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gamma-aminobutyric acid and Phobic Disorders

gamma-aminobutyric acid has been researched along with Phobic Disorders in 23 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Phobic Disorders: Anxiety disorders in which the essential feature is persistent and irrational fear of a specific object, activity, or situation that the individual feels compelled to avoid. The individual recognizes the fear as excessive or unreasonable.

Research Excerpts

ExcerptRelevanceReference
" Further studies are required to confirm this effect and to determine whether a dose-response relationship exists."2.69Treatment of social phobia with gabapentin: a placebo-controlled study. ( Davidson, JR; Greist, JH; Janney, CA; Jefferson, JW; Katzelnick, DJ; Pande, AC; Sutherland, SM; Weisler, RH, 1999)
"Pharmacologic treatments for panic disorder and social phobia have been available since the early 1960s."2.40Panic disorder and social phobia: current treatments and new strategies. ( Connor, KM; Davidson, JR; Sutherland, SM, 1998)
"Excessive sweating (hyperhidrosis) is an overlooked and potentially disabling symptom, which is often seen in social anxiety disorder (SAD)."1.31Hyperhidrosis in social anxiety disorder. ( Churchill, LE; Connor, KM; Davidson, JR; Foa, EB, 2002)
"We conclude that hyperhidrosis is frequently seen in patients with SAD, and that its response to treatment is variable."1.31Hyperhidrosis in social anxiety disorder. ( Churchill, LE; Connor, KM; Davidson, JR; Foa, EB, 2002)
"Hyperhidrosis was found in 24."1.31Hyperhidrosis in social anxiety disorder. ( Churchill, LE; Connor, KM; Davidson, JR; Foa, EB, 2002)
"Amphetamine, 1 mg/kg, was then combined with ineffective doses of GAG and progabide (50 and 100 mg/kg, respectively)."1.30Interactions between dopamine and GABA in the control of ambulatory activity and neophobia in the mouse. ( Agmo, A; Belzung, C, 1998)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's6 (26.09)18.2507
2000's12 (52.17)29.6817
2010's4 (17.39)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kawalec, P1
Cierniak, A1
Pilc, A1
Nowak, G1
Chutko, LS2
Surushkina, SIu1
Iakovenko, EA1
Nikishena, IS1
Anisimova, TI2
Bondarchuk, IuL1
Surushkina, SY1
Greist, JH2
Liu-Dumaw, M1
Schweizer, E1
Feltner, D1
Davidson, JR4
Foa, EB1
Connor, KM3
Churchill, LE1
Blanco, C1
Schneier, FR1
Schmidt, A1
Blanco-Jerez, CR1
Marshall, RD1
Sánchez-Lacay, A1
Liebowitz, MR1
Pigott, TA1
Ameli, R1
Snow, J1
Rakocevic, G1
Dalakas, MC1
Abdou, AM1
Higashiguchi, S1
Horie, K1
Kim, M1
Hatta, H1
Yokogoshi, H1
Biermann, T1
Bleich, S1
Kornhuber, J1
Hillemacher, T1
Agmo, A1
Belzung, C1
Pollack, MH1
Matthews, J1
Scott, EL1
Pande, AC1
Jefferson, JW2
Janney, CA1
Katzelnick, DJ1
Weisler, RH1
Sutherland, SM2
Sutherland, S1
Weisler, R1
van Ameringen, M1
Mancini, C1
Farvolden, P1
Oakman, J1
Li, D1
Chokka, P1
Tibbo, P1
Argyropoulos, SV1
Bell, CJ1
Nutt, DJ1
Durkin, JP1
Hoehn-Saric, R1
McLeod, DR1

Reviews

10 reviews available for gamma-aminobutyric acid and Phobic Disorders

ArticleYear
Pregabalin for the treatment of social anxiety disorder.
    Expert opinion on investigational drugs, 2015, Volume: 24, Issue:4

    Topics: Anti-Anxiety Agents; gamma-Aminobutyric Acid; Humans; Phobic Disorders; Pregabalin; Quality of Life;

2015
[Anxiety and fear in children and adolescents].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2016, Volume: 116, Issue:1

    Topics: Adolescent; Child; Fear; Female; gamma-Aminobutyric Acid; Humans; Male; Phobic Disorders; Tranquiliz

2016
Pharmacological treatment of social anxiety disorder: a meta-analysis.
    Depression and anxiety, 2003, Volume: 18, Issue:1

    Topics: Acetates; Amines; Anti-Anxiety Agents; Antidepressive Agents; Antimanic Agents; Anxiety Disorders; C

2003
Anxiety disorders in women.
    The Psychiatric clinics of North America, 2003, Volume: 26, Issue:3

    Topics: Agoraphobia; Anti-Anxiety Agents; Anxiety Disorders; Comorbidity; Female; gamma-Aminobutyric Acid; H

2003
Social phobia: issues in assessment and management.
    Epilepsia, 1999, Volume: 40 Suppl 6

    Topics: Acetates; Amines; Anticonvulsants; Benzodiazepines; Cyclohexanecarboxylic Acids; Gabapentin; gamma-A

1999
Drugs in development for social anxiety disorder: more to social anxiety than meets the SSRI.
    Expert opinion on investigational drugs, 2000, Volume: 9, Issue:10

    Topics: Animals; Anxiety Disorders; Dopamine; gamma-Aminobutyric Acid; Humans; Monoamine Oxidase Inhibitors;

2000
Toward an integrative understanding of social phobia.
    Journal of psychiatry & neuroscience : JPN, 2001, Volume: 26, Issue:3

    Topics: Animals; Brain; Disease Models, Animal; gamma-Aminobutyric Acid; Genetic Predisposition to Disease;

2001
Brain function in social anxiety disorder.
    The Psychiatric clinics of North America, 2001, Volume: 24, Issue:4

    Topics: Anxiety; Anxiety Disorders; Brain; Dopamine; gamma-Aminobutyric Acid; Human Growth Hormone; Humans;

2001
Panic disorder and social phobia: current treatments and new strategies.
    Cleveland Clinic journal of medicine, 1998, Volume: 65 Suppl 1

    Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Cost-Benefit Analysis; Cycl

1998
Generalized anxiety disorder.
    The Psychiatric clinics of North America, 1985, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyc

1985

Trials

3 trials available for gamma-aminobutyric acid and Phobic Disorders

ArticleYear
Efficacy of pregabalin in preventing relapse in patients with generalized social anxiety disorder: results of a double-blind, placebo-controlled 26-week study.
    International clinical psychopharmacology, 2011, Volume: 26, Issue:5

    Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Follow-Up Studies; gamma-Aminobutyric Acid; Hu

2011
Relaxation and immunity enhancement effects of gamma-aminobutyric acid (GABA) administration in humans.
    BioFactors (Oxford, England), 2006, Volume: 26, Issue:3

    Topics: Administration, Oral; Adult; Anxiety; Electroencephalography; Female; GABA Agents; gamma-Aminobutyri

2006
Treatment of social phobia with gabapentin: a placebo-controlled study.
    Journal of clinical psychopharmacology, 1999, Volume: 19, Issue:4

    Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Double-Blind Method; Fema

1999

Other Studies

10 other studies available for gamma-aminobutyric acid and Phobic Disorders

ArticleYear
[Cognitive and emotional impairments in patients with protracted anxiety-phobic disorders].
    Terapevticheskii arkhiv, 2014, Volume: 86, Issue:12

    Topics: Acute Disease; Adolescent; Adult; Chronic Disease; Cognition Disorders; gamma-Aminobutyric Acid; Hum

2014
Hyperhidrosis in social anxiety disorder.
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:7-8

    Topics: Acetates; Adult; Amines; Calcium Channel Blockers; Clinical Trials as Topic; Clonazepam; Cognitive B

2002
A neuropsychological assessment of phobias in patients with stiff person syndrome.
    Neurology, 2005, Jun-14, Volume: 64, Issue:11

    Topics: Accidental Falls; Adult; Anxiety Disorders; Brain; Brain Chemistry; Cognition Disorders; Female; gam

2005
Pregabalin: new indication. Generalised anxiety: better to use benzodiazepine.
    Prescrire international, 2007, Volume: 16, Issue:89

    Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Benzodiazepines; Clinical Trials as Topic; Dru

2007
Pregabalin in benzodiazepine withdrawal.
    Pharmacopsychiatry, 2007, Volume: 40, Issue:6

    Topics: Adult; Alprazolam; Anticonvulsants; Anxiety Disorders; gamma-Aminobutyric Acid; Humans; Hypnotics an

2007
Interactions between dopamine and GABA in the control of ambulatory activity and neophobia in the mouse.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 59, Issue:1

    Topics: Amphetamine; Animals; Chi-Square Distribution; Dopamine; Dopamine Agents; Exploratory Behavior; GABA

1998
Gabapentin as a potential treatment for anxiety disorders.
    The American journal of psychiatry, 1998, Volume: 155, Issue:7

    Topics: Acetates; Adult; Alprazolam; Amines; Anticonvulsants; Anxiety Disorders; Cyclohexanecarboxylic Acids

1998
Gabapentin. CI 945, GOE 3450, Neurontin.
    Drugs in R&D, 1999, Volume: 2, Issue:6

    Topics: Acetates; Adult; Amines; Anticonvulsants; Area Under Curve; Biological Availability; Child; Child, P

1999
Benzodiazepines and anticonvulsants for social phobia (social anxiety disorder).
    The Journal of clinical psychiatry, 2001, Volume: 62 Suppl 1

    Topics: Acetates; Alprazolam; Amines; Anticonvulsants; Benzodiazepines; Clinical Trials as Topic; Clonazepam

2001
Gabapentin in complicated school refusal.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2002, Volume: 41, Issue:6

    Topics: Acetates; Adolescent; Amines; Comorbidity; Cyclohexanecarboxylic Acids; Cyclohexanols; Drug Therapy,

2002