gamma-aminobutyric acid has been researched along with Osteoarthritis of Knee in 5 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We sought to compare a group (Group L) (n=21) of patients that underwent total knee arthroplasty and received a single preoperative dose of pregabalin combined with a COX-2 inhibitor with a control group (Group C) (n=20) that only received a COX-2 inhibitor in terms of (1) acute postoperative pain intensity, (2) analgesic consumption, and (3) functional recovery." | 2.80 | The effect of a single dose of preemptive pregabalin administered with COX-2 inhibitor: a trial in total knee arthroplasty. ( Choi, CH; Chung, KS; Lee, JK, 2015) |
| "Outcome measures were postsurgical pain at rest and during walking, consumption of opioids for pain rescue, knee swelling and knee range of motion, and complications." | 1.46 | Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty. ( Hansen, TB; Munk, S; Rytter, S; Stilling, M, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ohtori, S | 1 |
| Inoue, G | 1 |
| Orita, S | 1 |
| Takaso, M | 1 |
| Eguchi, Y | 1 |
| Ochiai, N | 1 |
| Kishida, S | 1 |
| Kuniyoshi, K | 1 |
| Aoki, Y | 1 |
| Ishikawa, T | 1 |
| Miyagi, M | 1 |
| Kamoda, H | 1 |
| Suzkuki, M | 1 |
| Nakamura, J | 1 |
| Kubota, G | 1 |
| Sakuma, Y | 1 |
| Oikawa, Y | 1 |
| Toyone, T | 1 |
| Inage, K | 1 |
| Sainoh, T | 1 |
| Yamauchi, K | 1 |
| Takahashi, K | 1 |
| Lee, JK | 1 |
| Chung, KS | 1 |
| Choi, CH | 1 |
| Rytter, S | 1 |
| Stilling, M | 1 |
| Munk, S | 1 |
| Hansen, TB | 1 |
| Reckziegel, D | 1 |
| Raschke, F | 1 |
| Cottam, WJ | 1 |
| Auer, DP | 1 |
| Bove, SE | 1 |
| Laemont, KD | 1 |
| Brooker, RM | 1 |
| Osborn, MN | 1 |
| Sanchez, BM | 1 |
| Guzman, RE | 1 |
| Hook, KE | 1 |
| Juneau, PL | 1 |
| Connor, JR | 1 |
| Kilgore, KS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Impact of Pre-emptive Large Doses of Methylprednisolone Combined With Gabapentin on Pain Treatment and Convalescence After Total Knee Arthroplasty in Elderly: A Double-blind Randomized Study[NCT04653415] | Phase 4 | 160 participants (Actual) | Interventional | 2019-06-01 | Completed | ||
| The Effect of Preoperative Steroids Injection on Pain and Oedema After Total Knee Arthroplasty . A Double -Blinded Randomized Controlled Study.[NCT04084912] | Phase 3 | 86 participants (Anticipated) | Interventional | 2020-01-01 | Not yet recruiting | ||
| Efficacy of Steroids on Functional Outcomes After Musculoskeletal Injuries of the Hand[NCT05003596] | Phase 2/Phase 3 | 60 participants (Anticipated) | Interventional | 2021-09-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for gamma-aminobutyric acid and Osteoarthritis of Knee
| Article | Year |
|---|---|
Efficacy of combination of meloxicam and pregabalin for pain in knee osteoarthritis.
Topics: Aged; Aged, 80 and over; Drug Therapy, Combination; Female; gamma-Aminobutyric Acid; Humans; Male; M | 2013 |
The effect of a single dose of preemptive pregabalin administered with COX-2 inhibitor: a trial in total knee arthroplasty.
Topics: Aged; Analgesics; Arthroplasty, Replacement, Knee; Cyclooxygenase 2 Inhibitors; gamma-Aminobutyric A | 2015 |
3 other studies available for gamma-aminobutyric acid and Osteoarthritis of Knee
| Article | Year |
|---|---|
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Cingulate GABA levels inversely correlate with the intensity of ongoing chronic knee osteoarthritis pain.
Topics: Aged; Demography; Female; gamma-Aminobutyric Acid; Gyrus Cinguli; Humans; Magnetic Resonance Imaging | 2016 |
Surgically induced osteoarthritis in the rat results in the development of both osteoarthritis-like joint pain and secondary hyperalgesia.
Topics: Amines; Analgesics; Animals; Arthralgia; Cyclohexanecarboxylic Acids; Cyclooxygenase 2 Inhibitors; D | 2006 |