gamma-aminobutyric acid has been researched along with Phantom Limb in 14 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Phantom Limb: Perception of painful and nonpainful phantom sensations that occur following the complete or partial loss of a limb. The majority of individuals with an amputated extremity will experience the impression that the limb is still present, and in many cases, painful. (From Neurol Clin 1998 Nov;16(4):919-36; Brain 1998 Sep;121(Pt 9):1603-30)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The risk of phantom pain (gabapentin vs." | 9.12 | A randomized study of the effects of gabapentin on postamputation pain. ( Finnerup, NB; Jensen, TS; Keller, J; Kramp, S; Nikolajsen, L; Vimtrup, AS, 2006) |
| "Gabapentin administered in the first 30 postoperative days after amputation does not reduce the incidence or intensity of postamputation pain." | 9.12 | A randomized study of the effects of gabapentin on postamputation pain. ( Finnerup, NB; Jensen, TS; Keller, J; Kramp, S; Nikolajsen, L; Vimtrup, AS, 2006) |
| "To evaluate the effectiveness of gabapentin in adults with phantom limb pain." | 8.88 | Efficacy of gabapentin for treatment of adults with phantom limb pain. ( Abbass, K, 2012) |
| "A PubMed search (1966-September 2012) was conducted using the key words phantom limb pain and gabapentin." | 8.88 | Efficacy of gabapentin for treatment of adults with phantom limb pain. ( Abbass, K, 2012) |
| "Randomized controlled trials that studied the effectiveness of gabapentin in adults with phantom limb pain were identified and selected." | 8.88 | Efficacy of gabapentin for treatment of adults with phantom limb pain. ( Abbass, K, 2012) |
| "Given the results of these trials, oral gabapentin in patients aged 18 years or older may decrease phantom limb pain." | 8.88 | Efficacy of gabapentin for treatment of adults with phantom limb pain. ( Abbass, K, 2012) |
| "To describe a case of gabapentin-induced coma that was reversed with flumazenil and hemodialysis." | 7.72 | Flumazenil and dialysis for gabapentin-induced coma. ( Amsden, GW; Butler, TC; Rosen, RM; Wallace, AL, 2003) |
| " To our knowledge, this is the first documented case of not only gabapentin-induced coma, but also the effectiveness of flumazenil for treatment of this type of coma." | 7.72 | Flumazenil and dialysis for gabapentin-induced coma. ( Amsden, GW; Butler, TC; Rosen, RM; Wallace, AL, 2003) |
| "We describe an 83-year-old dialysis-dependent white man who became comatose after a single dose of gabapentin for phantom limb pain." | 7.72 | Flumazenil and dialysis for gabapentin-induced coma. ( Amsden, GW; Butler, TC; Rosen, RM; Wallace, AL, 2003) |
| "Seven children and young adults with phantom limb pain (PLP) were treated with gabapentin." | 7.71 | Gabapentin in phantom limb pain management in children and young adults: report of seven cases. ( Rusy, LM; Troshynski, TJ; Weisman, SJ, 2001) |
| "The intensity of stump and phantom pain was recorded every day on a numeric rating scale (0-10) during the 30-day treatment period." | 6.72 | A randomized study of the effects of gabapentin on postamputation pain. ( Finnerup, NB; Jensen, TS; Keller, J; Kramp, S; Nikolajsen, L; Vimtrup, AS, 2006) |
| "The risk of phantom pain (gabapentin vs." | 6.72 | A randomized study of the effects of gabapentin on postamputation pain. ( Finnerup, NB; Jensen, TS; Keller, J; Kramp, S; Nikolajsen, L; Vimtrup, AS, 2006) |
| "Seven children and young adults with phantom limb pain (PLP) were treated with gabapentin." | 5.31 | Gabapentin in phantom limb pain management in children and young adults: report of seven cases. ( Rusy, LM; Troshynski, TJ; Weisman, SJ, 2001) |
| " The risk of phantom pain (gabapentin vs." | 5.12 | A randomized study of the effects of gabapentin on postamputation pain. ( Finnerup, NB; Jensen, TS; Keller, J; Kramp, S; Nikolajsen, L; Vimtrup, AS, 2006) |
| "Gabapentin administered in the first 30 postoperative days after amputation does not reduce the incidence or intensity of postamputation pain." | 5.12 | A randomized study of the effects of gabapentin on postamputation pain. ( Finnerup, NB; Jensen, TS; Keller, J; Kramp, S; Nikolajsen, L; Vimtrup, AS, 2006) |
| "To evaluate the effectiveness of gabapentin in adults with phantom limb pain." | 4.88 | Efficacy of gabapentin for treatment of adults with phantom limb pain. ( Abbass, K, 2012) |
| "A PubMed search (1966-September 2012) was conducted using the key words phantom limb pain and gabapentin." | 4.88 | Efficacy of gabapentin for treatment of adults with phantom limb pain. ( Abbass, K, 2012) |
| "Randomized controlled trials that studied the effectiveness of gabapentin in adults with phantom limb pain were identified and selected." | 4.88 | Efficacy of gabapentin for treatment of adults with phantom limb pain. ( Abbass, K, 2012) |
| "Given the results of these trials, oral gabapentin in patients aged 18 years or older may decrease phantom limb pain." | 4.88 | Efficacy of gabapentin for treatment of adults with phantom limb pain. ( Abbass, K, 2012) |
| "To describe a case of gabapentin-induced coma that was reversed with flumazenil and hemodialysis." | 3.72 | Flumazenil and dialysis for gabapentin-induced coma. ( Amsden, GW; Butler, TC; Rosen, RM; Wallace, AL, 2003) |
| " To our knowledge, this is the first documented case of not only gabapentin-induced coma, but also the effectiveness of flumazenil for treatment of this type of coma." | 3.72 | Flumazenil and dialysis for gabapentin-induced coma. ( Amsden, GW; Butler, TC; Rosen, RM; Wallace, AL, 2003) |
| "We describe an 83-year-old dialysis-dependent white man who became comatose after a single dose of gabapentin for phantom limb pain." | 3.72 | Flumazenil and dialysis for gabapentin-induced coma. ( Amsden, GW; Butler, TC; Rosen, RM; Wallace, AL, 2003) |
| "Seven children and young adults with phantom limb pain (PLP) were treated with gabapentin." | 3.71 | Gabapentin in phantom limb pain management in children and young adults: report of seven cases. ( Rusy, LM; Troshynski, TJ; Weisman, SJ, 2001) |
| "Phantom limb pain is a debilitating condition for which no effective treatment has been found." | 2.82 | Phantom motor execution facilitated by machine learning and augmented reality as treatment for phantom limb pain: a single group, clinical trial in patients with chronic intractable phantom limb pain. ( Burger, H; Caine-Winterberger, K; Eriksson, K; Guðmundsdóttir, RA; Hermansson, L; Kristoffersen, MB; Kulbacka-Ortiz, K; Ortiz-Catalan, M; Pihlar, Z; Ragnö, C; Stockselius, A; Widehammar, C; Zepeda-Echavarria, A, 2016) |
| "The intensity of stump and phantom pain was recorded every day on a numeric rating scale (0-10) during the 30-day treatment period." | 2.72 | A randomized study of the effects of gabapentin on postamputation pain. ( Finnerup, NB; Jensen, TS; Keller, J; Kramp, S; Nikolajsen, L; Vimtrup, AS, 2006) |
| "The risk of phantom pain (gabapentin vs." | 2.72 | A randomized study of the effects of gabapentin on postamputation pain. ( Finnerup, NB; Jensen, TS; Keller, J; Kramp, S; Nikolajsen, L; Vimtrup, AS, 2006) |
| "Amitriptyline was the only antidepressant prescribed commonly as a first-line treatment." | 1.39 | An observational descriptive study of the epidemiology and treatment of neuropathic pain in a UK general population. ( Carroll, D; Gabriel, ZL; Hall, GC; McQuay, HJ; Morant, SV, 2013) |
| "Seven children and young adults with phantom limb pain (PLP) were treated with gabapentin." | 1.31 | Gabapentin in phantom limb pain management in children and young adults: report of seven cases. ( Rusy, LM; Troshynski, TJ; Weisman, SJ, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hall, GC | 1 |
| Morant, SV | 1 |
| Carroll, D | 1 |
| Gabriel, ZL | 1 |
| McQuay, HJ | 1 |
| Roldan, CJ | 1 |
| Lesnick, JS | 1 |
| Ortiz-Catalan, M | 1 |
| Guðmundsdóttir, RA | 1 |
| Kristoffersen, MB | 1 |
| Zepeda-Echavarria, A | 1 |
| Caine-Winterberger, K | 1 |
| Kulbacka-Ortiz, K | 1 |
| Widehammar, C | 1 |
| Eriksson, K | 1 |
| Stockselius, A | 1 |
| Ragnö, C | 1 |
| Pihlar, Z | 1 |
| Burger, H | 1 |
| Hermansson, L | 1 |
| Klass, M | 1 |
| Csete, M | 1 |
| Gerlinger, I | 1 |
| Turek, T | 1 |
| Wigton, A | 1 |
| Abbass, K | 1 |
| Butler, TC | 1 |
| Rosen, RM | 1 |
| Wallace, AL | 1 |
| Amsden, GW | 1 |
| Staley, K | 1 |
| Nikolajsen, L | 1 |
| Finnerup, NB | 1 |
| Kramp, S | 1 |
| Vimtrup, AS | 1 |
| Keller, J | 1 |
| Jensen, TS | 1 |
| Ketz, AK | 2 |
| Childers, MK | 1 |
| Holland, D | 1 |
| Rusy, LM | 1 |
| Troshynski, TJ | 1 |
| Weisman, SJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phantom Motor Execution Via Myoelectric Pattern Recognition, Virtual and Augmented Reality, and Serious Gaming as a Treatment of Phantom Limb Pain[NCT03112928] | 77 participants (Actual) | Interventional | 2017-05-08 | Completed | |||
| Myoelectrically Controlled Augmented Reality and Gaming for the Treatment of Phantom Limb Pain[NCT02281539] | 14 participants (Actual) | Interventional | 2014-09-30 | Completed | |||
| The Effects of Targeted Phantom Motor Execution, Prosthetic Embodiment, and Surgical Closure on Phantom Limb Control, and Physical Function in People With Unilateral (Single) Transtibial (Below-the-knee) Amputation[NCT05247827] | 30 participants (Actual) | Interventional | 2022-06-01 | Completed | |||
| Mindful SensoriMotor Therapy With Brain Modulation for the Treatment of Pain in Individuals With Disarticulation or Nerve Injuries: A Single Arm Clinical Trial[NCT04897425] | 8 participants (Anticipated) | Interventional | 2022-06-01 | Not yet recruiting | |||
| Electromyography-controlled Virtual Reality and Serious Gaming to Improve Upper Extremity Function in Chronic Stroke Patients[NCT04154371] | 6 participants (Actual) | Interventional | 2019-11-11 | Active, not recruiting | |||
| Double Blind, Randomized, Placebo Controlled Clinical Trial to Evaluate the Efficacy of Repetitive Transcranial Magnetic Stimulation in Patients Victims of Landmines With Phantom Limb Pain[NCT01872481] | Phase 3 | 54 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for gamma-aminobutyric acid and Phantom Limb
| Article | Year |
|---|---|
[Burning sensation in oral cavity--burning mouth syndrome in everyday medical practice].
Topics: Acetamides; Amines; Anti-Anxiety Agents; Antidepressive Agents; Antioxidants; Burning Mouth Syndrome | 2012 |
Efficacy of gabapentin for treatment of adults with phantom limb pain.
Topics: Administration, Oral; Adult; Amines; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; | 2012 |
Pain management in the traumatic amputee.
Topics: Acute Disease; Afghanistan; Amines; Amputation, Traumatic; Analgesia; Analgesics; Benchmarking; Caus | 2008 |
2 trials available for gamma-aminobutyric acid and Phantom Limb
9 other studies available for gamma-aminobutyric acid and Phantom Limb
| Article | Year |
|---|---|
An observational descriptive study of the epidemiology and treatment of neuropathic pain in a UK general population.
Topics: Acetaminophen; Adolescent; Adult; Aged; Amines; Amitriptyline; Analgesics, Non-Narcotic; Analgesics, | 2013 |
Phantom organ pain syndrome, a ghostly visitor to the ED.
Topics: Adult; Amines; Analgesics; Cyclohexanecarboxylic Acids; Emergency Service, Hospital; Gabapentin; gam | 2014 |
One from column A and one from column B: may I take your order?
Topics: Amines; Analgesics, Opioid; Anti-Arrhythmia Agents; Cyclohexanecarboxylic Acids; Gabapentin; gamma-A | 2008 |
Calcitonin for phantom limb pain in a pregnant woman.
Topics: Adult; Amines; Amputation, Surgical; Analgesics, Opioid; Calcitonin; Carbamazepine; Cyclohexanecarbo | 2012 |
Flumazenil and dialysis for gabapentin-induced coma.
Topics: Acetates; Aged; Aged, 80 and over; Amines; Analgesics; Antidotes; Coma; Cyclohexanecarboxylic Acids; | 2003 |
Salt and wounds: a new mechanism for neuropathic pain.
Topics: Animals; Disease Models, Animal; gamma-Aminobutyric Acid; Glycine; Humans; K Cl- Cotransporters; Ner | 2003 |
The experience of phantom limb pain in patients with combat-related traumatic amputations.
Topics: Adolescent; Adult; Amines; Amputation, Traumatic; Amputees; Analgesics; Cyclohexanecarboxylic Acids; | 2008 |
Psychomotor agitation following gabapentin use in brain injury.
Topics: Acetates; Adult; Akathisia, Drug-Induced; Amines; Analgesics; Brain Injuries; Cyclohexanecarboxylic | 1997 |
Gabapentin in phantom limb pain management in children and young adults: report of seven cases.
Topics: Acetates; Adult; Amines; Analgesics; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Female; G | 2001 |