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gamma-aminobutyric acid and Pituitary Neoplasms

gamma-aminobutyric acid has been researched along with Pituitary Neoplasms in 10 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.

Research Excerpts

ExcerptRelevanceReference
"gamma-Aminobutyric acid (GABA) is an important regulatory factor of pituitary gland function, which in addition to hypothalamic neurons, can be derived from intrapituitary sources, ie, growth hormone (GH) cells of rat and monkey."5.33Receptors and sites of synthesis and storage of gamma-aminobutyric acid in human pituitary glands and in growth hormone adenomas. ( End, K; Gamel-Didelon, K; Gratzl, M; Jung, H; Lüdecke, D; Mayerhofer, A; Tolnay, M, 2005)
"Fifteen patients with prolactinomas, 8 patients with non-tumoral hyperprolactinemia and 10 healthy subjects were studied: in non consecutive days, all subjects received placebo and SV at the dose of 400 and 800 mg po."2.68Different sensitivity to sodium valproate in healthy, non-tumoral and tumoral hyperprolactinemic subjects. ( Colao, A; Di Sarno, A; Di Somma, C; Ferone, D; Landi, ML; Lombardi, G; Merola, B; Sarnacchiaro, F; Tolino, A, 1997)
"gamma-Aminobutyric acid (GABA) is an important regulatory factor of pituitary gland function, which in addition to hypothalamic neurons, can be derived from intrapituitary sources, ie, growth hormone (GH) cells of rat and monkey."1.33Receptors and sites of synthesis and storage of gamma-aminobutyric acid in human pituitary glands and in growth hormone adenomas. ( End, K; Gamel-Didelon, K; Gratzl, M; Jung, H; Lüdecke, D; Mayerhofer, A; Tolnay, M, 2005)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19908 (80.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
End, K1
Gamel-Didelon, K1
Jung, H1
Tolnay, M1
Lüdecke, D1
Gratzl, M1
Mayerhofer, A1
Jones, MT1
Gillham, B1
Beckford, U1
Dornhorst, A1
Abraham, RR1
Seed, M1
Wynn, V1
Lamberts, SW2
Verleun, T1
Bons, EG1
Uitterlinden, P1
Oosterom, R1
Melis, GB1
Paoletti, AM1
Mais, V1
Mastrapasqua, NM1
Strigini, F1
Fruzzetti, F1
Guarnieri, G1
Gambacciani, M1
Fioretti, P1
Dufy, B2
Israel, JM2
Zyzek, E1
Dufy-Barbe, L1
Guerin, J1
Fleury, H1
Vincent, JD2
Gourdji, D1
Sarnacchiaro, F1
Colao, A1
Merola, B1
Di Sarno, A1
Landi, ML1
Di Somma, C1
Ferone, D1
Tolino, A1
Lombardi, G1
Klijn, JG1
Birkenhäger, JC1
Boyd, AE1
Reichlin, S1
Le Dafniet, M1
Garnier, P1
Bression, D1
Brandi, AM1
Racadot, J1
Peillon, F1

Reviews

1 review available for gamma-aminobutyric acid and Pituitary Neoplasms

ArticleYear
[Prolactin].
    Nederlands tijdschrift voor geneeskunde, 1978, Sep-09, Volume: 122, Issue:36

    Topics: Adenoma; Adult; Amenorrhea; Breast Neoplasms; Dopamine; Estrogens; Female; gamma-Aminobutyric Acid;

1978

Trials

1 trial available for gamma-aminobutyric acid and Pituitary Neoplasms

ArticleYear
Different sensitivity to sodium valproate in healthy, non-tumoral and tumoral hyperprolactinemic subjects.
    Journal of endocrinological investigation, 1997, Volume: 20, Issue:9

    Topics: Adolescent; Adult; Female; GABA Agents; gamma-Aminobutyric Acid; Humans; Hyperprolactinemia; Kinetic

1997

Other Studies

8 other studies available for gamma-aminobutyric acid and Pituitary Neoplasms

ArticleYear
Receptors and sites of synthesis and storage of gamma-aminobutyric acid in human pituitary glands and in growth hormone adenomas.
    American journal of clinical pathology, 2005, Volume: 124, Issue:4

    Topics: Adenoma; gamma-Aminobutyric Acid; Gene Expression Regulation, Neoplastic; Growth Hormone; Humans; Im

2005
Effect of treatment with sodium valproate and diazepam on plasma corticotropin in Nelson's syndrome.
    Lancet (London, England), 1981, May-30, Volume: 1, Issue:8231

    Topics: Adrenocorticotropic Hormone; Adult; Depression, Chemical; Diazepam; Female; gamma-Aminobutyric Acid;

1981
Effect of cyproheptadine, desmethylcyproheptadine, gamma-amino-butyric acid and sodium valproate on adrenocorticotrophin secretion by cultured pituitary tumour cells from three patients with Nelson's syndrome.
    The Journal of endocrinology, 1983, Volume: 96, Issue:3

    Topics: Adrenocorticotropic Hormone; Cyproheptadine; Female; gamma-Aminobutyric Acid; Humans; Nelson Syndrom

1983
The effects of the gabaergic drug, sodium valproate, on prolactin secretion in normal and hyperprolactinemic subjects.
    The Journal of clinical endocrinology and metabolism, 1982, Volume: 54, Issue:3

    Topics: Adenoma; Adult; Female; Follicular Phase; gamma-Aminobutyric Acid; Humans; Kinetics; Male; Middle Ag

1982
An electrophysiological study of cultured human pituitary cells.
    Molecular and cellular endocrinology, 1982, Volume: 27, Issue:2

    Topics: Action Potentials; Adenoma; Calcium; Cells, Cultured; Dopamine; Electrophysiology; gamma-Aminobutyri

1982
Effects of GABA on electrical properties of cultured rat pituitary tumor cells: an intracellular recording study.
    Life sciences, 1981, Jul-27, Volume: 29, Issue:4

    Topics: Action Potentials; Animals; Bicuculline; Clone Cells; Furosemide; GABA Antagonists; gamma-Aminobutyr

1981
Neural control of prolactin secretion in man.
    Psychoneuroendocrinology, 1978, Volume: 3, Issue:2

    Topics: Adenoma; Animals; Dopamine; Female; gamma-Aminobutyric Acid; Homeostasis; Humans; Hypothalamo-Hypoph

1978
Correlative studies between the presence of thyrotropin-releasing hormone (TRH) receptors and the in vitro stimulation of growth-hormone (GH) secretion in human GH-secreting adenomas.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1985, Volume: 17, Issue:9

    Topics: Adenoma; Cell Membrane; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Growth Hormone; Hum

1985