Page last updated: 2024-10-16

gamma-aminobutyric acid and Polycystic Ovarian Syndrome

gamma-aminobutyric acid has been researched along with Polycystic Ovarian Syndrome in 11 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Research Excerpts

ExcerptRelevanceReference
" The study was undertaken to investigate the possible protective and ameliorating effects of GABA in Letrozole induced PCOS model in rats by targeting insulin resistance."7.85Protective effects of GABA against metabolic and reproductive disturbances in letrozole induced polycystic ovarian syndrome in rats. ( Afsar, T; Almajwal, A; Jahan, S; Pirzada, M; Rauf, N; Razak, S; Ullah, A; Ullah, H, 2017)
" The study was undertaken to investigate the possible protective and ameliorating effects of GABA in Letrozole induced PCOS model in rats by targeting insulin resistance."3.85Protective effects of GABA against metabolic and reproductive disturbances in letrozole induced polycystic ovarian syndrome in rats. ( Afsar, T; Almajwal, A; Jahan, S; Pirzada, M; Rauf, N; Razak, S; Ullah, A; Ullah, H, 2017)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's6 (54.55)24.3611
2020's4 (36.36)2.80

Authors

AuthorsStudies
Szeliga, A1
Rudnicka, E1
Maciejewska-Jeske, M1
Kucharski, M1
Kostrzak, A1
Hajbos, M1
Niwczyk, O1
Smolarczyk, R1
Meczekalski, B1
Silva, MSB2
Campbell, RE2
Eepho, OI1
Bashir, AM1
Oniyide, AA1
Aturamu, A1
Owolabi, OV1
Ajadi, IO1
Fafure, AA1
Ajadi, MB1
Areloegbe, SE1
Olaniyi, KS1
Liang, Z1
Di, N1
Li, L1
Yang, D1
Kawwass, JF1
Sanders, KM1
Loucks, TL1
Rohan, LC1
Berga, SL1
Holmberg, E1
Sjöstedt, J1
Malinina, E1
Johansson, M1
Turkmen, S1
Ragagnin, G1
Lundqvist, A1
Löfgren, M1
Jaukkuri, L1
Bixo, M1
Bäckström, T1
Ullah, A1
Jahan, S1
Razak, S1
Pirzada, M1
Ullah, H1
Almajwal, A1
Rauf, N1
Afsar, T1
Chaudhari, N1
Dawalbhakta, M1
Nampoothiri, L1
Desroziers, E1
Hessler, S1
Prescott, M1
Coyle, C1
Herbison, AE1
Chaudhari, NK1
Nampoothiri, LP1
Sullivan, SD1
Moenter, SM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pathogenesis of Functional Hypothalamic Amenorrhea[NCT01674426]17 participants (Actual)Interventional1997-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for gamma-aminobutyric acid and Polycystic Ovarian Syndrome

ArticleYear
Neuroendocrine Determinants of Polycystic Ovary Syndrome.
    International journal of environmental research and public health, 2022, 03-06, Volume: 19, Issue:5

    Topics: Acetylcholine; Dopamine; Female; Galanin; gamma-Aminobutyric Acid; Glutamic Acid; Gonadotropin-Relea

2022
Allopregnanolone involvement in feeding regulation, overeating and obesity.
    Frontiers in neuroendocrinology, 2018, Volume: 48

    Topics: Animals; Female; gamma-Aminobutyric Acid; Humans; Hyperphagia; Obesity; Polycystic Ovary Syndrome; P

2018

Other Studies

9 other studies available for gamma-aminobutyric acid and Polycystic Ovarian Syndrome

ArticleYear
Polycystic Ovary Syndrome and the Neuroendocrine Consequences of Androgen Excess.
    Comprehensive Physiology, 2022, 03-29, Volume: 12, Issue:2

    Topics: Adult; Androgens; Animals; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Humans;

2022
Modulation of GABA by sodium butyrate ameliorates hypothalamic inflammation in experimental model of PCOS.
    BMC neuroscience, 2023, Nov-23, Volume: 24, Issue:1

    Topics: Animals; Butyric Acid; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Humans; Letrozole; M

2023
Gut microbiota alterations reveal potential gut-brain axis changes in polycystic ovary syndrome.
    Journal of endocrinological investigation, 2021, Volume: 44, Issue:8

    Topics: Adult; Bacteria; Brain-Gut Axis; Dysbiosis; Feces; Female; Follicle Stimulating Hormone; gamma-Amino

2021
Increased cerebrospinal fluid levels of GABA, testosterone and estradiol in women with polycystic ovary syndrome.
    Human reproduction (Oxford, England), 2017, 07-01, Volume: 32, Issue:7

    Topics: Adult; Androstenedione; Cross-Sectional Studies; Estradiol; Female; gamma-Aminobutyric Acid; Glucose

2017
Protective effects of GABA against metabolic and reproductive disturbances in letrozole induced polycystic ovarian syndrome in rats.
    Journal of ovarian research, 2017, Sep-15, Volume: 10, Issue:1

    Topics: Androgen Antagonists; Animals; Blood Glucose; Body Weight; Catalase; Estradiol; Female; gamma-Aminob

2017
GnRH dysregulation in polycystic ovarian syndrome (PCOS) is a manifestation of an altered neurotransmitter profile.
    Reproductive biology and endocrinology : RB&E, 2018, Apr-11, Volume: 16, Issue:1

    Topics: Acetylcholine; Animals; Dopamine; Female; Frontal Lobe; gamma-Aminobutyric Acid; Glutamic Acid; Gona

2018
Activation of arcuate nucleus GABA neurons promotes luteinizing hormone secretion and reproductive dysfunction: Implications for polycystic ovary syndrome.
    EBioMedicine, 2019, Volume: 44

    Topics: Androgens; Animals; Arcuate Nucleus of Hypothalamus; Brain; Disease Models, Animal; Female; GABAergi

2019
Neurotransmitter alteration in a testosterone propionate-induced polycystic ovarian syndrome rat model.
    Hormone molecular biology and clinical investigation, 2017, Feb-01, Volume: 29, Issue:2

    Topics: Animals; Disease Models, Animal; Dopamine; Epinephrine; Female; gamma-Aminobutyric Acid; Glucose Tol

2017
Prenatal androgens alter GABAergic drive to gonadotropin-releasing hormone neurons: implications for a common fertility disorder.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, May-04, Volume: 101, Issue:18

    Topics: Androgens; Animals; Estrous Cycle; Female; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Gonado

2004