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gamma-aminobutyric acid and Poisoning, Lead

gamma-aminobutyric acid has been researched along with Poisoning, Lead in 19 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Research Excerpts

ExcerptRelevanceReference
"Environmental factors have been associated with psychiatric disorders and recent epidemiological studies suggest an association between prenatal lead (Pb(2+)) exposure and schizophrenia (SZ)."7.81Early-life lead exposure recapitulates the selective loss of parvalbumin-positive GABAergic interneurons and subcortical dopamine system hyperactivity present in schizophrenia. ( Guilarte, TR; Liu, X; McGlothan, JL; Ruby, KN; Soares, BD; Stansfield, KH, 2015)
"Environmental factors have been associated with psychiatric disorders and recent epidemiological studies suggest an association between prenatal lead (Pb(2+)) exposure and schizophrenia (SZ)."3.81Early-life lead exposure recapitulates the selective loss of parvalbumin-positive GABAergic interneurons and subcortical dopamine system hyperactivity present in schizophrenia. ( Guilarte, TR; Liu, X; McGlothan, JL; Ruby, KN; Soares, BD; Stansfield, KH, 2015)
"This study suggests that postnatal lead toxicity in autistic patients of Saudi Arabia could represent a causative factor in the pathogenesis of autism."3.77Relationship between chronic lead toxicity and plasma neurotransmitters in autistic patients from Saudi Arabia. ( Ayahdi, LYA; Bacha, AB; El-Ansary, AK, 2011)
"Wistar rat pups were administered either a high dose of lead acetate (400 micrograms lead/g body weight/day) or a low dose (100 micrograms lead/g body weight/day) by gastric intubation, from 2 days through 60 days of age."3.68Regional alterations of brain biogenic amines and GABA/glutamate levels in rats following chronic lead exposure during neonatal development. ( Desiraju, T; Shailesh Kumar, MV, 1990)
"A detailed case history of lead poisoning in a young infant is presented."3.67Lead-induced convulsions in young infants--a case history and the role of GABA and sodium valproate in the pathogenesis and treatment. ( Aslam, M; Fernando, NP; Harrison, PG; Healy, MA, 1984)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19909 (47.37)18.7374
1990's4 (21.05)18.2507
2000's2 (10.53)29.6817
2010's3 (15.79)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Cai, QL1
Peng, DJ1
Chen, JW1
Luo, HL1
Ou, SY1
Huang, ML1
Jiang, YM1
Stansfield, KH1
Ruby, KN1
Soares, BD1
McGlothan, JL1
Liu, X1
Guilarte, TR1
Zhang, R1
Lu, H1
Tian, S1
Yin, J1
Chen, Q1
Ma, L1
Cui, S1
Niu, Y1
El-Ansary, AK1
Bacha, AB1
Ayahdi, LYA1
Leret, ML1
Garcia-Uceda, F1
Antonio, MT1
Fitsanakis, VA1
Aschner, M1
Silbergeld, EK4
Lamon, JM1
Govoni, S1
Memo, M1
Lucchi, L1
Spano, PF1
Trabucchi, M1
Skorka, G1
Bien, E1
Beritić, T1
Healy, MA1
Aslam, M1
Harrison, PG1
Fernando, NP1
Hruska, RE1
Miller, LP2
Eng, N2
Jabłońska, L1
Walski, M1
Rafałowska, U1
Solliway, BM1
Schaffer, A1
Pratt, H1
Mittelman, N1
Yannai, S1
Lasley, SM1
Gilbert, ME1
Kennedy, S1
Shailesh Kumar, MV1
Desiraju, T1
Moore, MR1
McIntosh, MJ1
Bushnell, IW1

Reviews

4 reviews available for gamma-aminobutyric acid and Poisoning, Lead

ArticleYear
The importance of glutamate, glycine, and gamma-aminobutyric acid transport and regulation in manganese, mercury and lead neurotoxicity.
    Toxicology and applied pharmacology, 2005, May-01, Volume: 204, Issue:3

    Topics: Animals; Biological Transport; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Humans; Kidney Disea

2005
[Neurotoxicologic effects of lead and mercury].
    Die Pharmazie, 1983, Volume: 38, Issue:11

    Topics: Animals; Dopamine; gamma-Aminobutyric Acid; Humans; Lead Poisoning; Mercury Poisoning; Nervous Syste

1983
Lead neuropathy.
    Critical reviews in toxicology, 1984, Volume: 12, Issue:2

    Topics: Aminolevulinic Acid; Animals; Electromyography; Electrophysiology; gamma-Aminobutyric Acid; Humans;

1984
The neurotoxicology of lead.
    Neurotoxicology, 1986,Summer, Volume: 7, Issue:2

    Topics: Amino Acids; Aminolevulinic Acid; Animals; Biopterins; Brain; Child; Energy Metabolism; gamma-Aminob

1986

Other Studies

15 other studies available for gamma-aminobutyric acid and Poisoning, Lead

ArticleYear
Impact of Lead Exposure on Thyroid Status and IQ Performance among School-age Children Living Nearby a Lead-Zinc Mine in China.
    Neurotoxicology, 2021, Volume: 82

    Topics: Child; China; Diet, Healthy; Drinking Water; Female; gamma-Aminobutyric Acid; Glutamic Acid; Humans;

2021
Early-life lead exposure recapitulates the selective loss of parvalbumin-positive GABAergic interneurons and subcortical dopamine system hyperactivity present in schizophrenia.
    Translational psychiatry, 2015, Mar-10, Volume: 5

    Topics: Animals; Blotting, Western; Brain; Chromatography, High Pressure Liquid; Dopamine; Female; gamma-Ami

2015
Protective effects of pre-germinated brown rice diet on low levels of Pb-induced learning and memory deficits in developing rat.
    Chemico-biological interactions, 2010, Mar-30, Volume: 184, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Brain; Deoxyguanosine; Diet; Female; gamma-Aminobutyric Acid;

2010
Relationship between chronic lead toxicity and plasma neurotransmitters in autistic patients from Saudi Arabia.
    Clinical biochemistry, 2011, Volume: 44, Issue:13

    Topics: Autistic Disorder; Case-Control Studies; Child; Child, Preschool; Dopamine; Erythrocytes; gamma-Amin

2011
Effects of maternal lead administration on monoaminergic, GABAergic and glutamatergic systems.
    Brain research bulletin, 2002, Sep-15, Volume: 58, Issue:5

    Topics: Animals; Biogenic Monoamines; Brain; Cerebral Cortex; Corpus Striatum; Dopamine; Female; gamma-Amino

2002
Role of altered heme synthesis in lead neurotoxicity.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1980, Volume: 22, Issue:10

    Topics: Aminolevulinic Acid; gamma-Aminobutyric Acid; Heme; Humans; Lead Poisoning; Nervous System Diseases;

1980
Brain neurotransmitter system and chronic lead intoxication.
    Pharmacological research communications, 1980, Volume: 12, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Weight; Brain; Cyclic GMP; Female; gamma-Aminobutyric

1980
Indirectly acting neurotoxins.
    Acta psychiatrica Scandinavica. Supplementum, 1983, Volume: 303

    Topics: Aminolevulinic Acid; Animals; Brain; Dopamine; Estradiol; Female; gamma-Aminobutyric Acid; Lead Pois

1983
Lead-induced convulsions in young infants--a case history and the role of GABA and sodium valproate in the pathogenesis and treatment.
    Journal of clinical and hospital pharmacy, 1984, Volume: 9, Issue:3

    Topics: Chemical Phenomena; Chemistry; Citric Acid Cycle; gamma-Aminobutyric Acid; Humans; Infant; Lead; Lea

1984
Effects of lead in vivo and in vitro on GABAergic neurochemistry.
    Journal of neurochemistry, 1980, Volume: 34, Issue:6

    Topics: Animals; Binding Sites; Brain; Carboxy-Lyases; Female; gamma-Aminobutyric Acid; Glutamate Decarboxyl

1980
Lead as an inductor of some morphological and functional changes in synaptosomes from rat brain.
    Cellular and molecular neurobiology, 1994, Volume: 14, Issue:6

    Topics: Animals; Biological Transport; Dopamine; gamma-Aminobutyric Acid; Histamine; Histidine; Lead; Lead P

1994
Visual evoked potentials N75 and P100 latencies correlate with urinary delta-aminolevulinic acid, suggesting gamma-aminobutyric acid involvement in their generation.
    Journal of the neurological sciences, 1995, Volume: 134, Issue:1-2

    Topics: Aminolevulinic Acid; Case-Control Studies; Evoked Potentials, Visual; gamma-Aminobutyric Acid; Human

1995
Presynaptic glutamatergic function in dentate gyrus in vivo is diminished by chronic exposure to inorganic lead.
    Brain research, 1996, Oct-14, Volume: 736, Issue:1-2

    Topics: Animals; Animals, Newborn; Animals, Suckling; Calcium; Dentate Gyrus; Dizocilpine Maleate; Electric

1996
Lead, GABA, and seizures: effects of subencephalopathic lead exposure on seizure sensitivity and GABAergic function.
    Environmental research, 1979, Volume: 19, Issue:2

    Topics: 4-Aminobutyrate Transaminase; Animals; Animals, Newborn; Blood-Brain Barrier; Convulsants; Female; g

1979
Regional alterations of brain biogenic amines and GABA/glutamate levels in rats following chronic lead exposure during neonatal development.
    Archives of toxicology, 1990, Volume: 64, Issue:4

    Topics: Animals; Biogenic Amines; Body Weight; Brain; Dopamine; Dose-Response Relationship, Drug; Female; ga

1990