gamma-aminobutyric acid has been researched along with Polycystic Ovary Syndrome in 11 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Polycystic Ovary Syndrome: A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The study was undertaken to investigate the possible protective and ameliorating effects of GABA in Letrozole induced PCOS model in rats by targeting insulin resistance." | 7.85 | Protective effects of GABA against metabolic and reproductive disturbances in letrozole induced polycystic ovarian syndrome in rats. ( Afsar, T; Almajwal, A; Jahan, S; Pirzada, M; Rauf, N; Razak, S; Ullah, A; Ullah, H, 2017) |
| " The study was undertaken to investigate the possible protective and ameliorating effects of GABA in Letrozole induced PCOS model in rats by targeting insulin resistance." | 3.85 | Protective effects of GABA against metabolic and reproductive disturbances in letrozole induced polycystic ovarian syndrome in rats. ( Afsar, T; Almajwal, A; Jahan, S; Pirzada, M; Rauf, N; Razak, S; Ullah, A; Ullah, H, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 4 (36.36) | 2.80 |
| Authors | Studies |
|---|---|
| Szeliga, A | 1 |
| Rudnicka, E | 1 |
| Maciejewska-Jeske, M | 1 |
| Kucharski, M | 1 |
| Kostrzak, A | 1 |
| Hajbos, M | 1 |
| Niwczyk, O | 1 |
| Smolarczyk, R | 1 |
| Meczekalski, B | 1 |
| Silva, MSB | 2 |
| Campbell, RE | 2 |
| Eepho, OI | 1 |
| Bashir, AM | 1 |
| Oniyide, AA | 1 |
| Aturamu, A | 1 |
| Owolabi, OV | 1 |
| Ajadi, IO | 1 |
| Fafure, AA | 1 |
| Ajadi, MB | 1 |
| Areloegbe, SE | 1 |
| Olaniyi, KS | 1 |
| Liang, Z | 1 |
| Di, N | 1 |
| Li, L | 1 |
| Yang, D | 1 |
| Kawwass, JF | 1 |
| Sanders, KM | 1 |
| Loucks, TL | 1 |
| Rohan, LC | 1 |
| Berga, SL | 1 |
| Holmberg, E | 1 |
| Sjöstedt, J | 1 |
| Malinina, E | 1 |
| Johansson, M | 1 |
| Turkmen, S | 1 |
| Ragagnin, G | 1 |
| Lundqvist, A | 1 |
| Löfgren, M | 1 |
| Jaukkuri, L | 1 |
| Bixo, M | 1 |
| Bäckström, T | 1 |
| Ullah, A | 1 |
| Jahan, S | 1 |
| Razak, S | 1 |
| Pirzada, M | 1 |
| Ullah, H | 1 |
| Almajwal, A | 1 |
| Rauf, N | 1 |
| Afsar, T | 1 |
| Chaudhari, N | 1 |
| Dawalbhakta, M | 1 |
| Nampoothiri, L | 1 |
| Desroziers, E | 1 |
| Hessler, S | 1 |
| Prescott, M | 1 |
| Coyle, C | 1 |
| Herbison, AE | 1 |
| Chaudhari, NK | 1 |
| Nampoothiri, LP | 1 |
| Sullivan, SD | 1 |
| Moenter, SM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pathogenesis of Functional Hypothalamic Amenorrhea[NCT01674426] | 17 participants (Actual) | Interventional | 1997-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for gamma-aminobutyric acid and Polycystic Ovary Syndrome
| Article | Year |
|---|---|
Neuroendocrine Determinants of Polycystic Ovary Syndrome.
Topics: Acetylcholine; Dopamine; Female; Galanin; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Relea | 2022 |
Allopregnanolone involvement in feeding regulation, overeating and obesity.
Topics: Animals; Female; gamma-Aminobutyric Acid; Humans; Hyperphagia; Obesity; Polycystic Ovary Syndrome; P | 2018 |
9 other studies available for gamma-aminobutyric acid and Polycystic Ovary Syndrome
| Article | Year |
|---|---|
Polycystic Ovary Syndrome and the Neuroendocrine Consequences of Androgen Excess.
Topics: Adult; Androgens; Animals; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Humans; | 2022 |
Modulation of GABA by sodium butyrate ameliorates hypothalamic inflammation in experimental model of PCOS.
Topics: Animals; Butyric Acid; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Humans; Letrozole; M | 2023 |
Gut microbiota alterations reveal potential gut-brain axis changes in polycystic ovary syndrome.
Topics: Adult; Bacteria; Brain-Gut Axis; Dysbiosis; Feces; Female; Follicle Stimulating Hormone; gamma-Amino | 2021 |
Increased cerebrospinal fluid levels of GABA, testosterone and estradiol in women with polycystic ovary syndrome.
Topics: Adult; Androstenedione; Cross-Sectional Studies; Estradiol; Female; gamma-Aminobutyric Acid; Glucose | 2017 |
Protective effects of GABA against metabolic and reproductive disturbances in letrozole induced polycystic ovarian syndrome in rats.
Topics: Androgen Antagonists; Animals; Blood Glucose; Body Weight; Catalase; Estradiol; Female; gamma-Aminob | 2017 |
GnRH dysregulation in polycystic ovarian syndrome (PCOS) is a manifestation of an altered neurotransmitter profile.
Topics: Acetylcholine; Animals; Dopamine; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Gona | 2018 |
Activation of arcuate nucleus GABA neurons promotes luteinizing hormone secretion and reproductive dysfunction: Implications for polycystic ovary syndrome.
Topics: Androgens; Animals; Arcuate Nucleus of Hypothalamus; Brain; Disease Models, Animal; Female; GABAergi | 2019 |
Neurotransmitter alteration in a testosterone propionate-induced polycystic ovarian syndrome rat model.
Topics: Animals; Disease Models, Animal; Dopamine; Epinephrine; Female; gamma-Aminobutyric Acid; Glucose Tol | 2017 |
Prenatal androgens alter GABAergic drive to gonadotropin-releasing hormone neurons: implications for a common fertility disorder.
Topics: Androgens; Animals; Estrous Cycle; Female; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Gonado | 2004 |