, WO | 1 |
| Zachariah, SB | 1 |
| Puy, H | 1 |
| Deybach, JC | 1 |
| Bogdan, A | 1 |
| Callebert, J | 1 |
| Baumgartner, M | 1 |
| Voisin, P | 1 |
| Nordmann, Y | 1 |
| Touitou, Y | 1 |
| Zadra, M | 1 |
| Grandi, R | 1 |
| Erli, LC | 1 |
| Mirabile, D | 1 |
| Brambilla, A | 1 |
| Arora, A | 1 |
| Mahajan, V | 1 |
8 other studies available for gamma-aminobutyric acid and Porphyria, Acute Intermittent
| Article | Year |
|---|---|
Treatment of neuropathic pain in acute intermittent porphyria with gabapentin.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; | 2013 |
Drug use in porphyria: a therapeutic dilemma.
Topics: Abdominal Pain; Adult; Amines; Anticonvulsants; Antiemetics; Antihypertensive Agents; Chest Pain; Cy | 2008 |
Gabapentin reduces neurovisceral pain of porphyria.
Topics: Abdomen, Acute; Amines; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; | 2010 |
Use of propofol anesthesia and adjunctive treatment with levetiracetam and gabapentin in managing status epilepticus in a patient of acute intermittent porphyria.
Topics: Amines; Anesthetics, Intravenous; Anticonvulsants; Child; Comorbidity; Cyclohexanecarboxylic Acids; | 2008 |
Gabapentin treatment of seizures in acute intermittent porphyria.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-A | 1995 |
Increased delta aminolevulinic acid and decreased pineal melatonin production. A common event in acute porphyria studies in the rat.
Topics: Acetylserotonin O-Methyltransferase; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Aminolevul | 1996 |
Treatment of seizures in acute intermittent porphyria: safety and efficacy of gabapentin.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; | 1998 |
Gabapentin in seizures due to acute intermittent porphyria.
Topics: Acetates; Adult; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Ami | 2000 |