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gamma-aminobutyric acid and Neoplasm Metastasis

gamma-aminobutyric acid has been researched along with Neoplasm Metastasis in 8 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
"5-Fluorouracil (5-FU) is an essential drug in systemic chemotherapy treatments for colorectal cancer (CRC)."4.02GABA-producing Lactobacillus plantarum inhibits metastatic properties and induces apoptosis of 5-FU-resistant colorectal cancer cells via GABA ( An, J; Ha, EM; Seok, H, 2021)
" We present a case of asterixis as a cause of falls and near falls in a patient with metastatic breast cancer and normal mental status who was receiving gabapentin."3.73Asterixis related to gabapentin as a cause of falls. ( Babiy, M; Hand, M; Herklotz, M; Stubblefield, MD, 2005)
" Of 11 transplantable and 7,12-dimethylbenz[a]anthracene-induced adenocarcinomas of the rat, all nonmetastasizing tumors could be distinguished from metastasizing tumors by the accumulation of high glutamine pools and significant-to-high cystathionine pools."3.66Free amino acid pools of rodent mammary tumors. ( Ip, C; Kim, U; Pine, MJ, 1982)
"5-Fluorouracil (5-FU) is an essential drug in systemic chemotherapy treatments for colorectal cancer (CRC)."1.62GABA-producing Lactobacillus plantarum inhibits metastatic properties and induces apoptosis of 5-FU-resistant colorectal cancer cells via GABA ( An, J; Ha, EM; Seok, H, 2021)
"Bidirectional interplay of breast cancer cells and native brain cells in metastasis is poorly understood and rarely studied."1.40Human breast cancer metastases to the brain display GABAergic properties in the neural niche. ( Choy, C; Hambrecht, AC; Jandial, R; Kowolik, CM; Li, H; Neman, J; Roberts, E; Termini, J; Vaidehi, N; Wilczynski, S, 2014)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
An, J1
Seok, H1
Ha, EM1
Okawa, T1
Hara, K1
Goto, M1
Kikuchi, M1
Kogane, M1
Hatakeyama, H1
Tanaka, H1
Shirane, D1
Akita, H1
Hisaka, A1
Sato, H1
Neman, J1
Termini, J1
Wilczynski, S1
Vaidehi, N1
Choy, C1
Kowolik, CM1
Li, H1
Hambrecht, AC1
Roberts, E1
Jandial, R1
Ortega, A1
Azuma, H1
Inamoto, T1
Sakamoto, T1
Kiyama, S1
Ubai, T1
Shinohara, Y1
Maemura, K1
Tsuji, M1
Segawa, N1
Masuda, H1
Takahara, K1
Katsuoka, Y1
Watanabe, M1
Babiy, M1
Stubblefield, MD1
Herklotz, M1
Hand, M1
Ippolito, JE1
Merritt, ME1
Bäckhed, F1
Moulder, KL1
Mennerick, S1
Manchester, JK1
Gammon, ST1
Piwnica-Worms, D1
Gordon, JI1
Pine, MJ1
Kim, U1
Ip, C1

Reviews

1 review available for gamma-aminobutyric acid and Neoplasm Metastasis

ArticleYear
A new role for GABA: inhibition of tumor cell migration.
    Trends in pharmacological sciences, 2003, Volume: 24, Issue:4

    Topics: Animals; Baclofen; Cell Movement; GABA Agonists; gamma-Aminobutyric Acid; Humans; Neoplasm Invasiven

2003

Other Studies

7 other studies available for gamma-aminobutyric acid and Neoplasm Metastasis

ArticleYear
GABA-producing Lactobacillus plantarum inhibits metastatic properties and induces apoptosis of 5-FU-resistant colorectal cancer cells via GABA
    Journal of microbiology (Seoul, Korea), 2021, Volume: 59, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Colorectal Neoplasms; Drug Resistance, Neoplasm; Fluorouracil; gam

2021
Effects on Metabolism in Astrocytes Caused by cGAMP, Which Imitates the Initial Stage of Brain Metastasis.
    International journal of molecular sciences, 2021, Aug-21, Volume: 22, Issue:16

    Topics: Animals; Astrocytes; Brain Neoplasms; gamma-Aminobutyric Acid; Glucose; Neoplasm Metastasis; Nucleot

2021
Human breast cancer metastases to the brain display GABAergic properties in the neural niche.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Jan-21, Volume: 111, Issue:3

    Topics: 4-Aminobutyrate Transaminase; Brain Neoplasms; Breast Neoplasms; Cell Adhesion Molecules, Neuronal;

2014
Gamma-aminobutyric acid as a promoting factor of cancer metastasis; induction of matrix metalloproteinase production is potentially its underlying mechanism.
    Cancer research, 2003, Dec-01, Volume: 63, Issue:23

    Topics: Aged; Aged, 80 and over; Baclofen; Dipeptides; Enzyme Induction; GABA Agonists; GABA-B Receptor Agon

2003
Asterixis related to gabapentin as a cause of falls.
    American journal of physical medicine & rehabilitation, 2005, Volume: 84, Issue:2

    Topics: Accidental Falls; Aged; Amines; Analgesics; Breast Neoplasms; Cyclohexanecarboxylic Acids; Diagnosis

2005
Linkage between cellular communications, energy utilization, and proliferation in metastatic neuroendocrine cancers.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Aug-15, Volume: 103, Issue:33

    Topics: Animals; Calcium; Cell Communication; Cell Proliferation; Citric Acid Cycle; Energy Metabolism; gamm

2006
Free amino acid pools of rodent mammary tumors.
    Journal of the National Cancer Institute, 1982, Volume: 69, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Amino Acids; Animals; Arginine; Cystathionine; Fem

1982