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gamma-aminobutyric acid and Pain, Breakthrough

gamma-aminobutyric acid has been researched along with Pain, Breakthrough in 2 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the analgesic effect of pregabalin combined with intrathecal sufentanil infusion for the treatment of breakthrough pain in patients with bone metastases."9.19[Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014)
"A total of 60 breakthrough pain patients with bone metastases were randomly divided to 3 groups: group A (pregabalin combined with intrathecal sufentanil infusion group, n=20), group B (placebo combined with intrathecal sufentanil infusion group, n=20) and group C (oral morphine sulfate controlled-release tablet group, n=20)."9.19[Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014)
"Pregabalin combined with intrathecal sufentanil infusion can effectively relieve breakthrough pain in patients with bone metastases."9.19[Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014)
"To evaluate the analgesic effect of pregabalin combined with intrathecal sufentanil infusion for the treatment of breakthrough pain in patients with bone metastases."6.79[Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014)
"A total of 60 breakthrough pain patients with bone metastases were randomly divided to 3 groups: group A (pregabalin combined with intrathecal sufentanil infusion group, n=20), group B (placebo combined with intrathecal sufentanil infusion group, n=20) and group C (oral morphine sulfate controlled-release tablet group, n=20)."6.79[Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014)
"Pregabalin combined with intrathecal sufentanil infusion can effectively relieve breakthrough pain in patients with bone metastases."6.79[Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014)
"To evaluate the analgesic effect of pregabalin combined with intrathecal sufentanil infusion for the treatment of breakthrough pain in patients with bone metastases."5.19[Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014)
"A total of 60 breakthrough pain patients with bone metastases were randomly divided to 3 groups: group A (pregabalin combined with intrathecal sufentanil infusion group, n=20), group B (placebo combined with intrathecal sufentanil infusion group, n=20) and group C (oral morphine sulfate controlled-release tablet group, n=20)."5.19[Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014)
"Pregabalin combined with intrathecal sufentanil infusion can effectively relieve breakthrough pain in patients with bone metastases."5.19[Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014)
"To evaluate the analgesic effect of pregabalin combined with intrathecal sufentanil infusion for the treatment of breakthrough pain in patients with bone metastases."2.79[Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014)
"A total of 60 breakthrough pain patients with bone metastases were randomly divided to 3 groups: group A (pregabalin combined with intrathecal sufentanil infusion group, n=20), group B (placebo combined with intrathecal sufentanil infusion group, n=20) and group C (oral morphine sulfate controlled-release tablet group, n=20)."2.79[Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014)
"Pregabalin combined with intrathecal sufentanil infusion can effectively relieve breakthrough pain in patients with bone metastases."2.79[Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases]. ( Cao, Q; Gu, S; Huang, D; Wu, L; Xu, H, 2014)
"Opioid-induced hyperalgesia has recently been described as representing a challenge for physicians in the clinical setting."2.50Managing difficult pain conditions in the cancer patient. ( Mercadante, S, 2014)
"Whereas most pain due to cancer can be relieved with relatively simple methods using oral analgesics, as suggested by WHO guidelines, some patients may have difficult pain situations that require more complex approaches."2.50Managing difficult pain conditions in the cancer patient. ( Mercadante, S, 2014)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mercadante, S1
Cao, Q1
Huang, D1
Xu, H1
Wu, L1
Gu, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pain Phenotyping of Patients With Bone Cancer Pain[NCT03908853]70 participants (Anticipated)Observational2019-02-05Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for gamma-aminobutyric acid and Pain, Breakthrough

ArticleYear
Managing difficult pain conditions in the cancer patient.
    Current pain and headache reports, 2014, Volume: 18, Issue:2

    Topics: Amines; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Breakthrough Pain; Cyclohexanec

2014

Trials

1 trial available for gamma-aminobutyric acid and Pain, Breakthrough

ArticleYear
[Pregabalin combined with intrathecal sufentanil infusion for breakthrough pain in patients with bone metastases].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2014, Volume: 39, Issue:4

    Topics: Analgesics, Opioid; Bone Neoplasms; Breakthrough Pain; gamma-Aminobutyric Acid; Humans; Injections,

2014